PSME_00030174-RA

Description : (at2g47000 : 1538.0) Multidrug resistance P-glycoprotein (MDR/PGP) subfamily of ABC transporters. Functions in the basipetal redirection of auxin from the root tip. Exhibits apolar plasma membrane localization in the root cap and polar localization in tissues above.; ATP binding cassette subfamily B4 (ABCB4); FUNCTIONS IN: xenobiotic-transporting ATPase activity, ATPase activity, coupled to transmembrane movement of substances; INVOLVED IN: in 8 processes; LOCATED IN: plasma membrane, membrane; EXPRESSED IN: 14 plant structures; EXPRESSED DURING: 4 anthesis, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ABC transporter-like (InterPro:IPR003439), ABC transporter, transmembrane domain, type 1 (InterPro:IPR011527), ABC transporter integral membrane type 1 (InterPro:IPR017940), ABC transporter, transmembrane domain (InterPro:IPR001140), ABC transporter, conserved site (InterPro:IPR017871); BEST Arabidopsis thaliana protein match is: P-glycoprotein 21 (TAIR:AT3G62150.1); Has 844144 Blast hits to 390751 proteins in 4168 species: Archae - 14748; Bacteria - 659498; Metazoa - 17847; Fungi - 13026; Plants - 10001; Viruses - 45; Other Eukaryotes - 128979 (source: NCBI BLink). & (q6yuu5|mdr_orysa : 496.0) Putative multidrug resistance protein (P-glycoprotein) - Oryza sativa (Rice) & (reliability: 3076.0) & (original description: no original description)

Gene families : OG_42_0000040 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000040_tree

Sequence : coding (download), protein (download)

Attention: This gene has low abundance.

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pseudotsuga release: PSME_00030174-RA
Cluster	HCCA clusters: Cluster_150

