A4A49_12016

Description : dna topoisomerase 2

Gene families : OG_42_0003889 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0003889_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Nicotiana release: A4A49_12016
Cluster	HCCA clusters: Cluster_104

Target	Alias	Description	ECC score	Gene Family Method
98330	No alias	topoisomerase II	0.03	Orthogroups_2024-Update
At3g23890	No alias	DNA topoisomerase 2 [Source:UniProtKB/Swiss-Prot;Acc:P30182]	0.04	Orthogroups_2024-Update
Brara.A00830.1	No alias	DNA topoisomerase *(TOP2)	0.05	Orthogroups_2024-Update
Cre01.g009250	No alias	topoisomerase II	0.01	Orthogroups_2024-Update
Glyma.10G090000	No alias	topoisomerase II	0.06	Orthogroups_2024-Update
Glyma.15G276000	No alias	topoisomerase II	0.04	Orthogroups_2024-Update
Kfl00053_0310	kfl00053_0310_v1.1	(o24308\|top2_pea : 1259.0) DNA topoisomerase 2 (EC...	0.02	Orthogroups_2024-Update
MA_133272g0010	No alias	(at3g23890 : 1518.0) Encodes a topoisomerase II that is...	0.05	Orthogroups_2024-Update
MA_6634g0010	No alias	(o24308\|top2_pea : 1595.0) DNA topoisomerase 2 (EC...	0.07	Orthogroups_2024-Update
Mp3g13420.1	No alias	DNA topoisomerase (TOP2)	0.02	Orthogroups_2024-Update
Pp1s33_203V6	No alias	dna topoisomerase ii	0.03	Orthogroups_2024-Update
Solyc01g087500	No alias	DNA topoisomerase 2 (AHRD V3.3 *** K4AYE0_SOLLC)	0.06	Orthogroups_2024-Update
Sopen01g034420	No alias	DNA gyrase/topoisomerase IV, subunit A	0.03	Orthogroups_2024-Update
evm.model.contig_3477.2	No alias	(at3g23890 : 1176.0) Encodes a topoisomerase II that is...	0.04	Orthogroups_2024-Update
evm.model.tig00021432.55	No alias	(o24308\|top2_pea : 775.0) DNA topoisomerase 2 (EC...	0.03	Orthogroups_2024-Update
evm.model.tig00021433.1	No alias	(at3g23890 : 211.0) Encodes a topoisomerase II that is...	0.04	Orthogroups_2024-Update
evm.model.tig00021433.2	No alias	(at3g23890 : 475.0) Encodes a topoisomerase II that is...	0.02	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	IEA	InterProScan predictions
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003916	DNA topoisomerase activity	None	Extended
MF	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity	IEA	InterProScan predictions
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	InterProScan predictions
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006265	DNA topological change	IEA	InterProScan predictions
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006996	organelle organization	None	Extended
MF	GO:0008094	DNA-dependent ATPase activity	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016043	cellular component organization	None	Extended
MF	GO:0016462	pyrophosphatase activity	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	None	Extended
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	None	Extended
MF	GO:0016853	isomerase activity	None	Extended
MF	GO:0016887	ATPase activity	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0017111	nucleoside-triphosphatase activity	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0042623	ATPase activity, coupled	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0051276	chromosome organization	None	Extended
MF	GO:0061505	DNA topoisomerase II activity	None	Extended
BP	GO:0071103	DNA conformation change	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0071840	cellular component organization or biogenesis	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:0140097	catalytic activity, acting on DNA	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR002205	Topo_IIA_A/C	692	1148
IPR003594	HATPase_C	70	216
IPR006171	TOPRIM_domain	448	546
IPR031660	TOPRIM_C	562	689
IPR013506	Topo_IIA_bsu_dom2	277	418

External Links

No external refs found!

A4A49_12016

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation