PSME_00050855-RA


Description : "(at2g47460 : 188.0) ""MYB12 belongs to subgroup 7 of the R2R3-MYB family. It strongly activates the promoters of chalcone synthase (CHS), flavanone 3-hydroxylase (F3H), flavonol synthase (FLS) and - to a lesser extent - chalcone flavanone isomerase (CHI), but cannot activate the promoters of flavonoid-3'hydroxylase (F3'H) and dihydroflavonol 4-reductase (DF). The activation requires a functional MYB recognition element (MRE). Results from the myb12-1f allele indicate that an activation domain might be present in the C-terminus. Overexpression or knock-out plants do not show any obvious phenotype under greenhouse conditions. Young myb12-ko seedlings contain reduced amounts of flavonoids (quercetin and kaempferol), while seedlings as well as leaves of MYB12-OX plants displayed an increased flavonoid content. They did not show any significant difference in anthocyanin content. Expression of CHS and FLS shows a clear correlation to MYB12 expression levels. CHI and F3H show increased transcript levels in the MYB12-OX lines, but no differences in the knock-out. Even in the absence of functional MYB12, flavonol biosynthesis is not completely absent, suggesting functional redundancy. "" The redundant factors are MYB11 and MYB111 although MYB12 is primarily required for flavonol biosynthesis in roots.; myb domain protein 12 (MYB12); CONTAINS InterPro DOMAIN/s: SANT, DNA-binding (InterPro:IPR001005), Homeodomain-like (InterPro:IPR009057), Myb, DNA-binding (InterPro:IPR014778), HTH transcriptional regulator, Myb-type, DNA-binding (InterPro:IPR017930), Homeodomain-related (InterPro:IPR012287), Myb transcription factor (InterPro:IPR015495); BEST Arabidopsis thaliana protein match is: myb domain protein 11 (TAIR:AT3G62610.1); Has 8833 Blast hits to 8133 proteins in 470 species: Archae - 0; Bacteria - 0; Metazoa - 786; Fungi - 423; Plants - 5965; Viruses - 6; Other Eukaryotes - 1653 (source: NCBI BLink). & (p10290|mybc_maize : 181.0) Anthocyanin regulatory C1 protein - Zea mays (Maize) & (reliability: 376.0) & (original description: no original description)"


Gene families : OG_42_0000002 (Orthogroups_2024-Update) Phylogenetic Tree(s): No tree available for this family

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00050855-RA
Cluster HCCA clusters: Cluster_14

