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  5. evm.model.contig_468.4

evm.model.contig_468.4


Description : (at5g40820 : 342.0) Encodes a Arabidopsis ortholog of the ATR protein kinase that is involved in a wide range of responses to DNA damage and plays a central role in cell-cycle regulation. Dominant loss of function alleles identified as suppressors of ALS also exhibit increased tolerance to aluminum. This may be due to the inhibition of terminal differentiation of the root apex upon exposure to Al.; Ataxia telangiectasia-mutated and RAD3-related (ATR); FUNCTIONS IN: protein serine/threonine kinase activity, inositol or phosphatidylinositol kinase activity, binding, phosphotransferase activity, alcohol group as acceptor; INVOLVED IN: in 9 processes; EXPRESSED IN: 10 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: Phosphatidylinositol 3-/4-kinase, catalytic (InterPro:IPR000403), UME (InterPro:IPR012993), Protein kinase-like domain (InterPro:IPR011009), PIK-related kinase, FAT (InterPro:IPR003151), Armadillo-type fold (InterPro:IPR016024), PIK-related kinase (InterPro:IPR014009), Phosphatidylinositol 3/4-kinase, conserved site (InterPro:IPR018936), PIK-related kinase, FATC (InterPro:IPR003152); BEST Arabidopsis thaliana protein match is: ataxia-telangiectasia mutated (TAIR:AT3G48190.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (q5z987|atr_orysa : 288.0) Serine/threonine-protein kinase ATR (EC 2.7.11.1) - Oryza sativa (Rice) & (reliability: 684.0) & (original description: no original description)


Gene families : OG_42_0007184 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0007184_tree

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Porphyridium release: evm.model.contig_468.4
Cluster HCCA clusters: Cluster_6

Target Alias Description ECC score Gene Family Method Actions
Glyma.10G284200 No alias Ataxia telangiectasia-mutated and RAD3-related 0.02 Orthogroups_2024-Update
HORVU7Hr1G118750.3 No alias kinase component *(ATR) of ATR-ATRIP DNA damage sensor complex 0.02 Orthogroups_2024-Update
evm.model.tig00020537.65 No alias (q5z987|atr_orysa : 139.0) Serine/threonine-protein... 0.02 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0004674 protein serine/threonine kinase activity IEA InterProScan predictions
MF GO:0005515 protein binding IEA InterProScan predictions
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Type GO Term Name Evidence Source
BP GO:0000096 sulfur amino acid metabolic process IEP Predicted GO
BP GO:0000097 sulfur amino acid biosynthetic process IEP Predicted GO
BP GO:0000375 RNA splicing, via transesterification reactions IEP Predicted GO
BP GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile IEP Predicted GO
BP GO:0000398 mRNA splicing, via spliceosome IEP Predicted GO
BP GO:0000726 non-recombinational repair IEP Predicted GO
MF GO:0003678 DNA helicase activity IEP Predicted GO
MF GO:0003756 protein disulfide isomerase activity IEP Predicted GO
MF GO:0004003 ATP-dependent DNA helicase activity IEP Predicted GO
MF GO:0004525 ribonuclease III activity IEP Predicted GO
CC GO:0005783 endoplasmic reticulum IEP Predicted GO
BP GO:0006302 double-strand break repair IEP Predicted GO
BP GO:0006303 double-strand break repair via nonhomologous end joining IEP Predicted GO
BP GO:0006396 RNA processing IEP Predicted GO
BP GO:0006555 methionine metabolic process IEP Predicted GO
MF GO:0008026 ATP-dependent helicase activity IEP Predicted GO
MF GO:0008168 methyltransferase activity IEP Predicted GO
MF GO:0008172 S-methyltransferase activity IEP Predicted GO
MF GO:0008705 methionine synthase activity IEP Predicted GO
BP GO:0009067 aspartate family amino acid biosynthetic process IEP Predicted GO
BP GO:0009086 methionine biosynthetic process IEP Predicted GO
MF GO:0016763 transferase activity, transferring pentosyl groups IEP Predicted GO
MF GO:0016860 intramolecular oxidoreductase activity IEP Predicted GO
MF GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds IEP Predicted GO
MF GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters IEP Predicted GO
MF GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters IEP Predicted GO
MF GO:0017069 snRNA binding IEP Predicted GO
MF GO:0017070 U6 snRNA binding IEP Predicted GO
MF GO:0030623 U5 snRNA binding IEP Predicted GO
MF GO:0031419 cobalamin binding IEP Predicted GO
MF GO:0032296 double-stranded RNA-specific ribonuclease activity IEP Predicted GO
MF GO:0042084 5-methyltetrahydrofolate-dependent methyltransferase activity IEP Predicted GO
BP GO:0042558 pteridine-containing compound metabolic process IEP Predicted GO
BP GO:0044272 sulfur compound biosynthetic process IEP Predicted GO
MF GO:0070035 purine NTP-dependent helicase activity IEP Predicted GO
InterPro domains Description Start Stop
IPR000403 PI3/4_kinase_cat_dom 3083 3317
IPR012993 UME 1267 1397
IPR003152 FATC_dom 3364 3395
No external refs found!