PSME_00011005-RA

Description : (at2g31660 : 1342.0) SAD2 (super sensitive to ABA and drought 2) encodes an importin beta-domain family protein likely to be involved in nuclear transport in ABA signaling. Subcellular localization of GFP-tagged SAD2 showed a predominantly nuclear localization, consistent with a role for SAD2 in nuclear transport. Mutation of SAD2 in Arabidopsis alters abscisic acid sensitivity. SAD2 was ubiquitously expressed at low levels in all tissues except flowers. SAD2 expression was not induced by ABA or stress. Loss of function mutations in SAD2 exhibit increased tolerance for UV stress, increased production of UV protective secondary metabolites and suppression of nuclear localization of MYB4 (a repressor of UV stress response genes).; SUPER SENSITIVE TO ABA AND DROUGHT2 (SAD2); FUNCTIONS IN: protein transporter activity, binding; INVOLVED IN: protein import into nucleus, docking, protein import into nucleus; LOCATED IN: nucleus, nuclear pore, cytoplasm; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Importin-beta, N-terminal (InterPro:IPR001494), Armadillo-like helical (InterPro:IPR011989), Armadillo-type fold (InterPro:IPR016024), Exportin/Importin, Cse1-like (InterPro:IPR013713); BEST Arabidopsis thaliana protein match is: ARM repeat superfamily protein (TAIR:AT3G59020.1); Has 3689 Blast hits to 2792 proteins in 293 species: Archae - 3; Bacteria - 183; Metazoa - 1271; Fungi - 834; Plants - 368; Viruses - 60; Other Eukaryotes - 970 (source: NCBI BLink). & (reliability: 2684.0) & (original description: no original description)

Gene families : OG_42_0003831 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0003831_tree

Sequence : coding (download), protein (download)

Download

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pseudotsuga release: PSME_00011005-RA
Cluster	HCCA clusters: Cluster_194

Target	Alias	Description	ECC score	Gene Family Method	Actions
Bradi3g43400	No alias	ARM repeat superfamily protein	0.03	Orthogroups_2024-Update
Pp1s271_27V6	No alias	T9H9.18; importin beta-2 subunit family protein...	0.03	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005515	protein binding	None	Extended
BP	GO:0006810	transport	None	Extended
BP	GO:0006886	intracellular protein transport	IEA	InterProScan predictions
BP	GO:0008104	protein localization	None	Extended
BP	GO:0008150	biological_process	None	Extended
MF	GO:0008536	Ran GTPase binding	IEA	InterProScan predictions
BP	GO:0015031	protein transport	None	Extended
BP	GO:0015833	peptide transport	None	Extended
MF	GO:0017016	Ras GTPase binding	None	Extended
MF	GO:0019899	enzyme binding	None	Extended
MF	GO:0031267	small GTPase binding	None	Extended
BP	GO:0033036	macromolecule localization	None	Extended
BP	GO:0042886	amide transport	None	Extended
BP	GO:0045184	establishment of protein localization	None	Extended
BP	GO:0046907	intracellular transport	None	Extended
MF	GO:0051020	GTPase binding	None	Extended
BP	GO:0051179	localization	None	Extended
BP	GO:0051234	establishment of localization	None	Extended
BP	GO:0051641	cellular localization	None	Extended
BP	GO:0051649	establishment of localization in cell	None	Extended
BP	GO:0071702	organic substance transport	None	Extended
BP	GO:0071705	nitrogen compound transport	None	Extended