Target	Alias	Description	ECC score	Gene Family Method
123915	No alias	P-glycoprotein 11	0.04	Orthogroups_2024-Update
176522	No alias	ATP binding cassette subfamily B4	0.02	Orthogroups_2024-Update
408755	No alias	P-glycoprotein 18	0.03	Orthogroups_2024-Update
92485	No alias	ATP binding cassette subfamily B19	0.04	Orthogroups_2024-Update
A4A49_02254	No alias	abc transporter b family member 11	0.03	Orthogroups_2024-Update
At1g10680	No alias	ABC transporter B family member 10...	0.03	Orthogroups_2024-Update
At5g46540	No alias	ABC transporter B family member 7...	0.02	Orthogroups_2024-Update
Bradi2g17710	No alias	P-glycoprotein 11	0.03	Orthogroups_2024-Update
Bradi2g47410	No alias	ATP binding cassette subfamily B4	0.02	Orthogroups_2024-Update
Brara.C01848.1	No alias	Unknown function	0.02	Orthogroups_2024-Update
Brara.D00408.1	No alias	subfamily ABCB transporter	0.06	Orthogroups_2024-Update
Brara.D02245.1	No alias	Unknown function	0.03	Orthogroups_2024-Update
Brara.F03154.1	No alias	subfamily ABCB transporter	0.04	Orthogroups_2024-Update
Brara.I00328.1	No alias	subfamily ABCB transporter	0.04	Orthogroups_2024-Update
GRMZM2G004748	No alias	P-glycoprotein 2	0.02	Orthogroups_2024-Update
GRMZM2G025860	No alias	ABC transporter family protein	0.04	Orthogroups_2024-Update
GRMZM2G085111	No alias	P-glycoprotein 21	0.02	Orthogroups_2024-Update
GRMZM2G085236	No alias	ATP binding cassette subfamily B19	0.02	Orthogroups_2024-Update
GRMZM2G119894	No alias	P-glycoprotein 21	0.03	Orthogroups_2024-Update
GRMZM2G167658	No alias	ATP binding cassette subfamily B19	0.03	Orthogroups_2024-Update
Glyma.10G055000	No alias	ATP binding cassette subfamily B1	0.02	Orthogroups_2024-Update
Glyma.13G118500	No alias	P-glycoprotein 11	0.02	Orthogroups_2024-Update
Glyma.13G222000	No alias	P-glycoprotein 9	0.03	Orthogroups_2024-Update
Glyma.16G078100	No alias	ABC transporter family protein	0.05	Orthogroups_2024-Update
Glyma.17G041200	No alias	P-glycoprotein 11	0.02	Orthogroups_2024-Update
Glyma.17G041300	No alias	ATP binding cassette subfamily B4	0.03	Orthogroups_2024-Update
Glyma.18G012700	No alias	P-glycoprotein 18	0.03	Orthogroups_2024-Update
HORVU3Hr1G065240.1	No alias	subfamily ABCB transporter	0.03	Orthogroups_2024-Update
LOC_Os01g29870	No alias	multidrug resistance protein 9, putative, expressed	0.02	Orthogroups_2024-Update
LOC_Os03g17180	No alias	ABC transporter, ATP-binding protein, putative, expressed	0.02	Orthogroups_2024-Update
PSME_00001910-RA	No alias	(at3g28345 : 1399.0) ABC transporter family protein;...	0.03	Orthogroups_2024-Update
PSME_00004142-RA	No alias	(q6yuu5\|mdr_orysa : 1178.0) Putative multidrug...	0.02	Orthogroups_2024-Update
PSME_00011041-RA	No alias	(at4g25960 : 1546.0) P-glycoprotein 2 (PGP2); FUNCTIONS...	0.05	Orthogroups_2024-Update
PSME_00023263-RA	No alias	(q6yuu5\|mdr_orysa : 1044.0) Putative multidrug...	0.05	Orthogroups_2024-Update
PSME_00037351-RA	No alias	(at3g28345 : 1429.0) ABC transporter family protein;...	0.04	Orthogroups_2024-Update
PSME_00039058-RA	No alias	(q6yuu5\|mdr_orysa : 1225.0) Putative multidrug...	0.07	Orthogroups_2024-Update
Potri.001G165000	No alias	ATP binding cassette subfamily B19	0.03	Orthogroups_2024-Update
Potri.002G019600	No alias	P-glycoprotein 13	0.03	Orthogroups_2024-Update
Potri.003G094400	No alias	P-glycoprotein 2	0.04	Orthogroups_2024-Update
Potri.014G113000	No alias	ATP binding cassette subfamily B4	0.02	Orthogroups_2024-Update
Potri.014G113500	No alias	P-glycoprotein 21	0.03	Orthogroups_2024-Update
Potri.017G081100	No alias	ATP binding cassette subfamily B19	0.03	Orthogroups_2024-Update
Potri.017G085000	No alias	ABC transporter family protein	0.03	Orthogroups_2024-Update
Potri.018G141300	No alias	ABC transporter family protein	0.02	Orthogroups_2024-Update
Potri.018G141400	No alias	ABC transporter family protein	0.03	Orthogroups_2024-Update
Seita.1G280600.1	No alias	subfamily ABCB transporter	0.03	Orthogroups_2024-Update
Seita.5G283600.1	No alias	subfamily ABCB transporter	0.03	Orthogroups_2024-Update
Sobic.003G267700.1	No alias	subfamily ABCB transporter	0.03	Orthogroups_2024-Update
Sobic.006G014800.1	No alias	ABC-B-type transporter *(AMN3) & subfamily ABCB transporter	0.03	Orthogroups_2024-Update
Sobic.006G236700.1	No alias	auxin efflux transporter *(ABCB19) & subfamily ABCB transporter	0.02	Orthogroups_2024-Update
Solyc03g005860	No alias	ABC transporter B family protein (AHRD V3.3 *** G7ILW7_MEDTR)	0.03	Orthogroups_2024-Update
Solyc03g093650	No alias	ABC transporter B family protein (AHRD V3.3 *** A0A072UBK0_MEDTR)	0.03	Orthogroups_2024-Update
Solyc06g009280	No alias	ABC transporter B family protein (AHRD V3.3 *** G7IBR0_MEDTR)	0.04	Orthogroups_2024-Update
Solyc06g009290	No alias	ABC transporter B family protein (AHRD V3.3 *** G7IBR0_MEDTR)	0.02	Orthogroups_2024-Update
Solyc09g008240	No alias	ABC transporter B family protein (AHRD V3.3 *** G7L3V6_MEDTR)	0.03	Orthogroups_2024-Update
