PSME_00038116-RA


Description : (at5g23450 : 741.0) Encodes a sphingosine kinase that specifically phosphorylates D-erythro-dihydrosphingosine (DHS), but not N-acetyl-DHS or D-threo-DHS. It also also phosphorylates D-erythro-sphingosine, trans-4, trans-8-sphingadienine and phytosphingosine.; long-chain base (LCB) kinase 1 (LCBK1); FUNCTIONS IN: diacylglycerol kinase activity, D-erythro-sphingosine kinase activity; INVOLVED IN: activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway, sphingolipid biosynthetic process; LOCATED IN: plasma membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Diacylglycerol kinase, catalytic domain (InterPro:IPR001206); BEST Arabidopsis thaliana protein match is: sphingosine kinase 1 (TAIR:AT4G21540.1); Has 1850 Blast hits to 1642 proteins in 445 species: Archae - 2; Bacteria - 669; Metazoa - 552; Fungi - 144; Plants - 247; Viruses - 0; Other Eukaryotes - 236 (source: NCBI BLink). & (reliability: 1482.0) & (original description: no original description)


Gene families : OG_42_0002783 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0002783_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00038116-RA
Cluster HCCA clusters: Cluster_168

Target Alias Description ECC score Gene Family Method Actions
Bradi5g17160 No alias long-chain base (LCB) kinase 1 0.03 Orthogroups_2024-Update
Brara.F02587.1 No alias sphingoid long-chain base kinase *(LCBK1) & EC_2.7... 0.03 Orthogroups_2024-Update
Sobic.006G163800.1 No alias sphingoid long-chain base kinase *(LCBK1) & EC_2.7... 0.02 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0016301 kinase activity IEA InterProScan predictions
Type GO Term Name Evidence Source
CC GO:0000159 protein phosphatase type 2A complex IEP Predicted GO
MF GO:0004674 protein serine/threonine kinase activity IEP Predicted GO
MF GO:0005543 phospholipid binding IEP Predicted GO
BP GO:0006325 chromatin organization IEP Predicted GO
BP GO:0006355 regulation of transcription, DNA-templated IEP Predicted GO
BP GO:0006473 protein acetylation IEP Predicted GO
BP GO:0006475 internal protein amino acid acetylation IEP Predicted GO
BP GO:0006479 protein methylation IEP Predicted GO
MF GO:0008170 N-methyltransferase activity IEP Predicted GO
BP GO:0008213 protein alkylation IEP Predicted GO
MF GO:0008276 protein methyltransferase activity IEP Predicted GO
CC GO:0008287 protein serine/threonine phosphatase complex IEP Predicted GO
MF GO:0008289 lipid binding IEP Predicted GO
MF GO:0008408 3'-5' exonuclease activity IEP Predicted GO
MF GO:0008757 S-adenosylmethionine-dependent methyltransferase activity IEP Predicted GO
BP GO:0009889 regulation of biosynthetic process IEP Predicted GO
BP GO:0010468 regulation of gene expression IEP Predicted GO
BP GO:0010556 regulation of macromolecule biosynthetic process IEP Predicted GO
MF GO:0016278 lysine N-methyltransferase activity IEP Predicted GO
MF GO:0016279 protein-lysine N-methyltransferase activity IEP Predicted GO
BP GO:0016569 covalent chromatin modification IEP Predicted GO
BP GO:0016570 histone modification IEP Predicted GO
BP GO:0016571 histone methylation IEP Predicted GO
BP GO:0016573 histone acetylation IEP Predicted GO
BP GO:0018022 peptidyl-lysine methylation IEP Predicted GO
MF GO:0018024 histone-lysine N-methyltransferase activity IEP Predicted GO
BP GO:0018193 peptidyl-amino acid modification IEP Predicted GO
BP GO:0018205 peptidyl-lysine modification IEP Predicted GO
BP GO:0018393 internal peptidyl-lysine acetylation IEP Predicted GO
BP GO:0018394 peptidyl-lysine acetylation IEP Predicted GO
MF GO:0019208 phosphatase regulator activity IEP Predicted GO
BP GO:0019219 regulation of nucleobase-containing compound metabolic process IEP Predicted GO
BP GO:0019222 regulation of metabolic process IEP Predicted GO
MF GO:0019888 protein phosphatase regulator activity IEP Predicted GO
BP GO:0031323 regulation of cellular metabolic process IEP Predicted GO
BP GO:0031326 regulation of cellular biosynthetic process IEP Predicted GO
BP GO:0032259 methylation IEP Predicted GO
BP GO:0034968 histone lysine methylation IEP Predicted GO
MF GO:0035091 phosphatidylinositol binding IEP Predicted GO
MF GO:0042054 histone methyltransferase activity IEP Predicted GO
BP GO:0043414 macromolecule methylation IEP Predicted GO
BP GO:0043543 protein acylation IEP Predicted GO
MF GO:0044877 protein-containing complex binding IEP Predicted GO
BP GO:0050789 regulation of biological process IEP Predicted GO
BP GO:0050794 regulation of cellular process IEP Predicted GO
BP GO:0051171 regulation of nitrogen compound metabolic process IEP Predicted GO
BP GO:0051252 regulation of RNA metabolic process IEP Predicted GO
BP GO:0060255 regulation of macromolecule metabolic process IEP Predicted GO
MF GO:0061630 ubiquitin protein ligase activity IEP Predicted GO
MF GO:0061659 ubiquitin-like protein ligase activity IEP Predicted GO
BP GO:0065007 biological regulation IEP Predicted GO
BP GO:0080090 regulation of primary metabolic process IEP Predicted GO
CC GO:1903293 phosphatase complex IEP Predicted GO
BP GO:1903506 regulation of nucleic acid-templated transcription IEP Predicted GO
BP GO:2000112 regulation of cellular macromolecule biosynthetic process IEP Predicted GO
MF GO:2001070 starch binding IEP Predicted GO
BP GO:2001141 regulation of RNA biosynthetic process IEP Predicted GO
InterPro domains Description Start Stop
IPR001206 Diacylglycerol_kinase_cat_dom 248 377
No external refs found!