Toggle parental

Type	GO Term	Name	Evidence	Source
CC	GO:0000159	protein phosphatase type 2A complex	IEP	Predicted GO
MF	GO:0000166	nucleotide binding	IEP	Predicted GO
BP	GO:0002097	tRNA wobble base modification	IEP	Predicted GO
BP	GO:0002098	tRNA wobble uridine modification	IEP	Predicted GO
MF	GO:0003676	nucleic acid binding	IEP	Predicted GO
MF	GO:0003682	chromatin binding	IEP	Predicted GO
MF	GO:0003723	RNA binding	IEP	Predicted GO
MF	GO:0003950	NAD+ ADP-ribosyltransferase activity	IEP	Predicted GO
MF	GO:0003980	UDP-glucose:glycoprotein glucosyltransferase activity	IEP	Predicted GO
MF	GO:0003989	acetyl-CoA carboxylase activity	IEP	Predicted GO
MF	GO:0004427	inorganic diphosphatase activity	IEP	Predicted GO
MF	GO:0004611	phosphoenolpyruvate carboxykinase activity	IEP	Predicted GO
MF	GO:0004809	tRNA (guanine-N2-)-methyltransferase activity	IEP	Predicted GO
MF	GO:0004842	ubiquitin-protein transferase activity	IEP	Predicted GO
MF	GO:0005524	ATP binding	IEP	Predicted GO
BP	GO:0006082	organic acid metabolic process	IEP	Predicted GO
BP	GO:0006099	tricarboxylic acid cycle	IEP	Predicted GO
BP	GO:0006101	citrate metabolic process	IEP	Predicted GO
BP	GO:0006139	nucleobase-containing compound metabolic process	IEP	Predicted GO
BP	GO:0006325	chromatin organization	IEP	Predicted GO
BP	GO:0006338	chromatin remodeling	IEP	Predicted GO
BP	GO:0006354	DNA-templated transcription, elongation	IEP	Predicted GO
BP	GO:0006368	transcription elongation from RNA polymerase II promoter	IEP	Predicted GO
BP	GO:0006396	RNA processing	IEP	Predicted GO
BP	GO:0006399	tRNA metabolic process	IEP	Predicted GO
BP	GO:0006400	tRNA modification	IEP	Predicted GO
BP	GO:0006464	cellular protein modification process	IEP	Predicted GO
BP	GO:0006473	protein acetylation	IEP	Predicted GO
BP	GO:0006475	internal protein amino acid acetylation	IEP	Predicted GO
BP	GO:0006725	cellular aromatic compound metabolic process	IEP	Predicted GO
BP	GO:0006807	nitrogen compound metabolic process	IEP	Predicted GO
BP	GO:0006888	ER to Golgi vesicle-mediated transport	IEP	Predicted GO
CC	GO:0008023	transcription elongation factor complex	IEP	Predicted GO
BP	GO:0008033	tRNA processing	IEP	Predicted GO
MF	GO:0008144	drug binding	IEP	Predicted GO
MF	GO:0008170	N-methyltransferase activity	IEP	Predicted GO
MF	GO:0008175	tRNA methyltransferase activity	IEP	Predicted GO
MF	GO:0008234	cysteine-type peptidase activity	IEP	Predicted GO
CC	GO:0008287	protein serine/threonine phosphatase complex	IEP	Predicted GO
MF	GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	IEP	Predicted GO
MF	GO:0008964	phosphoenolpyruvate carboxylase activity	IEP	Predicted GO
CC	GO:0009317	acetyl-CoA carboxylase complex	IEP	Predicted GO
BP	GO:0009451	RNA modification	IEP	Predicted GO
MF	GO:0009678	hydrogen-translocating pyrophosphatase activity	IEP	Predicted GO
BP	GO:0009987	cellular process	IEP	Predicted GO
MF	GO:0015399	primary active transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015405	P-P-bond-hydrolysis-driven transmembrane transporter activity	IEP	Predicted GO
BP	GO:0015977	carbon fixation	IEP	Predicted GO
BP	GO:0016070	RNA metabolic process	IEP	Predicted GO
BP	GO:0016192	vesicle-mediated transport	IEP	Predicted GO
BP	GO:0016197	endosomal transport	IEP	Predicted GO
MF	GO:0016421	CoA carboxylase activity	IEP	Predicted GO
MF	GO:0016423	tRNA (guanine) methyltransferase activity	IEP	Predicted GO
MF	GO:0016462	pyrophosphatase activity	IEP	Predicted GO
BP	GO:0016482	cytosolic transport	IEP	Predicted GO
BP	GO:0016569	covalent chromatin modification	IEP	Predicted GO
BP	GO:0016570	histone modification	IEP	Predicted GO
BP	GO:0016573	histone acetylation	IEP	Predicted GO
BP	GO:0016579	protein deubiquitination	IEP	Predicted GO
CC	GO:0016593	Cdc73/Paf1 complex	IEP	Predicted GO
MF	GO:0016763	transferase activity, transferring pentosyl groups	IEP	Predicted GO
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	IEP	Predicted GO
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	IEP	Predicted GO
MF	GO:0016830	carbon-carbon lyase activity	IEP	Predicted GO
