PSME_00043455-RA


Description : (at3g24495 : 184.0) encodes a DNA mismatch repair homolog of human MutS gene, MSH6. There are four MutS genes in Arabidopsis, MSH2, MSH3, MSH6, and MSH7, which all act as heterodimers and bind to 51-mer duplexes. MSH2*MSH7 exhibit moderate affinity for a (T/G) substrate and weak binding of (+T), suggesting MSH2*MSH7 may be specialized for lesions/base mispairs not tested or for (T/G) mispairs in special contexts.; MUTS homolog 7 (MSH7); FUNCTIONS IN: damaged DNA binding, mismatched DNA binding, ATP binding; INVOLVED IN: mismatch repair; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: DNA mismatch repair protein MutS, connector (InterPro:IPR007860), DNA mismatch repair protein MutS, N-terminal (InterPro:IPR016151), DNA mismatch repair protein MutS, core (InterPro:IPR007696), DNA mismatch repair protein MutS, C-terminal (InterPro:IPR000432), DNA mismatch repair protein MutS-homologue MSH6 (InterPro:IPR015536), DNA mismatch repair protein MutS-like, N-terminal (InterPro:IPR007695); BEST Arabidopsis thaliana protein match is: MUTS homolog 6 (TAIR:AT4G02070.2); Has 17871 Blast hits to 13835 proteins in 2667 species: Archae - 197; Bacteria - 11731; Metazoa - 1028; Fungi - 1274; Plants - 566; Viruses - 3; Other Eukaryotes - 3072 (source: NCBI BLink). & (reliability: 368.0) & (original description: no original description)


Gene families : OG_42_0001047 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0001047_tree

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00043455-RA
Cluster HCCA clusters: Cluster_137

Target Alias Description ECC score Gene Family Method Actions
Seita.5G128200.1 No alias component *(MSH7) of MSH2-x mismatch repair heterodimers 0.01 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0005524 ATP binding IEA InterProScan predictions
BP GO:0006298 mismatch repair IEA InterProScan predictions
MF GO:0030983 mismatched DNA binding IEA InterProScan predictions
Type GO Term Name Evidence Source
MF GO:0000155 phosphorelay sensor kinase activity IEP Predicted GO
MF GO:0004126 cytidine deaminase activity IEP Predicted GO
MF GO:0004673 protein histidine kinase activity IEP Predicted GO
CC GO:0005789 endoplasmic reticulum membrane IEP Predicted GO
BP GO:0006213 pyrimidine nucleoside metabolic process IEP Predicted GO
BP GO:0006216 cytidine catabolic process IEP Predicted GO
BP GO:0006464 cellular protein modification process IEP Predicted GO
BP GO:0006497 protein lipidation IEP Predicted GO
BP GO:0006505 GPI anchor metabolic process IEP Predicted GO
BP GO:0006506 GPI anchor biosynthetic process IEP Predicted GO
BP GO:0006629 lipid metabolic process IEP Predicted GO
BP GO:0006643 membrane lipid metabolic process IEP Predicted GO
BP GO:0006661 phosphatidylinositol biosynthetic process IEP Predicted GO
BP GO:0006664 glycolipid metabolic process IEP Predicted GO
BP GO:0007165 signal transduction IEP Predicted GO
MF GO:0008168 methyltransferase activity IEP Predicted GO
MF GO:0008234 cysteine-type peptidase activity IEP Predicted GO
BP GO:0008610 lipid biosynthetic process IEP Predicted GO
BP GO:0009116 nucleoside metabolic process IEP Predicted GO
BP GO:0009164 nucleoside catabolic process IEP Predicted GO
BP GO:0009247 glycolipid biosynthetic process IEP Predicted GO
BP GO:0009314 response to radiation IEP Predicted GO
BP GO:0009416 response to light stimulus IEP Predicted GO
BP GO:0009581 detection of external stimulus IEP Predicted GO
BP GO:0009582 detection of abiotic stimulus IEP Predicted GO
BP GO:0009583 detection of light stimulus IEP Predicted GO
BP GO:0009584 detection of visible light IEP Predicted GO
BP GO:0009605 response to external stimulus IEP Predicted GO
BP GO:0009972 cytidine deamination IEP Predicted GO
MF GO:0016740 transferase activity IEP Predicted GO
MF GO:0016741 transferase activity, transferring one-carbon groups IEP Predicted GO
MF GO:0016775 phosphotransferase activity, nitrogenous group as acceptor IEP Predicted GO
BP GO:0018298 protein-chromophore linkage IEP Predicted GO
BP GO:0034656 nucleobase-containing small molecule catabolic process IEP Predicted GO
BP GO:0036211 protein modification process IEP Predicted GO
BP GO:0042454 ribonucleoside catabolic process IEP Predicted GO
BP GO:0043412 macromolecule modification IEP Predicted GO
BP GO:0046087 cytidine metabolic process IEP Predicted GO
BP GO:0046131 pyrimidine ribonucleoside metabolic process IEP Predicted GO
BP GO:0046133 pyrimidine ribonucleoside catabolic process IEP Predicted GO
BP GO:0046135 pyrimidine nucleoside catabolic process IEP Predicted GO
BP GO:0046467 membrane lipid biosynthetic process IEP Predicted GO
BP GO:0046474 glycerophospholipid biosynthetic process IEP Predicted GO
BP GO:0051606 detection of stimulus IEP Predicted GO
BP GO:0072529 pyrimidine-containing compound catabolic process IEP Predicted GO
BP GO:1901135 carbohydrate derivative metabolic process IEP Predicted GO
BP GO:1901136 carbohydrate derivative catabolic process IEP Predicted GO
BP GO:1901564 organonitrogen compound metabolic process IEP Predicted GO
BP GO:1901565 organonitrogen compound catabolic process IEP Predicted GO
BP GO:1901657 glycosyl compound metabolic process IEP Predicted GO
BP GO:1901658 glycosyl compound catabolic process IEP Predicted GO
BP GO:1903509 liposaccharide metabolic process IEP Predicted GO
InterPro domains Description Start Stop
IPR000432 DNA_mismatch_repair_MutS_C 197 258
No external refs found!