PSME_00019346-RA


Description : (at4g26970 : 181.0) Encodes an aconitase that can catalyze the conversion of citrate to isocitrate through a cis-aconitate intermediate, indicating that it may participate in the TCA cycle and other primary metabolic pathways. The protein is believed to accumulate in the mitochondria and the cytosol. It affects CSD2 (At2g28190 - a superoxide dismutase) transcript levels and may play a role in the response to oxidative stress. One member of the family (ACO1 - At35830) was shown to specifically bind to the 5' UTR of CSD2 in vitro.; aconitase 2 (ACO2); FUNCTIONS IN: aconitate hydratase activity, copper ion binding; INVOLVED IN: response to oxidative stress, response to cadmium ion, isocitrate metabolic process, citrate metabolic process; LOCATED IN: cytosol, mitochondrion, chloroplast; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 17 growth stages; CONTAINS InterPro DOMAIN/s: Aconitase family, 4Fe-4S cluster binding site (InterPro:IPR018136), Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha (InterPro:IPR001030), Aconitase A/isopropylmalate dehydratase small subunit, swivel (InterPro:IPR000573), Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 (InterPro:IPR015932), Aconitase/Iron regulatory protein 2/2-methylisocitrate dehydratase (InterPro:IPR015934), Aconitase/3-isopropylmalate dehydratase, swivel (InterPro:IPR015928), Aconitase-like core (InterPro:IPR015937), Aconitase/iron regulatory protein 2 (InterPro:IPR006249), Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 (InterPro:IPR015931); BEST Arabidopsis thaliana protein match is: aconitase 3 (TAIR:AT2G05710.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (p49608|acoc_cucma : 159.0) Aconitate hydratase, cytoplasmic (EC 4.2.1.3) (Citrate hydro-lyase) (Aconitase) - Cucurbita maxima (Pumpkin) (Winter squash) & (reliability: 362.0) & (original description: no original description)


Gene families : OG_42_0001446 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0001446_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00019346-RA
Cluster HCCA clusters: Cluster_194

Target Alias Description ECC score Gene Family Method Actions
Glyma.12G193800 No alias aconitase 3 0.04 Orthogroups_2024-Update
Kfl00440_0040 kfl00440_0040_v1.1 (q6yzx6|acoc_orysa : 1344.0) Putative aconitate... 0.02 Orthogroups_2024-Update
MA_7469g0010 No alias (at2g05710 : 1506.0) Encodes an aconitase that can... 0.04 Orthogroups_2024-Update

Type GO Term Name Evidence Source

No GO annotation available for this sequence

Type GO Term Name Evidence Source
MF GO:0003676 nucleic acid binding IEP Predicted GO
MF GO:0003684 damaged DNA binding IEP Predicted GO
MF GO:0003968 RNA-directed 5'-3' RNA polymerase activity IEP Predicted GO
MF GO:0004559 alpha-mannosidase activity IEP Predicted GO
MF GO:0004576 oligosaccharyl transferase activity IEP Predicted GO
MF GO:0004590 orotidine-5'-phosphate decarboxylase activity IEP Predicted GO
MF GO:0004645 phosphorylase activity IEP Predicted GO
MF GO:0004842 ubiquitin-protein transferase activity IEP Predicted GO
MF GO:0005085 guanyl-nucleotide exchange factor activity IEP Predicted GO
MF GO:0005086 ARF guanyl-nucleotide exchange factor activity IEP Predicted GO
MF GO:0005244 voltage-gated ion channel activity IEP Predicted GO
MF GO:0005247 voltage-gated chloride channel activity IEP Predicted GO
MF GO:0005253 anion channel activity IEP Predicted GO
MF GO:0005254 chloride channel activity IEP Predicted GO
BP GO:0005996 monosaccharide metabolic process IEP Predicted GO
BP GO:0006012 galactose metabolic process IEP Predicted GO
BP GO:0006013 mannose metabolic process IEP Predicted GO
BP GO:0006206 pyrimidine nucleobase metabolic process IEP Predicted GO
BP GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process IEP Predicted GO
BP GO:0006289 nucleotide-excision repair IEP Predicted GO
BP GO:0006357 regulation of transcription by RNA polymerase II IEP Predicted GO
BP GO:0006367 transcription initiation from RNA polymerase II promoter IEP Predicted GO
BP GO:0006810 transport IEP Predicted GO
BP GO:0006821 chloride transport IEP Predicted GO
BP GO:0006886 intracellular protein transport IEP Predicted GO
BP GO:0006888 ER to Golgi vesicle-mediated transport IEP Predicted GO
BP GO:0008104 protein localization IEP Predicted GO
MF GO:0008108 UDP-glucose:hexose-1-phosphate uridylyltransferase activity IEP Predicted GO
MF GO:0008184 glycogen phosphorylase activity IEP Predicted GO
MF GO:0008308 voltage-gated anion channel activity IEP Predicted GO
BP GO:0009112 nucleobase metabolic process IEP Predicted GO
BP GO:0009891 positive regulation of biosynthetic process IEP Predicted GO
BP GO:0009893 positive regulation of metabolic process IEP Predicted GO
BP GO:0009966 regulation of signal transduction IEP Predicted GO
BP GO:0010498 proteasomal protein catabolic process IEP Predicted GO
BP GO:0010557 positive regulation of macromolecule biosynthetic process IEP Predicted GO
BP GO:0010604 positive regulation of macromolecule metabolic process IEP Predicted GO
BP GO:0010628 positive regulation of gene expression IEP Predicted GO
BP GO:0010646 regulation of cell communication IEP Predicted GO
BP GO:0015031 protein transport IEP Predicted GO
MF GO:0015108 chloride transmembrane transporter activity IEP Predicted GO
BP GO:0015833 peptide transport IEP Predicted GO
MF GO:0015923 mannosidase activity IEP Predicted GO
BP GO:0016192 vesicle-mediated transport IEP Predicted GO
MF GO:0016651 oxidoreductase activity, acting on NAD(P)H IEP Predicted GO
MF GO:0016779 nucleotidyltransferase activity IEP Predicted GO
BP GO:0019318 hexose metabolic process IEP Predicted GO
MF GO:0019787 ubiquitin-like protein transferase activity IEP Predicted GO
BP GO:0019856 pyrimidine nucleobase biosynthetic process IEP Predicted GO
MF GO:0019899 enzyme binding IEP Predicted GO
MF GO:0022832 voltage-gated channel activity IEP Predicted GO
BP GO:0023051 regulation of signaling IEP Predicted GO
CC GO:0030117 membrane coat IEP Predicted GO
CC GO:0030118 clathrin coat IEP Predicted GO
CC GO:0030119 AP-type membrane coat adaptor complex IEP Predicted GO
CC GO:0030120 vesicle coat IEP Predicted GO
CC GO:0030125 clathrin vesicle coat IEP Predicted GO
CC GO:0030126 COPI vesicle coat IEP Predicted GO
CC GO:0030127 COPII vesicle coat IEP Predicted GO
CC GO:0030130 clathrin coat of trans-Golgi network vesicle IEP Predicted GO
CC GO:0030131 clathrin adaptor complex IEP Predicted GO
CC GO:0030132 clathrin coat of coated pit IEP Predicted GO
BP GO:0030163 protein catabolic process IEP Predicted GO
MF GO:0030976 thiamine pyrophosphate binding IEP Predicted GO
BP GO:0031325 positive regulation of cellular metabolic process IEP Predicted GO
BP GO:0031328 positive regulation of cellular biosynthetic process IEP Predicted GO
BP GO:0032012 regulation of ARF protein signal transduction IEP Predicted GO
BP GO:0032784 regulation of DNA-templated transcription, elongation IEP Predicted GO
BP GO:0032786 positive regulation of DNA-templated transcription, elongation IEP Predicted GO
BP GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter IEP Predicted GO
BP GO:0033036 macromolecule localization IEP Predicted GO
BP GO:0034243 regulation of transcription elongation from RNA polymerase II promoter IEP Predicted GO
BP GO:0042886 amide transport IEP Predicted GO
BP GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process IEP Predicted GO
CC GO:0044424 intracellular part IEP Predicted GO
CC GO:0044425 membrane part IEP Predicted GO
CC GO:0044431 Golgi apparatus part IEP Predicted GO
CC GO:0044433 cytoplasmic vesicle part IEP Predicted GO
CC GO:0044444 cytoplasmic part IEP Predicted GO
CC GO:0044464 cell part IEP Predicted GO
BP GO:0045184 establishment of protein localization IEP Predicted GO
BP GO:0045893 positive regulation of transcription, DNA-templated IEP Predicted GO
BP GO:0045935 positive regulation of nucleobase-containing compound metabolic process IEP Predicted GO
BP GO:0045944 positive regulation of transcription by RNA polymerase II IEP Predicted GO
BP GO:0046112 nucleobase biosynthetic process IEP Predicted GO
BP GO:0046578 regulation of Ras protein signal transduction IEP Predicted GO
BP GO:0046907 intracellular transport IEP Predicted GO
MF GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer IEP Predicted GO
BP GO:0048518 positive regulation of biological process IEP Predicted GO
BP GO:0048522 positive regulation of cellular process IEP Predicted GO
BP GO:0048583 regulation of response to stimulus IEP Predicted GO
MF GO:0051020 GTPase binding IEP Predicted GO
BP GO:0051056 regulation of small GTPase mediated signal transduction IEP Predicted GO
BP GO:0051173 positive regulation of nitrogen compound metabolic process IEP Predicted GO
BP GO:0051179 localization IEP Predicted GO
BP GO:0051234 establishment of localization IEP Predicted GO
BP GO:0051254 positive regulation of RNA metabolic process IEP Predicted GO
MF GO:0051536 iron-sulfur cluster binding IEP Predicted GO
MF GO:0051540 metal cluster binding IEP Predicted GO
BP GO:0051641 cellular localization IEP Predicted GO
BP GO:0051649 establishment of localization in cell IEP Predicted GO
MF GO:0070569 uridylyltransferase activity IEP Predicted GO
BP GO:0071702 organic substance transport IEP Predicted GO
BP GO:0071705 nitrogen compound transport IEP Predicted GO
BP GO:0072527 pyrimidine-containing compound metabolic process IEP Predicted GO
BP GO:0072528 pyrimidine-containing compound biosynthetic process IEP Predicted GO
CC GO:0098796 membrane protein complex IEP Predicted GO
MF GO:1901681 sulfur compound binding IEP Predicted GO
BP GO:1902531 regulation of intracellular signal transduction IEP Predicted GO
BP GO:1902680 positive regulation of RNA biosynthetic process IEP Predicted GO
BP GO:1903508 positive regulation of nucleic acid-templated transcription IEP Predicted GO

No InterPro domains available for this sequence

No external refs found!