MF	GO:0016831	carboxy-lyase activity	IEP	Predicted GO
MF	GO:0016885	ligase activity, forming carbon-carbon bonds	IEP	Predicted GO
BP	GO:0016999	antibiotic metabolic process	IEP	Predicted GO
MF	GO:0017069	snRNA binding	IEP	Predicted GO
MF	GO:0017070	U6 snRNA binding	IEP	Predicted GO
MF	GO:0017076	purine nucleotide binding	IEP	Predicted GO
BP	GO:0018205	peptidyl-lysine modification	IEP	Predicted GO
BP	GO:0018393	internal peptidyl-lysine acetylation	IEP	Predicted GO
BP	GO:0018394	peptidyl-lysine acetylation	IEP	Predicted GO
MF	GO:0019208	phosphatase regulator activity	IEP	Predicted GO
BP	GO:0019752	carboxylic acid metabolic process	IEP	Predicted GO
MF	GO:0019783	ubiquitin-like protein-specific protease activity	IEP	Predicted GO
MF	GO:0019787	ubiquitin-like protein transferase activity	IEP	Predicted GO
MF	GO:0019888	protein phosphatase regulator activity	IEP	Predicted GO
CC	GO:0030117	membrane coat	IEP	Predicted GO
CC	GO:0030120	vesicle coat	IEP	Predicted GO
CC	GO:0030127	COPII vesicle coat	IEP	Predicted GO
MF	GO:0030554	adenyl nucleotide binding	IEP	Predicted GO
MF	GO:0030623	U5 snRNA binding	IEP	Predicted GO
CC	GO:0030906	retromer, cargo-selective complex	IEP	Predicted GO
MF	GO:0031491	nucleosome binding	IEP	Predicted GO
MF	GO:0032553	ribonucleotide binding	IEP	Predicted GO
MF	GO:0032555	purine ribonucleotide binding	IEP	Predicted GO
MF	GO:0032559	adenyl ribonucleotide binding	IEP	Predicted GO
BP	GO:0032774	RNA biosynthetic process	IEP	Predicted GO
CC	GO:0032991	protein-containing complex	IEP	Predicted GO
CC	GO:0033588	Elongator holoenzyme complex	IEP	Predicted GO
BP	GO:0034470	ncRNA processing	IEP	Predicted GO
BP	GO:0034641	cellular nitrogen compound metabolic process	IEP	Predicted GO
BP	GO:0034660	ncRNA metabolic process	IEP	Predicted GO
MF	GO:0035639	purine ribonucleoside triphosphate binding	IEP	Predicted GO
MF	GO:0036094	small molecule binding	IEP	Predicted GO
BP	GO:0036211	protein modification process	IEP	Predicted GO
MF	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity	IEP	Predicted GO
BP	GO:0042147	retrograde transport, endosome to Golgi	IEP	Predicted GO
BP	GO:0043044	ATP-dependent chromatin remodeling	IEP	Predicted GO
MF	GO:0043168	anion binding	IEP	Predicted GO
BP	GO:0043170	macromolecule metabolic process	IEP	Predicted GO
BP	GO:0043412	macromolecule modification	IEP	Predicted GO
BP	GO:0043436	oxoacid metabolic process	IEP	Predicted GO
BP	GO:0043543	protein acylation	IEP	Predicted GO
BP	GO:0044237	cellular metabolic process	IEP	Predicted GO
CC	GO:0044424	intracellular part	IEP	Predicted GO
CC	GO:0044433	cytoplasmic vesicle part	IEP	Predicted GO
CC	GO:0044464	cell part	IEP	Predicted GO
MF	GO:0044877	protein-containing complex binding	IEP	Predicted GO
BP	GO:0046483	heterocycle metabolic process	IEP	Predicted GO
BP	GO:0048193	Golgi vesicle transport	IEP	Predicted GO
BP	GO:0070646	protein modification by small protein removal	IEP	Predicted GO
BP	GO:0070647	protein modification by small protein conjugation or removal	IEP	Predicted GO
BP	GO:0072350	tricarboxylic acid metabolic process	IEP	Predicted GO
BP	GO:0090304	nucleic acid metabolic process	IEP	Predicted GO
MF	GO:0097159	organic cyclic compound binding	IEP	Predicted GO
MF	GO:0097367	carbohydrate derivative binding	IEP	Predicted GO
CC	GO:0098796	membrane protein complex	IEP	Predicted GO
MF	GO:0101005	ubiquitinyl hydrolase activity	IEP	Predicted GO
MF	GO:0140098	catalytic activity, acting on RNA	IEP	Predicted GO
MF	GO:0140101	catalytic activity, acting on a tRNA	IEP	Predicted GO
MF	GO:1901265	nucleoside phosphate binding	IEP	Predicted GO
BP	GO:1901360	organic cyclic compound metabolic process	IEP	Predicted GO
MF	GO:1901363	heterocyclic compound binding	IEP	Predicted GO
CC	GO:1902494	catalytic complex	IEP	Predicted GO
CC	GO:1903293	phosphatase complex	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR001494	Importin-beta_N	24	98
IPR013713	XPO2_central	193	449

External Links

No external refs found!

PSME_00011005-RA

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation