PSME_00005016-RA


Description : (at3g06483 : 489.0) Pyruvate dehydrogenase kinase (PDK) specifically phosphorylates the E1α subunit of the pyruvate dehydrogenase complex (PDC) on a Ser residue using ATP as a phosphate donor. PDK is a unique type of protein kinase having a His-kinase-like sequence but Ser-kinase activity. Site-directed mutagenesis and structural analysis indicate that PDK belongs to the GHKL superfamily.; pyruvate dehydrogenase kinase (PDK); FUNCTIONS IN: ATP binding, pyruvate dehydrogenase (acetyl-transferring) kinase activity, histidine phosphotransfer kinase activity; INVOLVED IN: signal transduction, peptidyl-histidine phosphorylation, phosphorylation; LOCATED IN: mitochondrion; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Signal transduction histidine kinase, core (InterPro:IPR005467), Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, mitochondrial (InterPro:IPR018955), ATPase-like, ATP-binding domain (InterPro:IPR003594), Signal transduction histidine kinase-related protein, C-terminal (InterPro:IPR004358); Has 1925 Blast hits to 1799 proteins in 531 species: Archae - 0; Bacteria - 712; Metazoa - 467; Fungi - 468; Plants - 102; Viruses - 0; Other Eukaryotes - 176 (source: NCBI BLink). & (reliability: 978.0) & (original description: no original description)


Gene families : OG_42_0003838 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0003838_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00005016-RA
Cluster HCCA clusters: Cluster_148

Target Alias Description ECC score Gene Family Method Actions
Brara.E03278.1 No alias pyruvate dehydrogenase kinase & EC_2.7 transferase... 0.03 Orthogroups_2024-Update
Cre06.g278451 No alias pyruvate dehydrogenase kinase 0.01 Orthogroups_2024-Update
LOC_Os07g44330 No alias kinase, putative, expressed 0.02 Orthogroups_2024-Update
Seita.2G405900.1 No alias pyruvate dehydrogenase kinase & EC_2.7 transferase... 0.05 Orthogroups_2024-Update
Sobic.002G390500.1 No alias pyruvate dehydrogenase kinase & EC_2.7 transferase... 0.05 Orthogroups_2024-Update

Type GO Term Name Evidence Source

No GO annotation available for this sequence

Type GO Term Name Evidence Source
MF GO:0003830 beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity IEP Predicted GO
MF GO:0004089 carbonate dehydratase activity IEP Predicted GO
MF GO:0005319 lipid transporter activity IEP Predicted GO
MF GO:0005506 iron ion binding IEP Predicted GO
BP GO:0006487 protein N-linked glycosylation IEP Predicted GO
BP GO:0006869 lipid transport IEP Predicted GO
MF GO:0008289 lipid binding IEP Predicted GO
MF GO:0008375 acetylglucosaminyltransferase activity IEP Predicted GO
BP GO:0016052 carbohydrate catabolic process IEP Predicted GO
BP GO:0019725 cellular homeostasis IEP Predicted GO
BP GO:0042592 homeostatic process IEP Predicted GO
BP GO:0045454 cell redox homeostasis IEP Predicted GO
BP GO:0050789 regulation of biological process IEP Predicted GO
BP GO:0050794 regulation of cellular process IEP Predicted GO
BP GO:0061024 membrane organization IEP Predicted GO
MF GO:0061630 ubiquitin protein ligase activity IEP Predicted GO
MF GO:0061659 ubiquitin-like protein ligase activity IEP Predicted GO
BP GO:0065007 biological regulation IEP Predicted GO
BP GO:0120009 intermembrane lipid transfer IEP Predicted GO
MF GO:0120013 intermembrane lipid transfer activity IEP Predicted GO
MF GO:0140103 catalytic activity, acting on a glycoprotein IEP Predicted GO
InterPro domains Description Start Stop
IPR018955 BCDHK/PDK_N 28 189
IPR003594 HATPase_C 233 357
No external refs found!