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PSME_00020797-RA


Description : (at1g68760 : 170.0) Encodes a cytosol-localized nudix hydrolase that hydrolyzes 8-oxo-(d)GTP to its monophosphate form. This protective mechanism prevents the misincorporation of these oxidized nucleotides into DNA and RNA. NUDX1 also has a low level of dihydroneopterin triphosphate pyrophosphatase activity in vitro and may participate in the folate synthesis pathway.; nudix hydrolase 1 (NUDX1); FUNCTIONS IN: hydrolase activity, dihydroneopterin triphosphate pyrophosphohydrolase activity, 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity; INVOLVED IN: response to DNA damage stimulus; LOCATED IN: cytosol; EXPRESSED IN: 16 plant structures; EXPRESSED DURING: 10 growth stages; CONTAINS InterPro DOMAIN/s: NUDIX hydrolase domain-like (InterPro:IPR015797), NUDIX hydrolase (InterPro:IPR020476), NUDIX hydrolase, conserved site (InterPro:IPR020084), NUDIX hydrolase domain (InterPro:IPR000086); Has 6319 Blast hits to 6317 proteins in 1575 species: Archae - 191; Bacteria - 5327; Metazoa - 193; Fungi - 66; Plants - 51; Viruses - 14; Other Eukaryotes - 477 (source: NCBI BLink). & (reliability: 340.0) & (original description: no original description)


Gene families : OG_42_0008511 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0008511_tree

Sequence : coding (download), protein (download)


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Type Description Actions
Neighborhood Pseudotsuga release: PSME_00020797-RA
Cluster HCCA clusters: Cluster_169


Type GO Term Name Evidence Source
MF GO:0016787 hydrolase activity IEA InterProScan predictions
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Type GO Term Name Evidence Source
MF GO:0003909 DNA ligase activity IEP Predicted GO
MF GO:0003910 DNA ligase (ATP) activity IEP Predicted GO
MF GO:0004312 fatty acid synthase activity IEP Predicted GO
MF GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity IEP Predicted GO
BP GO:0006310 DNA recombination IEP Predicted GO
BP GO:0006352 DNA-templated transcription, initiation IEP Predicted GO
BP GO:0006633 fatty acid biosynthetic process IEP Predicted GO
BP GO:0006694 steroid biosynthetic process IEP Predicted GO
BP GO:0008202 steroid metabolic process IEP Predicted GO
MF GO:0008378 galactosyltransferase activity IEP Predicted GO
BP GO:0008610 lipid biosynthetic process IEP Predicted GO
MF GO:0016886 ligase activity, forming phosphoric ester bonds IEP Predicted GO
MF GO:0140097 catalytic activity, acting on DNA IEP Predicted GO
BP GO:1901360 organic cyclic compound metabolic process IEP Predicted GO
BP GO:1901362 organic cyclic compound biosynthetic process IEP Predicted GO
InterPro domains Description Start Stop
IPR000086 NUDIX_hydrolase_dom 26 144
No external refs found!