Description : (at1g15750 : 1653.0) Encodes a protein with several WD40 repeats at the C-terminus and predicted protein-protein interaction domains at the N-terminus. Together with the TOPLESS-RELATED PROTEINS (TPRs), it is thought to be involved in transcriptional repression of root-promoting genes in the top help of the embryo during the transition stage of embryogenesis. The ability of IAA12 to repress transcription is diminished in a tpl-1 mutant background.; TOPLESS (TPL); FUNCTIONS IN: protein binding, transcription repressor activity, protein homodimerization activity; INVOLVED IN: xylem and phloem pattern formation, response to auxin stimulus, primary shoot apical meristem specification, jasmonic acid mediated signaling pathway; LOCATED IN: cytosol, nucleus; EXPRESSED IN: 27 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: WD40 repeat 2 (InterPro:IPR019782), WD40 repeat, conserved site (InterPro:IPR019775), WD40 repeat (InterPro:IPR001680), CTLH, C-terminal LisH motif (InterPro:IPR006595), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), LisH dimerisation motif (InterPro:IPR006594), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: TOPLESS-related 1 (TAIR:AT1G80490.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). & (reliability: 3306.0) & (original description: no original description)
Gene families : OG_42_0000373 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000373_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Pseudotsuga release: PSME_00001044-RA | |
Cluster | HCCA clusters: Cluster_17 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
A4A49_21987 | No alias | protein tpr2 | 0.03 | Orthogroups_2024-Update | |
Bradi1g67800 | No alias | TOPLESS-related 1 | 0.04 | Orthogroups_2024-Update | |
Glyma.07G028000 | No alias | Transducin family protein / WD-40 repeat family protein | 0.03 | Orthogroups_2024-Update | |
Glyma.08G214600 | No alias | Transducin family protein / WD-40 repeat family protein | 0.04 | Orthogroups_2024-Update | |
MA_10430083g0010 | No alias | (at1g15750 : 1644.0) Encodes a protein with several WD40... | 0.06 | Orthogroups_2024-Update | |
MA_16979g0020 | No alias | (at1g15750 : 344.0) Encodes a protein with several WD40... | 0.03 | Orthogroups_2024-Update |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0005515 | protein binding | IEA | InterProScan predictions |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
BP | GO:0000290 | deadenylation-dependent decapping of nuclear-transcribed mRNA | IEP | Predicted GO |
CC | GO:0000428 | DNA-directed RNA polymerase complex | IEP | Predicted GO |
BP | GO:0000956 | nuclear-transcribed mRNA catabolic process | IEP | Predicted GO |
MF | GO:0003676 | nucleic acid binding | IEP | Predicted GO |
MF | GO:0003723 | RNA binding | IEP | Predicted GO |
MF | GO:0004652 | polynucleotide adenylyltransferase activity | IEP | Predicted GO |
CC | GO:0005665 | RNA polymerase II, core complex | IEP | Predicted GO |
BP | GO:0006139 | nucleobase-containing compound metabolic process | IEP | Predicted GO |
BP | GO:0006366 | transcription by RNA polymerase II | IEP | Predicted GO |
BP | GO:0006396 | RNA processing | IEP | Predicted GO |
BP | GO:0006401 | RNA catabolic process | IEP | Predicted GO |
BP | GO:0006402 | mRNA catabolic process | IEP | Predicted GO |
BP | GO:0006725 | cellular aromatic compound metabolic process | IEP | Predicted GO |
BP | GO:0006886 | intracellular protein transport | IEP | Predicted GO |
BP | GO:0006888 | ER to Golgi vesicle-mediated transport | IEP | Predicted GO |
MF | GO:0008047 | enzyme activator activity | IEP | Predicted GO |
BP | GO:0008104 | protein localization | IEP | Predicted GO |
BP | GO:0010629 | negative regulation of gene expression | IEP | Predicted GO |
BP | GO:0015031 | protein transport | IEP | Predicted GO |
BP | GO:0015833 | peptide transport | IEP | Predicted GO |
BP | GO:0016070 | RNA metabolic process | IEP | Predicted GO |
BP | GO:0016192 | vesicle-mediated transport | IEP | Predicted GO |
MF | GO:0016779 | nucleotidyltransferase activity | IEP | Predicted GO |
CC | GO:0030117 | membrane coat | IEP | Predicted GO |
CC | GO:0030119 | AP-type membrane coat adaptor complex | IEP | Predicted GO |
CC | GO:0030120 | vesicle coat | IEP | Predicted GO |
CC | GO:0030127 | COPII vesicle coat | IEP | Predicted GO |
CC | GO:0030131 | clathrin adaptor complex | IEP | Predicted GO |
CC | GO:0030880 | RNA polymerase complex | IEP | Predicted GO |
CC | GO:0032991 | protein-containing complex | IEP | Predicted GO |
BP | GO:0033036 | macromolecule localization | IEP | Predicted GO |
BP | GO:0042886 | amide transport | IEP | Predicted GO |
BP | GO:0043085 | positive regulation of catalytic activity | IEP | Predicted GO |
BP | GO:0043631 | RNA polyadenylation | IEP | Predicted GO |
BP | GO:0044093 | positive regulation of molecular function | IEP | Predicted GO |
CC | GO:0044424 | intracellular part | IEP | Predicted GO |
CC | GO:0044425 | membrane part | IEP | Predicted GO |
CC | GO:0044433 | cytoplasmic vesicle part | IEP | Predicted GO |
CC | GO:0044444 | cytoplasmic part | IEP | Predicted GO |
CC | GO:0044464 | cell part | IEP | Predicted GO |
BP | GO:0045184 | establishment of protein localization | IEP | Predicted GO |
BP | GO:0046483 | heterocycle metabolic process | IEP | Predicted GO |
BP | GO:0046907 | intracellular transport | IEP | Predicted GO |
BP | GO:0048193 | Golgi vesicle transport | IEP | Predicted GO |
BP | GO:0051641 | cellular localization | IEP | Predicted GO |
BP | GO:0051649 | establishment of localization in cell | IEP | Predicted GO |
CC | GO:0055029 | nuclear DNA-directed RNA polymerase complex | IEP | Predicted GO |
CC | GO:0061695 | transferase complex, transferring phosphorus-containing groups | IEP | Predicted GO |
MF | GO:0070566 | adenylyltransferase activity | IEP | Predicted GO |
BP | GO:0071702 | organic substance transport | IEP | Predicted GO |
BP | GO:0071705 | nitrogen compound transport | IEP | Predicted GO |
BP | GO:0090304 | nucleic acid metabolic process | IEP | Predicted GO |
CC | GO:0098796 | membrane protein complex | IEP | Predicted GO |
BP | GO:1901360 | organic cyclic compound metabolic process | IEP | Predicted GO |
CC | GO:1902494 | catalytic complex | IEP | Predicted GO |
CC | GO:1990234 | transferase complex | IEP | Predicted GO |
No external refs found! |