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  5. evm.model.contig_503.8

evm.model.contig_503.8


Description : (at3g01120 : 407.0) encodes a cystathionine gamma-synthase, which performs the first committed step in methionine biosynthesis. A conserved motif of 13 amino acids in the first exon is required for posttranscriptional autoregulation. This enzyme shares the same substrate as threonine synthase (TS) and its absence transcriptionally affects 8 genes in the genome.; METHIONINE OVERACCUMULATION 1 (MTO1); FUNCTIONS IN: cystathionine gamma-synthase activity; INVOLVED IN: methionine biosynthetic process; LOCATED IN: chloroplast; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Pyridoxal phosphate-dependent transferase, major domain (InterPro:IPR015424), Cys/Met metabolism, pyridoxal phosphate-dependent enzyme (InterPro:IPR000277), Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (InterPro:IPR015421), Pyridoxal phosphate-dependent transferase, major region, subdomain 2 (InterPro:IPR015422); BEST Arabidopsis thaliana protein match is: Pyridoxal phosphate (PLP)-dependent transferases superfamily protein (TAIR:AT1G33320.1); Has 21364 Blast hits to 20702 proteins in 2452 species: Archae - 220; Bacteria - 11705; Metazoa - 241; Fungi - 842; Plants - 284; Viruses - 13; Other Eukaryotes - 8059 (source: NCBI BLink). & (reliability: 814.0) & (original description: no original description)


Gene families : OG_42_0001443 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0001443_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Porphyridium release: evm.model.contig_503.8
Cluster HCCA clusters: Cluster_45

Target Alias Description ECC score Gene Family Method Actions
Mp1g04580.1 No alias cystathionine beta-lyase 0.02 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0030170 pyridoxal phosphate binding IEA InterProScan predictions
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Type GO Term Name Evidence Source
MF GO:0000166 nucleotide binding IEP Predicted GO
MF GO:0001882 nucleoside binding IEP Predicted GO
MF GO:0001883 purine nucleoside binding IEP Predicted GO
MF GO:0003676 nucleic acid binding IEP Predicted GO
MF GO:0003723 RNA binding IEP Predicted GO
MF GO:0003743 translation initiation factor activity IEP Predicted GO
MF GO:0003747 translation release factor activity IEP Predicted GO
MF GO:0004455 ketol-acid reductoisomerase activity IEP Predicted GO
MF GO:0004812 aminoacyl-tRNA ligase activity IEP Predicted GO
MF GO:0004817 cysteine-tRNA ligase activity IEP Predicted GO
MF GO:0005524 ATP binding IEP Predicted GO
MF GO:0005525 GTP binding IEP Predicted GO
CC GO:0005730 nucleolus IEP Predicted GO
BP GO:0006399 tRNA metabolic process IEP Predicted GO
BP GO:0006413 translational initiation IEP Predicted GO
BP GO:0006415 translational termination IEP Predicted GO
BP GO:0006418 tRNA aminoacylation for protein translation IEP Predicted GO
BP GO:0006423 cysteinyl-tRNA aminoacylation IEP Predicted GO
BP GO:0006457 protein folding IEP Predicted GO
BP GO:0006520 cellular amino acid metabolic process IEP Predicted GO
MF GO:0008079 translation termination factor activity IEP Predicted GO
MF GO:0008134 transcription factor binding IEP Predicted GO
MF GO:0008135 translation factor activity, RNA binding IEP Predicted GO
MF GO:0008408 3'-5' exonuclease activity IEP Predicted GO
BP GO:0009081 branched-chain amino acid metabolic process IEP Predicted GO
BP GO:0009082 branched-chain amino acid biosynthetic process IEP Predicted GO
MF GO:0015095 magnesium ion transmembrane transporter activity IEP Predicted GO
BP GO:0015693 magnesium ion transport IEP Predicted GO
MF GO:0016614 oxidoreductase activity, acting on CH-OH group of donors IEP Predicted GO
MF GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEP Predicted GO
MF GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors IEP Predicted GO
MF GO:0016763 transferase activity, transferring pentosyl groups IEP Predicted GO
MF GO:0016875 ligase activity, forming carbon-oxygen bonds IEP Predicted GO
MF GO:0017076 purine nucleotide binding IEP Predicted GO
MF GO:0019001 guanyl nucleotide binding IEP Predicted GO
BP GO:0022411 cellular component disassembly IEP Predicted GO
BP GO:0022613 ribonucleoprotein complex biogenesis IEP Predicted GO
MF GO:0030554 adenyl nucleotide binding IEP Predicted GO
MF GO:0031406 carboxylic acid binding IEP Predicted GO
MF GO:0031418 L-ascorbic acid binding IEP Predicted GO
MF GO:0032549 ribonucleoside binding IEP Predicted GO
MF GO:0032550 purine ribonucleoside binding IEP Predicted GO
MF GO:0032553 ribonucleotide binding IEP Predicted GO
MF GO:0032555 purine ribonucleotide binding IEP Predicted GO
MF GO:0032559 adenyl ribonucleotide binding IEP Predicted GO
MF GO:0032561 guanyl ribonucleotide binding IEP Predicted GO
BP GO:0032984 protein-containing complex disassembly IEP Predicted GO
BP GO:0034660 ncRNA metabolic process IEP Predicted GO
MF GO:0035639 purine ribonucleoside triphosphate binding IEP Predicted GO
BP GO:0042254 ribosome biogenesis IEP Predicted GO
BP GO:0043038 amino acid activation IEP Predicted GO
BP GO:0043039 tRNA aminoacylation IEP Predicted GO
MF GO:0043177 organic acid binding IEP Predicted GO
BP GO:0043624 cellular protein complex disassembly IEP Predicted GO
BP GO:0044085 cellular component biogenesis IEP Predicted GO
MF GO:0048029 monosaccharide binding IEP Predicted GO
BP GO:0055114 oxidation-reduction process IEP Predicted GO
BP GO:0070838 divalent metal ion transport IEP Predicted GO
BP GO:0071840 cellular component organization or biogenesis IEP Predicted GO
BP GO:0072511 divalent inorganic cation transport IEP Predicted GO
MF GO:0097367 carbohydrate derivative binding IEP Predicted GO
MF GO:1901265 nucleoside phosphate binding IEP Predicted GO
InterPro domains Description Start Stop
IPR000277 Cys/Met-Metab_PyrdxlP-dep_enz 170 558
No external refs found!