Description : (at1g26700 : 235.0) A member of a large family of seven-transmembrane domain proteins specific to plants, homologs of the barley mildew resistance locus o (MLO) protein. The Arabidopsis genome contains 15 genes encoding MLO proteins, with localization in plasma membrane. Phylogenetic analysis revealed four clades of closely-related AtMLO genes. ATMLO14 belongs to the clade I, with AtMLO4 and AtMLO11. The gene is expressed during early seedling growth, in developing primary root, and particularly in root tips of 10-day old seedlings; it was not expressed in leaves or flowers, as shown by GUS activity patterns. The expression of several phylogenetically closely-related AtMLO genes showed similar or overlapping tissue specificity and analogous responsiveness to external stimuli, suggesting functional redundancy, co-function, or antagonistic function(s).; MILDEW RESISTANCE LOCUS O 14 (MLO14); FUNCTIONS IN: calmodulin binding; INVOLVED IN: cell death, defense response; LOCATED IN: integral to membrane, plasma membrane; EXPRESSED IN: 12 plant structures; EXPRESSED DURING: 4 anthesis, LP.10 ten leaves visible, F mature embryo stage, 4 leaf senescence stage, LP.08 eight leaves visible; CONTAINS InterPro DOMAIN/s: Mlo-related protein (InterPro:IPR004326); BEST Arabidopsis thaliana protein match is: Seven transmembrane MLO family protein (TAIR:AT5G53760.2); Has 532 Blast hits to 521 proteins in 52 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 2; Plants - 523; Viruses - 0; Other Eukaryotes - 7 (source: NCBI BLink). & (o49873|mloh1_horvu : 134.0) MLO protein homolog 1 - Hordeum vulgare (Barley) & (reliability: 470.0) & (original description: no original description)
Gene families : OG_42_0000124 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000124_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Pseudotsuga release: PSME_00043587-RA | |
Cluster | HCCA clusters: Cluster_3 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
A4A49_23987 | No alias | mlo-like protein 6 | 0.02 | Orthogroups_2024-Update | |
At1g11000 | No alias | MLO-like protein 4 [Source:UniProtKB/Swiss-Prot;Acc:O23693] | 0.03 | Orthogroups_2024-Update | |
At1g61560 | No alias | MLO-like protein 6 [Source:UniProtKB/Swiss-Prot;Acc:Q94KB7] | 0.04 | Orthogroups_2024-Update | |
At3g45290 | No alias | MLO-like protein 3 [Source:UniProtKB/Swiss-Prot;Acc:Q94KB9] | 0.04 | Orthogroups_2024-Update | |
Glyma.04G015500 | No alias | Seven transmembrane MLO family protein | 0.03 | Orthogroups_2024-Update | |
Glyma.06G002000 | No alias | Seven transmembrane MLO family protein | 0.03 | Orthogroups_2024-Update | |
Glyma.12G119300 | No alias | Seven transmembrane MLO family protein | 0.02 | Orthogroups_2024-Update | |
Glyma.12G171300 | No alias | Seven transmembrane MLO family protein | 0.02 | Orthogroups_2024-Update | |
Glyma.20G178800 | No alias | Seven transmembrane MLO family protein | 0.03 | Orthogroups_2024-Update | |
HORVU0Hr1G008830.1 | No alias | Unknown function | 0.03 | Orthogroups_2024-Update | |
LOC_Os03g03700 | No alias | MLO domain containing protein, putative, expressed | 0.02 | Orthogroups_2024-Update | |
LOC_Os05g09050 | No alias | MLO domain containing protein, putative, expressed | 0.02 | Orthogroups_2024-Update | |
LOC_Os10g39520 | No alias | MLO domain containing protein, putative, expressed | 0.02 | Orthogroups_2024-Update | |
PSME_00004047-RA | No alias | (at5g65970 : 302.0) A member of a large family of... | 0.04 | Orthogroups_2024-Update | |
PSME_00004128-RA | No alias | (o49914|mloh1_orysa : 172.0) MLO protein homolog 1... | 0.04 | Orthogroups_2024-Update | |
