Description : (at2g47000 : 919.0) Multidrug resistance P-glycoprotein (MDR/PGP) subfamily of ABC transporters. Functions in the basipetal redirection of auxin from the root tip. Exhibits apolar plasma membrane localization in the root cap and polar localization in tissues above.; ATP binding cassette subfamily B4 (ABCB4); FUNCTIONS IN: xenobiotic-transporting ATPase activity, ATPase activity, coupled to transmembrane movement of substances; INVOLVED IN: in 8 processes; LOCATED IN: plasma membrane, membrane; EXPRESSED IN: 14 plant structures; EXPRESSED DURING: 4 anthesis, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ABC transporter-like (InterPro:IPR003439), ABC transporter, transmembrane domain, type 1 (InterPro:IPR011527), ABC transporter integral membrane type 1 (InterPro:IPR017940), ABC transporter, transmembrane domain (InterPro:IPR001140), ABC transporter, conserved site (InterPro:IPR017871); BEST Arabidopsis thaliana protein match is: P-glycoprotein 21 (TAIR:AT3G62150.1); Has 844144 Blast hits to 390751 proteins in 4168 species: Archae - 14748; Bacteria - 659498; Metazoa - 17847; Fungi - 13026; Plants - 10001; Viruses - 45; Other Eukaryotes - 128979 (source: NCBI BLink). & (q6yuu5|mdr_orysa : 773.0) Putative multidrug resistance protein (P-glycoprotein) - Oryza sativa (Rice) & (reliability: 1838.0) & (original description: no original description)
Gene families : OG_42_0000040 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000040_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Porphyridium release: evm.model.contig_618.5 | |
Cluster | HCCA clusters: Cluster_76 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
176522 | No alias | ATP binding cassette subfamily B4 | 0.02 | Orthogroups_2024-Update | |
At3g28360 | No alias | ABC transporter B family member 16... | 0.02 | Orthogroups_2024-Update | |
At4g01820 | No alias | ABC transporter B family member 3... | 0.03 | Orthogroups_2024-Update | |
Brara.I01939.1 | No alias | subfamily ABCB transporter | 0.02 | Orthogroups_2024-Update | |
Glyma.03G224100 | No alias | P-glycoprotein 11 | 0.02 | Orthogroups_2024-Update | |
Glyma.14G220200 | No alias | P-glycoprotein 13 | 0.02 | Orthogroups_2024-Update | |
Glyma.17G259100 | No alias | P-glycoprotein 13 | 0.02 | Orthogroups_2024-Update | |
Kfl00461_0020 | kfl00461_0020_v1.1 | (at3g28860 : 1090.0) Belongs to the family of... | 0.02 | Orthogroups_2024-Update | |
Mp2g11920.1 | No alias | subfamily ABCB transporter | 0.02 | Orthogroups_2024-Update | |
Seita.1G145300.1 | No alias | subfamily ABCB transporter | 0.01 | Orthogroups_2024-Update | |
Seita.1G191000.1 | No alias | subfamily ABCB transporter | 0.02 | Orthogroups_2024-Update | |
Seita.7G029100.1 | No alias | ABC-B-type transporter *(AMN3) & subfamily ABCB transporter | 0.01 | Orthogroups_2024-Update | |
Solyc06g072960 | No alias | No description available | 0.01 | Orthogroups_2024-Update |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0005524 | ATP binding | IEA | InterProScan predictions |
CC | GO:0016021 | integral component of membrane | IEA | InterProScan predictions |
MF | GO:0016887 | ATPase activity | IEA | InterProScan predictions |
MF | GO:0042626 | ATPase activity, coupled to transmembrane movement of substances | IEA | InterProScan predictions |
BP | GO:0055085 | transmembrane transport | IEA | InterProScan predictions |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0003700 | DNA-binding transcription factor activity | IEP | Predicted GO |
BP | GO:0006511 | ubiquitin-dependent protein catabolic process | IEP | Predicted GO |
BP | GO:0009057 | macromolecule catabolic process | IEP | Predicted GO |
MF | GO:0016624 | oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor | IEP | Predicted GO |
CC | GO:0019773 | proteasome core complex, alpha-subunit complex | IEP | Predicted GO |
BP | GO:0019941 | modification-dependent protein catabolic process | IEP | Predicted GO |
BP | GO:0031123 | RNA 3'-end processing | IEP | Predicted GO |
BP | GO:0031124 | mRNA 3'-end processing | IEP | Predicted GO |
MF | GO:0043565 | sequence-specific DNA binding | IEP | Predicted GO |
BP | GO:0043632 | modification-dependent macromolecule catabolic process | IEP | Predicted GO |
BP | GO:0044248 | cellular catabolic process | IEP | Predicted GO |
BP | GO:0044265 | cellular macromolecule catabolic process | IEP | Predicted GO |
BP | GO:0051603 | proteolysis involved in cellular protein catabolic process | IEP | Predicted GO |
MF | GO:0140110 | transcription regulator activity | IEP | Predicted GO |
No external refs found! |