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- Pseudotsuga menziesii
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- PSME_00055410-RA
PSME_00055410-RA
Description : (at2g30950 : 502.0) Metalloprotease that functions in thylakoid membrane biogenesis. Involved in the repair of PSII following damaged incurred during photoinhibition. Forms a complex with VAR1. Mutants show a variegated phenotype, which decreases during development. Transcript and protein levels increase with light intensity.; VARIEGATED 2 (VAR2); FUNCTIONS IN: metallopeptidase activity, ATP-dependent peptidase activity, ATPase activity, zinc ion binding; INVOLVED IN: photoinhibition, oxygen and reactive oxygen species metabolic process, thylakoid membrane organization, PSII associated light-harvesting complex II catabolic process, protein catabolic process; LOCATED IN: in 6 components; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Peptidase M41, FtsH (InterPro:IPR005936), ATPase, AAA+ type, core (InterPro:IPR003593), ATPase, AAA-type, core (InterPro:IPR003959), ATPase, AAA-type, conserved site (InterPro:IPR003960), Peptidase M41 (InterPro:IPR000642), Peptidase M41, FtsH extracellular (InterPro:IPR011546); BEST Arabidopsis thaliana protein match is: FTSH protease 8 (TAIR:AT1G06430.1); Has 42824 Blast hits to 40381 proteins in 3333 species: Archae - 1597; Bacteria - 18199; Metazoa - 4991; Fungi - 3835; Plants - 3350; Viruses - 34; Other Eukaryotes - 10818 (source: NCBI BLink). & (o82150|ftsh_tobac : 329.0) Cell division protease ftsH homolog, chloroplast precursor (EC 3.4.24.-) (DS9) - Nicotiana tabacum (Common tobacco) & (reliability: 1004.0) & (original description: no original description)
Expression Profile
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Co-expression Networks
| Type | Description | Actions |
| Neighborhood | Pseudotsuga release: PSME_00055410-RA | |
| Cluster | HCCA clusters: Cluster_110 | |
Expression Context Conservation (ECC)
| Target | Alias | Description | ECC score | Gene Family Method | Actions |
| Brara.H02960.1 | No alias | protease *(FtsH2/8) & EXECUTER-cleavage protease... | 0.02 | Orthogroups_2024-Update | |
| GRMZM2G126361 | No alias | FtsH extracellular protease family | 0.02 | Orthogroups_2024-Update | |
| Solyc02g081550 | No alias | LeftsH6FtsH protease | 0.02 | Orthogroups_2024-Update | |
| Sopen07g026900 | No alias | Peptidase family M41 | 0.02 | Orthogroups_2024-Update | |
Functional Annotation
| Type | GO Term | Name | Evidence | Source |
| MF | GO:0000166 | nucleotide binding | None | Extended |
| MF | GO:0003674 | molecular_function | None | Extended |
| MF | GO:0005488 | binding | None | Extended |
| MF | GO:0005524 | ATP binding | IEA | InterProScan predictions |
| MF | GO:0008144 | drug binding | None | Extended |
| MF | GO:0017076 | purine nucleotide binding | None | Extended |
| MF | GO:0030554 | adenyl nucleotide binding | None | Extended |
| MF | GO:0032553 | ribonucleotide binding | None | Extended |
| MF | GO:0032555 | purine ribonucleotide binding | None | Extended |
| MF | GO:0032559 | adenyl ribonucleotide binding | None | Extended |
| MF | GO:0035639 | purine ribonucleoside triphosphate binding | None | Extended |
| MF | GO:0036094 | small molecule binding | None | Extended |
| MF | GO:0043167 | ion binding | None | Extended |
| MF | GO:0043168 | anion binding | None | Extended |
| MF | GO:0097159 | organic cyclic compound binding | None | Extended |
| MF | GO:0097367 | carbohydrate derivative binding | None | Extended |
| MF | GO:1901265 | nucleoside phosphate binding | None | Extended |
| MF | GO:1901363 | heterocyclic compound binding | None | Extended |
| Type | GO Term | Name | Evidence | Source |
| MF | GO:0004222 | metalloendopeptidase activity | IEP | Predicted GO |
| MF | GO:0004427 | inorganic diphosphatase activity | IEP | Predicted GO |
| MF | GO:0004611 | phosphoenolpyruvate carboxykinase activity | IEP | Predicted GO |
| MF | GO:0004612 | phosphoenolpyruvate carboxykinase (ATP) activity | IEP | Predicted GO |
| MF | GO:0005215 | transporter activity | IEP | Predicted GO |
| BP | GO:0006006 | glucose metabolic process | IEP | Predicted GO |
| BP | GO:0006094 | gluconeogenesis | IEP | Predicted GO |
| MF | GO:0008237 | metallopeptidase activity | IEP | Predicted GO |
| MF | GO:0009678 | hydrogen-translocating pyrophosphatase activity | IEP | Predicted GO |
| MF | GO:0015098 | molybdate ion transmembrane transporter activity | IEP | Predicted GO |
| MF | GO:0015103 | inorganic anion transmembrane transporter activity | IEP | Predicted GO |
| MF | GO:0015399 | primary active transmembrane transporter activity | IEP | Predicted GO |
| MF | GO:0015405 | P-P-bond-hydrolysis-driven transmembrane transporter activity | IEP | Predicted GO |
| BP | GO:0015689 | molybdate ion transport | IEP | Predicted GO |
| BP | GO:0015698 | inorganic anion transport | IEP | Predicted GO |
| BP | GO:0019319 | hexose biosynthetic process | IEP | Predicted GO |
| MF | GO:0022804 | active transmembrane transporter activity | IEP | Predicted GO |
| MF | GO:0022857 | transmembrane transporter activity | IEP | Predicted GO |
| BP | GO:0046364 | monosaccharide biosynthetic process | IEP | Predicted GO |
| MF | GO:0061630 | ubiquitin protein ligase activity | IEP | Predicted GO |
| MF | GO:0061659 | ubiquitin-like protein ligase activity | IEP | Predicted GO |
| InterPro domains | Description | Start | Stop |
| IPR003959 | ATPase_AAA_core | 271 | 402 |