Sopen03g040850	No alias	ABC transporter transmembrane region	0.02	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0005215	transporter activity	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	InterProScan predictions
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0006810	transport	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
MF	GO:0015399	primary active transmembrane transporter activity	None	Extended
MF	GO:0015405	P-P-bond-hydrolysis-driven transmembrane transporter activity	None	Extended
CC	GO:0016021	integral component of membrane	IEA	InterProScan predictions
MF	GO:0016462	pyrophosphatase activity	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	None	Extended
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	None	Extended
MF	GO:0016887	ATPase activity	IEA	InterProScan predictions
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0017111	nucleoside-triphosphatase activity	None	Extended
MF	GO:0022804	active transmembrane transporter activity	None	Extended
MF	GO:0022857	transmembrane transporter activity	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
CC	GO:0031224	intrinsic component of membrane	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0042623	ATPase activity, coupled	None	Extended
MF	GO:0042626	ATPase activity, coupled to transmembrane movement of substances	IEA	InterProScan predictions
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
MF	GO:0043492	ATPase activity, coupled to movement of substances	None	Extended
CC	GO:0044425	membrane part	None	Extended
BP	GO:0051179	localization	None	Extended
BP	GO:0051234	establishment of localization	None	Extended
BP	GO:0055085	transmembrane transport	IEA	InterProScan predictions
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000287	magnesium ion binding	IEP	Predicted GO
MF	GO:0004478	methionine adenosyltransferase activity	IEP	Predicted GO
MF	GO:0004559	alpha-mannosidase activity	IEP	Predicted GO
MF	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity	IEP	Predicted GO
MF	GO:0004612	phosphoenolpyruvate carboxykinase (ATP) activity	IEP	Predicted GO
MF	GO:0004672	protein kinase activity	IEP	Predicted GO
CC	GO:0005667	transcription factor complex	IEP	Predicted GO
CC	GO:0005672	transcription factor TFIIA complex	IEP	Predicted GO
BP	GO:0006094	gluconeogenesis	IEP	Predicted GO
BP	GO:0006367	transcription initiation from RNA polymerase II promoter	IEP	Predicted GO
BP	GO:0006464	cellular protein modification process	IEP	Predicted GO
BP	GO:0006468	protein phosphorylation	IEP	Predicted GO
BP	GO:0006556	S-adenosylmethionine biosynthetic process	IEP	Predicted GO
BP	GO:0006790	sulfur compound metabolic process	IEP	Predicted GO
BP	GO:0006820	anion transport	IEP	Predicted GO
BP	GO:0006835	dicarboxylic acid transport	IEP	Predicted GO
BP	GO:0008152	metabolic process	IEP	Predicted GO
BP	GO:0009690	cytokinin metabolic process	IEP	Predicted GO
MF	GO:0010333	terpene synthase activity	IEP	Predicted GO
BP	GO:0010817	regulation of hormone levels	IEP	Predicted GO
BP	GO:0015711	organic anion transport	IEP	Predicted GO
BP	GO:0015740	C4-dicarboxylate transport	IEP	Predicted GO
BP	GO:0015743	malate transport	IEP	Predicted GO
BP	GO:0015849	organic acid transport	IEP	Predicted GO
MF	GO:0015923	mannosidase activity	IEP	Predicted GO
MF	GO:0015924	mannosyl-oligosaccharide mannosidase activity	IEP	Predicted GO
MF	GO:0016301	kinase activity	IEP	Predicted GO
BP	GO:0016310	phosphorylation	IEP	Predicted GO
MF	GO:0016491	oxidoreductase activity	IEP	Predicted GO
MF	GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	IEP	Predicted GO
MF	GO:0016651	oxidoreductase activity, acting on NAD(P)H	IEP	Predicted GO
MF	GO:0016773	phosphotransferase activity, alcohol group as acceptor	IEP	Predicted GO
MF	GO:0016829	lyase activity	IEP	Predicted GO
MF	GO:0016838	carbon-oxygen lyase activity, acting on phosphates	IEP	Predicted GO
MF	GO:0019139	cytokinin dehydrogenase activity	IEP	Predicted GO
BP	GO:0019319	hexose biosynthetic process	IEP	Predicted GO
BP	GO:0034754	cellular hormone metabolic process	IEP	Predicted GO
BP	GO:0036211	protein modification process	IEP	Predicted GO
BP	GO:0042445	hormone metabolic process	IEP	Predicted GO
BP	GO:0043412	macromolecule modification	IEP	Predicted GO
BP	GO:0044238	primary metabolic process	IEP	Predicted GO
BP	GO:0044272	sulfur compound biosynthetic process	IEP	Predicted GO
CC	GO:0044798	nuclear transcription factor complex	IEP	Predicted GO
BP	GO:0046364	monosaccharide biosynthetic process	IEP	Predicted GO
BP	GO:0046500	S-adenosylmethionine metabolic process	IEP	Predicted GO
BP	GO:0046942	carboxylic acid transport	IEP	Predicted GO
MF	GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	IEP	Predicted GO
BP	GO:0071704	organic substance metabolic process	IEP	Predicted GO
CC	GO:0090575	RNA polymerase II transcription factor complex	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR011527	ABC1_TM_dom	72	344
IPR011527	ABC1_TM_dom	753	1025
IPR003439	ABC_transporter-like	414	561
IPR003439	ABC_transporter-like	1093	1242

External Links

No external refs found!

PSME_00030174-RA

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation