Description : (at2g31660 : 235.0) SAD2 (super sensitive to ABA and drought 2) encodes an importin beta-domain family protein likely to be involved in nuclear transport in ABA signaling. Subcellular localization of GFP-tagged SAD2 showed a predominantly nuclear localization, consistent with a role for SAD2 in nuclear transport. Mutation of SAD2 in Arabidopsis alters abscisic acid sensitivity. SAD2 was ubiquitously expressed at low levels in all tissues except flowers. SAD2 expression was not induced by ABA or stress. Loss of function mutations in SAD2 exhibit increased tolerance for UV stress, increased production of UV protective secondary metabolites and suppression of nuclear localization of MYB4 (a repressor of UV stress response genes).; SUPER SENSITIVE TO ABA AND DROUGHT2 (SAD2); FUNCTIONS IN: protein transporter activity, binding; INVOLVED IN: protein import into nucleus, docking, protein import into nucleus; LOCATED IN: nucleus, nuclear pore, cytoplasm; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Importin-beta, N-terminal (InterPro:IPR001494), Armadillo-like helical (InterPro:IPR011989), Armadillo-type fold (InterPro:IPR016024), Exportin/Importin, Cse1-like (InterPro:IPR013713); BEST Arabidopsis thaliana protein match is: ARM repeat superfamily protein (TAIR:AT3G59020.1); Has 3689 Blast hits to 2792 proteins in 293 species: Archae - 3; Bacteria - 183; Metazoa - 1271; Fungi - 834; Plants - 368; Viruses - 60; Other Eukaryotes - 970 (source: NCBI BLink). & (reliability: 470.0) & (original description: no original description)
Gene families : OG_42_0003956 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0003956_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
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Neighborhood | Pseudotsuga release: PSME_00033038-RA | |
Cluster | HCCA clusters: Cluster_10 |
Type | GO Term | Name | Evidence | Source |
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No GO annotation available for this sequence |
Type | GO Term | Name | Evidence | Source |
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BP | GO:0006298 | mismatch repair | IEP | Predicted GO |
MF | GO:0016701 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen | IEP | Predicted GO |
MF | GO:0016702 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen | IEP | Predicted GO |
MF | GO:0030983 | mismatched DNA binding | IEP | Predicted GO |
MF | GO:0051213 | dioxygenase activity | IEP | Predicted GO |
No InterPro domains available for this sequence
No external refs found! |