PSME_00009217-RA | No alias | (p93766|mlo_horvu : 283.0) Protein MLO - Hordeum vulgare... | 0.04 | Orthogroups_2024-Update | |
PSME_00021292-RA | No alias | (at1g61560 : 469.0) A member of a large family of... | 0.04 | Orthogroups_2024-Update | |
PSME_00026865-RA | No alias | (o49914|mloh1_orysa : 126.0) MLO protein homolog 1... | 0.03 | Orthogroups_2024-Update | |
Potri.010G220500 | No alias | Seven transmembrane MLO family protein | 0.02 | Orthogroups_2024-Update | |
Solyc10g044510 | No alias | MLO-like protein (AHRD V3.3 *** K4CZH6_SOLLC) | 0.02 | Orthogroups_2024-Update | |
Solyc11g069220 | No alias | MLO-like protein (AHRD V3.3 *** K4DA78_SOLLC) | 0.02 | Orthogroups_2024-Update |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
BP | GO:0006952 | defense response | IEA | InterProScan predictions |
CC | GO:0016021 | integral component of membrane | IEA | InterProScan predictions |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0003677 | DNA binding | IEP | Predicted GO |
MF | GO:0004568 | chitinase activity | IEP | Predicted GO |
BP | GO:0006022 | aminoglycan metabolic process | IEP | Predicted GO |
BP | GO:0006026 | aminoglycan catabolic process | IEP | Predicted GO |
BP | GO:0006030 | chitin metabolic process | IEP | Predicted GO |
BP | GO:0006032 | chitin catabolic process | IEP | Predicted GO |
BP | GO:0006040 | amino sugar metabolic process | IEP | Predicted GO |
BP | GO:0006355 | regulation of transcription, DNA-templated | IEP | Predicted GO |
BP | GO:0009889 | regulation of biosynthetic process | IEP | Predicted GO |
BP | GO:0010468 | regulation of gene expression | IEP | Predicted GO |
BP | GO:0010556 | regulation of macromolecule biosynthetic process | IEP | Predicted GO |
BP | GO:0016998 | cell wall macromolecule catabolic process | IEP | Predicted GO |
BP | GO:0019219 | regulation of nucleobase-containing compound metabolic process | IEP | Predicted GO |
BP | GO:0019222 | regulation of metabolic process | IEP | Predicted GO |
BP | GO:0031323 | regulation of cellular metabolic process | IEP | Predicted GO |
BP | GO:0031326 | regulation of cellular biosynthetic process | IEP | Predicted GO |
BP | GO:0042737 | drug catabolic process | IEP | Predicted GO |
MF | GO:0043565 | sequence-specific DNA binding | IEP | Predicted GO |
BP | GO:0044036 | cell wall macromolecule metabolic process | IEP | Predicted GO |
BP | GO:0046348 | amino sugar catabolic process | IEP | Predicted GO |
BP | GO:0050789 | regulation of biological process | IEP | Predicted GO |
BP | GO:0050794 | regulation of cellular process | IEP | Predicted GO |
BP | GO:0051171 | regulation of nitrogen compound metabolic process | IEP | Predicted GO |
BP | GO:0051252 | regulation of RNA metabolic process | IEP | Predicted GO |
BP | GO:0060255 | regulation of macromolecule metabolic process | IEP | Predicted GO |
BP | GO:0065007 | biological regulation | IEP | Predicted GO |
BP | GO:0080090 | regulation of primary metabolic process | IEP | Predicted GO |
BP | GO:1901071 | glucosamine-containing compound metabolic process | IEP | Predicted GO |
BP | GO:1901072 | glucosamine-containing compound catabolic process | IEP | Predicted GO |
BP | GO:1901136 | carbohydrate derivative catabolic process | IEP | Predicted GO |
BP | GO:1901565 | organonitrogen compound catabolic process | IEP | Predicted GO |
BP | GO:1903506 | regulation of nucleic acid-templated transcription | IEP | Predicted GO |
BP | GO:2000112 | regulation of cellular macromolecule biosynthetic process | IEP | Predicted GO |
BP | GO:2001141 | regulation of RNA biosynthetic process | IEP | Predicted GO |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR004326 | Mlo | 14 | 217 |
No external refs found! |