Target Alias Description ECC score Gene Family Method Actions
A4A49_10737 No alias myb-related protein myb4 0.02 Orthogroups_2024-Update
A4A49_20218 No alias transcription factor myb39 0.02 Orthogroups_2024-Update
A4A49_20993 No alias transcription factor myb39 0.02 Orthogroups_2024-Update
A4A49_33530 No alias transcription factor myb26 0.02 Orthogroups_2024-Update
A4A49_38619 No alias transcription factor myb86 0.02 Orthogroups_2024-Update
At2g26960 No alias Myb domain protein 81 [Source:UniProtKB/TrEMBL;Acc:Q9SLH1] 0.02 Orthogroups_2024-Update
At3g12720 No alias AT3g12720/MBK21_8 [Source:UniProtKB/TrEMBL;Acc:Q9LTW2] 0.03 Orthogroups_2024-Update
At3g13540 No alias MYB5 [Source:UniProtKB/TrEMBL;Acc:A0A178VAR4] 0.03 Orthogroups_2024-Update
At5g12870 No alias Transcription factor MYB46... 0.02 Orthogroups_2024-Update
At5g56110 No alias MYB80 [Source:UniProtKB/TrEMBL;Acc:A0A178UM75] 0.02 Orthogroups_2024-Update
Bradi5g16672 No alias myb domain protein 19 0.03 Orthogroups_2024-Update
Brara.B03395.1 No alias MYB class-R2R3 transcription factor 0.03 Orthogroups_2024-Update
Brara.G00616.1 No alias MYB class-R2R3 transcription factor 0.03 Orthogroups_2024-Update
Brara.G03210.1 No alias Unknown function 0.02 Orthogroups_2024-Update
Brara.I01367.1 No alias MYB class-R2R3 transcription factor 0.04 Orthogroups_2024-Update
GRMZM2G028054 No alias myb domain protein 65 0.03 Orthogroups_2024-Update
GRMZM2G057027 No alias myb domain protein 12 0.02 Orthogroups_2024-Update
Glyma.01G196200 No alias myb domain protein 84 0.02 Orthogroups_2024-Update
Glyma.02G110200 No alias myb domain protein 16 0.02 Orthogroups_2024-Update
Glyma.08G059900 No alias MYB-like 102 0.03 Orthogroups_2024-Update
Glyma.11G009400 No alias myb domain protein 107 0.03 Orthogroups_2024-Update
Glyma.11G045400 No alias myb domain protein 84 0.02 Orthogroups_2024-Update
Glyma.13G303200 No alias myb domain protein 14 0.02 Orthogroups_2024-Update
Glyma.17G158000 No alias myb domain protein 84 0.02 Orthogroups_2024-Update
Glyma.18G095600 No alias myb domain protein 101 0.04 Orthogroups_2024-Update
Glyma.19G257400 No alias myb domain protein 4 0.02 Orthogroups_2024-Update
Glyma.20G032900 No alias myb domain protein 106 0.03 Orthogroups_2024-Update
Glyma.20G117000 No alias myb domain protein 62 0.03 Orthogroups_2024-Update
LOC_Os01g36460 No alias MYB family transcription factor, putative, expressed 0.02 Orthogroups_2024-Update
LOC_Os01g74410 No alias MYB family transcription factor, putative, expressed 0.02 Orthogroups_2024-Update
LOC_Os04g50770 No alias MYB family transcription factor, putative, expressed 0.02 Orthogroups_2024-Update
MA_10048467g0010 No alias (at5g35550 : 171.0) TT2 encodes a R2R3 MYB domain... 0.05 Orthogroups_2024-Update
MA_10434028g0010 No alias (at1g68320 : 180.0) putative transcription factor:... 0.04 Orthogroups_2024-Update
MA_14061g0010 No alias (at5g57620 : 229.0) Encodes a putative transcription... 0.03 Orthogroups_2024-Update
MA_175772g0010 No alias (at1g22640 : 206.0) MYB-type transcription factor (MYB3)... 0.03 Orthogroups_2024-Update
MA_20462g0010 No alias (at2g32460 : 219.0) Member of the R2R3 factor gene... 0.04 Orthogroups_2024-Update
MA_53373g0010 No alias (at3g13540 : 224.0) Encodes a member of the MYB family... 0.04 Orthogroups_2024-Update
MA_8626g0010 No alias (at1g22640 : 166.0) MYB-type transcription factor (MYB3)... 0.04 Orthogroups_2024-Update
Mp3g07510.1 No alias transcription factor (MYB) 0.02 Orthogroups_2024-Update
PSME_00014640-RA No alias (at3g27810 : 179.0) Encodes a member of the R2R3-MYB... 0.04 Orthogroups_2024-Update
PSME_00030703-RA No alias (p10290|mybc_maize : 187.0) Anthocyanin regulatory C1... 0.04 Orthogroups_2024-Update
PSME_00031964-RA No alias (at4g13480 : 184.0) Member of the R2R3 factor gene... 0.06 Orthogroups_2024-Update
PSME_00042064-RA No alias (p20026|myb1_horvu : 274.0) Myb-related protein Hv1 -... 0.11 Orthogroups_2024-Update
PSME_00043807-RA No alias (at1g09540 : 265.0) Encodes putative transcription... 0.06 Orthogroups_2024-Update
PSME_00051224-RA No alias (at5g15310 : 212.0) Member of the R2R3 factor gene... 0.04 Orthogroups_2024-Update
PSME_00052652-RA No alias (p20025|myb38_maize : 250.0) Myb-related protein Zm38 -... 0.03 Orthogroups_2024-Update
Potri.019G036400 No alias myb domain protein 5 0.03 Orthogroups_2024-Update
Pp1s46_302V6 No alias MDA7.17; myb family transcription factor [Arabidopsis thaliana] 0.02 Orthogroups_2024-Update
Seita.3G055800.1 No alias MYB class-R2R3 subgroup-13 transcription factor 0.04 Orthogroups_2024-Update
Seita.9G544000.1 No alias MYB class-R2R3 transcription factor 0.02 Orthogroups_2024-Update
Sobic.002G423300.1 No alias MYB class-R2R3 subgroup-19/20 transcription factor 0.03 Orthogroups_2024-Update
Sobic.003G232800.1 No alias Unknown function 0.02 Orthogroups_2024-Update
Sobic.003G274000.1 No alias transcriptional regulator *(MYB26) & MYB class-R2R3... 0.02 Orthogroups_2024-Update
Sobic.004G219800.1 No alias MYB class-R2R3 subgroup-2 transcription factor 0.03 Orthogroups_2024-Update
Sobic.008G020300.1 No alias MYB class-R2R3 subgroup-1 transcription factor 0.03 Orthogroups_2024-Update
Sobic.009G032000.1 No alias MYB class-R2R3 subgroup-19/20 transcription factor 0.02 Orthogroups_2024-Update
Solyc06g005330 No alias R2R3MYB transcription factor 59 0.02 Orthogroups_2024-Update

Type GO Term Name Evidence Source

No GO annotation available for this sequence

Type GO Term Name Evidence Source
CC GO:0000145 exocyst IEP Predicted GO
MF GO:0003885 D-arabinono-1,4-lactone oxidase activity IEP Predicted GO
MF GO:0004857 enzyme inhibitor activity IEP Predicted GO
BP GO:0006887 exocytosis IEP Predicted GO
MF GO:0016614 oxidoreductase activity, acting on CH-OH group of donors IEP Predicted GO
MF GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor IEP Predicted GO
BP GO:0032940 secretion by cell IEP Predicted GO
CC GO:0044448 cell cortex part IEP Predicted GO
BP GO:0046903 secretion IEP Predicted GO
MF GO:0050660 flavin adenine dinucleotide binding IEP Predicted GO
MF GO:0050662 coenzyme binding IEP Predicted GO
CC GO:0099023 tethering complex IEP Predicted GO
InterPro domains Description Start Stop
IPR001005 SANT/Myb 29 76
IPR001005 SANT/Myb 82 127
No external refs found!