Description : (at2g31970 : 400.0) Encodes the Arabidopsis RAD50 homologue. It is involved in double strand break repair. Component of the meiotic recombination complex that processes meiotic double-strand-breaks to produce single-stranded DNA ends, which act in the homology search and recombination. Accumulates in the nucleus during meiotic prophase, a process regulated by PHS1.; RAD50; FUNCTIONS IN: zinc ion binding, ATP binding, nuclease activity; INVOLVED IN: DNA repair, double-strand break repair, telomere capping, mitotic recombination, telomere maintenance; LOCATED IN: nucleus, Mre11 complex, cytoplasm; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Zinc hook, Rad50 (InterPro:IPR013134), Rad50 zinc hook (InterPro:IPR007517), Recombination/repair protein Rad50 (InterPro:IPR004584); Has 105617 Blast hits to 56308 proteins in 2913 species: Archae - 1820; Bacteria - 19240; Metazoa - 45759; Fungi - 8381; Plants - 4805; Viruses - 470; Other Eukaryotes - 25142 (source: NCBI BLink). & (reliability: 800.0) & (original description: no original description)
Gene families : OG_42_0007556 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0007556_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Porphyridium release: evm.model.contig_4590.2 | |
Cluster | HCCA clusters: Cluster_77 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
405818 | No alias | DNA repair-recombination protein (RAD50) | 0.02 | Orthogroups_2024-Update |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No GO annotation available for this sequence |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0003864 | 3-methyl-2-oxobutanoate hydroxymethyltransferase activity | IEP | Predicted GO |
CC | GO:0005789 | endoplasmic reticulum membrane | IEP | Predicted GO |
BP | GO:0006508 | proteolysis | IEP | Predicted GO |
BP | GO:0006575 | cellular modified amino acid metabolic process | IEP | Predicted GO |
BP | GO:0006766 | vitamin metabolic process | IEP | Predicted GO |
BP | GO:0006767 | water-soluble vitamin metabolic process | IEP | Predicted GO |
MF | GO:0008233 | peptidase activity | IEP | Predicted GO |
MF | GO:0008234 | cysteine-type peptidase activity | IEP | Predicted GO |
BP | GO:0009110 | vitamin biosynthetic process | IEP | Predicted GO |
BP | GO:0015939 | pantothenate metabolic process | IEP | Predicted GO |
BP | GO:0015940 | pantothenate biosynthetic process | IEP | Predicted GO |
BP | GO:0016579 | protein deubiquitination | IEP | Predicted GO |
MF | GO:0016742 | hydroxymethyl-, formyl- and related transferase activity | IEP | Predicted GO |
MF | GO:0019783 | ubiquitin-like protein-specific protease activity | IEP | Predicted GO |
MF | GO:0036459 | thiol-dependent ubiquitinyl hydrolase activity | IEP | Predicted GO |
BP | GO:0042364 | water-soluble vitamin biosynthetic process | IEP | Predicted GO |
BP | GO:0042398 | cellular modified amino acid biosynthetic process | IEP | Predicted GO |
CC | GO:0044432 | endoplasmic reticulum part | IEP | Predicted GO |
MF | GO:0046873 | metal ion transmembrane transporter activity | IEP | Predicted GO |
MF | GO:0070011 | peptidase activity, acting on L-amino acid peptides | IEP | Predicted GO |
BP | GO:0070646 | protein modification by small protein removal | IEP | Predicted GO |
BP | GO:0070647 | protein modification by small protein conjugation or removal | IEP | Predicted GO |
MF | GO:0101005 | ubiquitinyl hydrolase activity | IEP | Predicted GO |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR038729 | Rad50/SbcC_AAA | 9 | 222 |
No external refs found! |