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Description : (at4g03240 : 84.3) Encodes AtFH, a frataxin homolog. Frataxin is required for the biogenesis of mitochondria in different organisms. AtFH knock-out mutants are lethal. Required for full activity of mitochondrial Fe-S proteins. Deficiency of AtFH induces oxidative stress.; frataxin homolog (FH); CONTAINS InterPro DOMAIN/s: Frataxin (InterPro:IPR017789), Frataxin conserved site (InterPro:IPR020895), Frataxin-like (InterPro:IPR002908); Has 1148 Blast hits to 1148 proteins in 551 species: Archae - 0; Bacteria - 783; Metazoa - 128; Fungi - 127; Plants - 48; Viruses - 0; Other Eukaryotes - 62 (source: NCBI BLink). & (reliability: 168.6) & (original description: no original description)
Gene families : OG_42_0007592 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0007592_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
| Type | Description | Actions |
|---|---|---|
| Neighborhood | Porphyridium release: evm.model.contig_560.1 | |
| Cluster | HCCA clusters: Cluster_56 |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
| MF | GO:0008199 | ferric iron binding | IEA | InterProScan predictions |
| BP | GO:0016226 | iron-sulfur cluster assembly | IEA | InterProScan predictions |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
| MF | GO:0003909 | DNA ligase activity | IEP | Predicted GO |
| MF | GO:0003910 | DNA ligase (ATP) activity | IEP | Predicted GO |
| MF | GO:0003968 | RNA-directed 5'-3' RNA polymerase activity | IEP | Predicted GO |
| MF | GO:0004180 | carboxypeptidase activity | IEP | Predicted GO |
| MF | GO:0004181 | metallocarboxypeptidase activity | IEP | Predicted GO |
| MF | GO:0004427 | inorganic diphosphatase activity | IEP | Predicted GO |
| MF | GO:0004806 | triglyceride lipase activity | IEP | Predicted GO |
| BP | GO:0006629 | lipid metabolic process | IEP | Predicted GO |
| BP | GO:0006810 | transport | IEP | Predicted GO |
| BP | GO:0006811 | ion transport | IEP | Predicted GO |
| BP | GO:0006891 | intra-Golgi vesicle-mediated transport | IEP | Predicted GO |
| MF | GO:0008235 | metalloexopeptidase activity | IEP | Predicted GO |
| BP | GO:0010207 | photosystem II assembly | IEP | Predicted GO |
| MF | GO:0015075 | ion transmembrane transporter activity | IEP | Predicted GO |
| CC | GO:0016021 | integral component of membrane | IEP | Predicted GO |
| MF | GO:0016298 | lipase activity | IEP | Predicted GO |
| MF | GO:0016757 | transferase activity, transferring glycosyl groups | IEP | Predicted GO |
| MF | GO:0016886 | ligase activity, forming phosphoric ester bonds | IEP | Predicted GO |
| CC | GO:0030173 | integral component of Golgi membrane | IEP | Predicted GO |
| CC | GO:0031224 | intrinsic component of membrane | IEP | Predicted GO |
| CC | GO:0031228 | intrinsic component of Golgi membrane | IEP | Predicted GO |
| CC | GO:0031300 | intrinsic component of organelle membrane | IEP | Predicted GO |
| CC | GO:0031301 | integral component of organelle membrane | IEP | Predicted GO |
| CC | GO:0044425 | membrane part | IEP | Predicted GO |
| BP | GO:0051179 | localization | IEP | Predicted GO |
| BP | GO:0051234 | establishment of localization | IEP | Predicted GO |
| BP | GO:0055085 | transmembrane transport | IEP | Predicted GO |
| MF | GO:0071949 | FAD binding | IEP | Predicted GO |
| InterPro domains | Description | Start | Stop |
|---|---|---|---|
| IPR002908 | Frataxin/CyaY | 45 | 149 |
| No external refs found! |