PSME_00006889-RA

Description : (at3g05530 : 267.0) Encodes RPT5a (Regulatory Particle 5a), one of the six AAA-ATPases of the proteasome regulatory particle. Essential for gametophyte development. In Arabidopsis, the RPT5 subunit is encoded by two highly homologous genes, RPT5a and RPT5b. RPT5a and RPT5b show accession-dependent functional redundancy. In Wassilewskija (Ws) accession: mutant alleles of RPT5a displayed 50% pollen lethality, indicating that RPT5a is essential for male gametophyte development. In the Columbia (Col) accession, a rpt5a mutant allele did not display such a phenotype because the RPT5b Col allele complements the rpt5a defect in the male gametophyte, whereas the RPT5b Ws allele does not. Double rpt5a rpt5b mutants in Col background showed a complete male and female gametophyte lethal phenotype.; regulatory particle triple-A ATPase 5A (RPT5A); CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ATPase, AAA-type, core (InterPro:IPR003959), ATPase, AAA-type, conserved site (InterPro:IPR003960), 26S proteasome subunit P45 (InterPro:IPR005937); BEST Arabidopsis thaliana protein match is: 26S proteasome AAA-ATPase subunit RPT5B (TAIR:AT1G09100.1); Has 33265 Blast hits to 30927 proteins in 3145 species: Archae - 1437; Bacteria - 12044; Metazoa - 4947; Fungi - 3672; Plants - 3322; Viruses - 56; Other Eukaryotes - 7787 (source: NCBI BLink). & (o23894|prs6a_bracm : 267.0) 26S protease regulatory subunit 6A homolog (TAT-binding protein homolog 1) (TBP-1) - Brassica campestris (Field mustard) & (reliability: 534.0) & (original description: no original description)

Gene families : OG_42_0003399 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0003399_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pseudotsuga release: PSME_00006889-RA
Cluster	HCCA clusters: Cluster_121

Target	Alias	Description	ECC score	Gene Family Method	Actions
Mp3g09490.1	No alias	regulatory component RPT5 of 26S proteasome	0.02	Orthogroups_2024-Update
evm.model.tig00001187.20	No alias	(p46465\|prs6a_orysa : 599.0) 26S protease regulatory...	0.03	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	InterProScan predictions
MF	GO:0008144	drug binding	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0001882	nucleoside binding	IEP	Predicted GO
MF	GO:0001883	purine nucleoside binding	IEP	Predicted GO
MF	GO:0003735	structural constituent of ribosome	IEP	Predicted GO
MF	GO:0003746	translation elongation factor activity	IEP	Predicted GO
MF	GO:0003924	GTPase activity	IEP	Predicted GO
MF	GO:0004298	threonine-type endopeptidase activity	IEP	Predicted GO
MF	GO:0004843	thiol-dependent ubiquitin-specific protease activity	IEP	Predicted GO
MF	GO:0005198	structural molecule activity	IEP	Predicted GO
MF	GO:0005525	GTP binding	IEP	Predicted GO
CC	GO:0005622	intracellular	IEP	Predicted GO
CC	GO:0005839	proteasome core complex	IEP	Predicted GO
CC	GO:0005852	eukaryotic translation initiation factor 3 complex	IEP	Predicted GO
BP	GO:0006412	translation	IEP	Predicted GO
BP	GO:0006414	translational elongation	IEP	Predicted GO
BP	GO:0006518	peptide metabolic process	IEP	Predicted GO
MF	GO:0008135	translation factor activity, RNA binding	IEP	Predicted GO
MF	GO:0009055	electron transfer activity	IEP	Predicted GO
BP	GO:0009059	macromolecule biosynthetic process	IEP	Predicted GO
MF	GO:0015035	protein disulfide oxidoreductase activity	IEP	Predicted GO
MF	GO:0015036	disulfide oxidoreductase activity	IEP	Predicted GO
CC	GO:0015934	large ribosomal subunit	IEP	Predicted GO
MF	GO:0016462	pyrophosphatase activity	IEP	Predicted GO
MF	GO:0016651	oxidoreductase activity, acting on NAD(P)H	IEP	Predicted GO
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	IEP	Predicted GO
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	IEP	Predicted GO
MF	GO:0017111	nucleoside-triphosphatase activity	IEP	Predicted GO
MF	GO:0019001	guanyl nucleotide binding	IEP	Predicted GO
BP	GO:0022900	electron transport chain	IEP	Predicted GO
MF	GO:0032549	ribonucleoside binding	IEP	Predicted GO
MF	GO:0032550	purine ribonucleoside binding	IEP	Predicted GO
MF	GO:0032561	guanyl ribonucleotide binding	IEP	Predicted GO
CC	GO:0032991	protein-containing complex	IEP	Predicted GO
BP	GO:0034645	cellular macromolecule biosynthetic process	IEP	Predicted GO
BP	GO:0043043	peptide biosynthetic process	IEP	Predicted GO
BP	GO:0043603	cellular amide metabolic process	IEP	Predicted GO
BP	GO:0043604	amide biosynthetic process	IEP	Predicted GO
CC	GO:0044391	ribosomal subunit	IEP	Predicted GO
CC	GO:0044424	intracellular part	IEP	Predicted GO
CC	GO:0044444	cytoplasmic part	IEP	Predicted GO
CC	GO:0044464	cell part	IEP	Predicted GO
BP	GO:0051603	proteolysis involved in cellular protein catabolic process	IEP	Predicted GO
MF	GO:0070003	threonine-type peptidase activity	IEP	Predicted GO
CC	GO:1990904	ribonucleoprotein complex	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR003959	ATPase_AAA_core	3	46

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PSME_00006889-RA

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation