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Cluster_146 vs cluster_0126 graph comparison</span><span class="icon-bar"></span><span class="icon-bar"></span></button><a class="navbar-brand hidden-xs" href="/"><img src="/static/img/icon-48x48.png" style="max-width:100px;margin-left:-7px;margin-top: -13px;float:left;margin-right:5px;" width="48px"></a><a class="navbar-brand visible-xs" href="/"><img src="/static/img/icon-32x32.png" style="max-width:100px; margin-top: -7px;" width="32px"></a></div><div id="navbar" class="navbar-collapse collapse"><ul class="nav navbar-nav navbar-left"><li><a href="/species/"> Species</a></li><li><a href="#" class="dropdown-toggle" data-toggle="dropdown" role="button" aria-haspopup="true" aria-expanded="false">Tools<span class="caret"></span></a><ul class="dropdown-menu"><li class="dropdown-header"> Expression Profiles</li><li><a href="/profile_comparison/">Compare profiles</a></li><li><a href="/heatmap/">Create heatmap</a></li><li><a href="/profile/export/species">Export expression levels</a></li><li class="divider"></li><li class="dropdown-header">Expression Specificity</li><li><a href="/specificity_comparison/">Compare specificities</a></li><li><a href="/search/specific/profiles">Find specific profiles</a></li><li class="divider"></li><li class="dropdown-header">Co-expression Networks</li><li><a href="/custom_network/">Create custom network</a></li><li><a href="/search/enriched/clusters">Find enriched clusters</a></li></ul></li><li><a href="#" class="dropdown-toggle" data-toggle="dropdown" role="button" aria-haspopup="true" aria-expanded="false">Search<span class="caret"></span></a><ul class="dropdown-menu"><li><a href="/search/advanced"> Search<span class="text-muted"> (advanced)</span></a></li><li class="divider"></li><li><a href="/blast/">BLAST</a></li></ul></li></ul><ul class="nav navbar-nav navbar-right"><li><form class="navbar-form" role="search" method="post" id="search-form" name="search-form" action="/search/"><input id="csrf_token" name="csrf_token" type="hidden" value="IjIxOTdkMzY4ZTI3ODQ5NmUzMjEwZjRhODRjYTVhZDNlYzVmY2RmYWIi.GmU4DQ.0_V2JscB_LMn4PESWkIUNb1L8i0"><div class="form-group input-group"><input class="form-control" id="terms" name="terms" placeholder="Search" required type="text" value><div class="input-group-btn"><button type="submit" class="btn btn-primary" value="Search" data-toggle="modal" data-target="#loaderModal"><i class="fa fa-search"></i></button></div></div></form></li><li><a href="#" class="dropdown-toggle" data-toggle="dropdown" role="button" aria-haspopup="true" aria-expanded="false">Help<span class="caret"></span></a><ul class="dropdown-menu"><li><a href="https://github.com/sepro/CoNekT/blob/master/docs/tutorials/overview.md"> Tutorial<span class="text-muted"></span></a></li><li><a href="/contact"> Contact</a></li></li></ul></li><li class="dropdown"></li></ul></div></div></div><div class="container"></div><div class="container"><div class="top-pad"><div class="sidebar-sequence" id="sidebar"><p>Jump to ...</p><nav id="navbar-side"><ul class="nav nav-pills nav-stacked" data-spy="affix"><li><a href="#expression_profile">Profile</a></li><li><a href="#coexpression_networks">Networks</a></li><li><a href="#expression_conservation">ECC</a></li><li><a href="#annotation">Annotation</a></li><li><a href="#links">Links</a></li></ul></nav></div><ol class="breadcrumb"><li><a href="/">Home</a></li><li><a href="/species/">Species</a></li><li><a href="/species/view/25"><em>Sorghum bicolor</em></a></li><li> Sequence</li><li class="active"><strong>Sobic.005G116900.1</strong></li></ol><h1><strong>Sobic.005G116900.1</strong></h1><br><p><strong>Description :</strong> Unknown function</p><br><div><p><strong><abbr title="Click to show help" href="/help/gene_family" data-target="#helpModal">Gene families</abbr> :</strong><a href="/family/view/962411"> OG_42_0002602</a> (Orthogroups_2024-Update) Phylogenetic Tree(s):<a href="/tree/view/156299"> OG0002602_tree</a></p><p><strong>Sequence :</strong><a href="/sequence/modal/coding/951161" data-target="#profileModal">coding</a> (<a href="/sequence/fasta/coding/951161">download</a>),<a href="/sequence/modal/protein/951161" data-target="#profileModal"> protein</a> (<a href="/sequence/fasta/protein/951161">download</a>)</p></div><h3 class="banner-blue" id="expression_profile"> Expression Profile</h3><div class="pull-right"><a href="#" class="btn btn-default" id="enable_pan" data-toggle="tooltip" title="Toggle Pan"><i class="fa fa-arrows" aria-hidden="true"></i></a><a href="#" class="btn btn-default" id="enable_zoom" data-toggle="tooltip" title="Toggle zoom"><i class="fa fa-search" aria-hidden="true"></i></a></div><div style="height:550px; max-height:550px; margin-top:30px"><canvas id="expression-profile" class="center-block" height="550"/></div><br><div class="pull-right"><a href="/profile/download/plot/640981" class="btn btn-primary" download="plot_640981.txt">Download</a></div><p><strong>Note:</strong>Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available<a href="/profile/view/640981"> here</a>.</p><br><div><h3 class="banner-blue" id="coexpression_networks">Co-expression Networks</h3><div class="table-responsive"><table class="table table-striped table-separated" id="coexpression_table"><thead><tr><th data-sort="string-ins"><span class="sort-icon"></span>Type</th><th data-sort="string-ins"><span class="sort-icon"></span>Description</th><th>Actions</th></tr></thead><tbody><tr><td><abbr title="Click to show help" href="/help/neighborhood" data-target="#helpModal">Neighborhood</abbr></td><td>Sorghum bicolor:<strong> Sobic.005G116900.1</strong></td><td><a href="/network/download/neighbors/512658" data-toggle="tooltip" data-placement="top" title="Download direct neighbors" download="neighbors_512658.txt"><i class="fa fa-list"></i></span><a href="/network/graph/512658" data-toggle="tooltip" data-placement="top" title="View neighborhood as graph"><i class="fa fa-sitemap"></i></a><span class="text-muted" data-toggle="tooltip" data-placement="top" title="Disabled for neighborhoods"><i class="fa fa-area-chart"></i></span><span class="text-muted" data-toggle="tooltip" data-placement="top" title="Disabled for neighborhoods"><i class="fa fa-table"></i></span></td></tr><tr><td><abbr title="Click to show help" href="/help/cluster" data-target="#helpModal">Cluster</abbr></td><td>HCAA Clusters:<strong><a href="/cluster/view/8091" class="qtip_tooltip" qtip_href="/cluster/tooltip/8091"> Cluster_156</a></strong></td><td><a href="/cluster/view/8091" data-toggle="tooltip" data-placement="top" title="View cluster as table"><i class="fa fa-list"></i></a><a href="/cluster/graph/8091" data-toggle="tooltip" data-placement="top" title="View cluster as graph"><i class="fa fa-sitemap"></i></a><a href="/profile_comparison/cluster/8091" data-toggle="tooltip" data-placement="top" title="Compare profiles in this cluster"><i class="fa fa-area-chart"></i></a><a href="/heatmap/cluster/8091" data-toggle="tooltip" data-placement="top" title="Heatmap of profiles in this cluster"><i class="fa fa-table"></i></a></td></tr></tbody></table></div></div><br><h3 class="banner-blue" id="expression_conservation">Expression Context Conservation (<abbr title="Click to show help" href="/help/ecc" data-target="#helpModal">ECC</abbr>)</h3><div class="table-responsive"><table class="table table-striped table-separated" id="ecc_hits_table"><thead><tr><th data-sort="string-ins"><span class="sort-icon"></span>Target</th><th data-sort="string-ins"><span class="sort-icon"></span>Alias</th><th data-sort="string-ins"><span class="sort-icon"></span>Description</th><th data-sort="float"><span class="sort-icon"></span><abbr title="Click to show help" href="/help/ecc" data-target="#helpModal">ECC</abbr> score</th><th data-sort="string-ins"><span class="sort-icon"></span>Gene Family Method</th><th>Actions</th></tr></thead><tbody><tr><td><a href="/sequence/view/886204" class="qtip_tooltip qtip_dynamic_tooltip" qtip_href="/sequence/tooltip/886204">Brara.I05142.1</a></td><td><span class="text-muted">No alias</span></td><td>Unknown function</td><td>0.04</td><td>Orthogroups_2024-Update</td><td><a href="/ecc/graph_pair/3686335" data-toggle="tooltip" data-placement="top" title="View ECC pair as graph"><i class="fa fa-eye"></i></a><a href="/ecc/graph/951161/21/42" data-toggle="tooltip" data-placement="top" title="View ECC as graph"><i class="fa fa-sitemap"></i></a></td></tr><tr><td><a href="/sequence/view/213208" class="qtip_tooltip qtip_dynamic_tooltip" qtip_href="/sequence/tooltip/213208">LOC_Os04g57360</a></td><td><span class="text-muted">No alias</span></td><td>expressed protein</td><td>0.02</td><td>Orthogroups_2024-Update</td><td><a href="/ecc/graph_pair/3686351" data-toggle="tooltip" data-placement="top" title="View ECC pair as graph"><i class="fa fa-eye"></i></a><a href="/ecc/graph/951161/21/42" data-toggle="tooltip" data-placement="top" title="View ECC as graph"><i class="fa fa-sitemap"></i></a></td></tr></tbody></table></div><br><h3 class="banner-blue" id="annotation">Functional Annotation</h3><div class="panel with-nav-tabs panel-default"><div class="panel-heading"><ul class="nav nav-tabs"><li class="active"><a href="#tab1default" data-toggle="tab">GO</a></li><li><a href="#tab2default" data-toggle="tab">Predicted GO</a></li><li><a href="#tab3default" data-toggle="tab">InterPro</a></li></ul></div><div><div class="tab-content"><div class="tab-pane fade in active" id="tab1default"><div class="table-responsive"><table class="table table-striped table-fixed" id="go_table"><thead><tr><th class="col-xs-1" data-sort="string-ins"><span class="sort-icon"></span>Type</th><th class="col-xs-2" data-sort="string-ins"><span class="sort-icon"></span><abbr title="Click to show help" href="/help/go" data-target="#helpModal">GO</abbr> Term</th><th class="col-xs-6" data-sort="string-ins"><span class="sort-icon"></span>Name</th><th class="col-xs-1" data-sort="string-ins"><span class="sort-icon"></span>Evidence</th><th class="col-xs-2" data-sort="string-ins"><span class="sort-icon"></span>Source</th></tr></thead><tbody><tr><td class="col-xs-12"><p>No GO annotation available for this sequence</p></td></tr></tbody></table></div><div class="panel-body"><a href="#" id="go_toggle">Toggle parental</a></div></div><div class="tab-pane fade" id="tab2default"><div class="table-responsive"><table class="table table-striped table-fixed" id="predicted_go_table"><thead><tr><th class="col-xs-1" data-sort="string-ins"><span class="sort-icon"></span>Type</th><th class="col-xs-2" data-sort="string-ins"><span class="sort-icon"></span><abbr title="Click to show help" href="/help/go" data-target="#helpModal">GO</abbr> Term</th><th class="col-xs-6" data-sort="string-ins"><span class="sort-icon"></span>Name</th><th class="col-xs-1" data-sort="string-ins"><span class="sort-icon"></span>Evidence</th><th class="col-xs-2" data-sort="string-ins"><span class="sort-icon"></span>Source</th></tr></thead><tbody><tr style="clear:both;"><td class="col-xs-1">CC</td><td class="col-xs-2"><a href="/go/view/124" data-toggle="tooltip" data-placement="top" title=""A protein complex that includes a ubiquitin-protein ligase and enables ubiquitin protein ligase activity. The complex also contains other proteins that may confer substrate specificity on the complex." [GOC:jh2, PMID:9529603]">GO:0000151</a></td><td class="col-xs-6">ubiquitin ligase complex</td><td class="col-xs-1">IEP</td><td class="col-xs-2">Predicted GO</td></tr><tr style="clear:both;"><td class="col-xs-1">CC</td><td class="col-xs-2"><a href="/go/view/125" data-toggle="tooltip" data-placement="top" title=""A ubiquitin ligase complex found in the nucleus." [GOC:mah]">GO:0000152</a></td><td class="col-xs-6">nuclear ubiquitin ligase complex</td><td class="col-xs-1">IEP</td><td class="col-xs-2">Predicted GO</td></tr><tr style="clear:both;"><td class="col-xs-1">MF</td><td class="col-xs-2"><a href="/go/view/3744" data-toggle="tooltip" data-placement="top" title=""Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages." [GOC:BioGRID, GOC:jh2, PMID:9635407]">GO:0004842</a></td><td class="col-xs-6">ubiquitin-protein transferase activity</td><td class="col-xs-1">IEP</td><td class="col-xs-2">Predicted GO</td></tr><tr style="clear:both;"><td class="col-xs-1">CC</td><td class="col-xs-2"><a href="/go/view/4289" data-toggle="tooltip" data-placement="top" title=""A location, relative to cellular compartments and structures, occupied by a macromolecular machine when it carries out a molecular function. There are two ways in which the gene ontology describes locations of gene products: (1) relative to cellular structures (e.g., cytoplasmic side of plasma membrane) or compartments (e.g., mitochondrion), and (2) the stable macromolecular complexes of which they are parts (e.g., the ribosome)." [GOC:pdt, NIF_Subcellular:sao-1337158144]">GO:0005575</a></td><td class="col-xs-6">cellular_component</td><td class="col-xs-1">IEP</td><td class="col-xs-2">Predicted GO</td></tr><tr style="clear:both;"><td class="col-xs-1">CC</td><td class="col-xs-2"><a href="/go/view/4383" data-toggle="tooltip" data-placement="top" title=""A ubiquitin ligase complex that degrades mitotic cyclins and anaphase inhibitory protein, thereby triggering sister chromatid separation and exit from mitosis. Substrate recognition by APC occurs through degradation signals, the most common of which is termed the Dbox degradation motif, originally discovered in cyclin B." [GOC:jh, GOC:vw, PMID:10465783, PMID:10611969]">GO:0005680</a></td><td class="col-xs-6">anaphase-promoting complex</td><td class="col-xs-1">IEP</td><td class="col-xs-2">Predicted GO</td></tr><tr style="clear:both;"><td class="col-xs-1">BP</td><td class="col-xs-2"><a href="/go/view/5132" data-toggle="tooltip" data-placement="top" title=""The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein." [GOC:go_curators]">GO:0006511</a></td><td class="col-xs-6">ubiquitin-dependent protein catabolic process</td><td class="col-xs-1">IEP</td><td class="col-xs-2">Predicted GO</td></tr><tr style="clear:both;"><td class="col-xs-1">BP</td><td class="col-xs-2"><a href="/go/view/8463" data-toggle="tooltip" data-placement="top" title=""The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome." [GOC:tb]">GO:0010498</a></td><td class="col-xs-6">proteasomal protein catabolic process</td><td class="col-xs-1">IEP</td><td class="col-xs-2">Predicted GO</td></tr><tr style="clear:both;"><td class="col-xs-1">MF</td><td class="col-xs-2"><a href="/go/view/9201" data-toggle="tooltip" data-placement="top" title=""Catalysis of the reaction: UDP-glucuronate + 3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein = UDP + 3-beta-D-glucuronosyl-3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein." [EC:2.4.1.135]">GO:0015018</a></td><td class="col-xs-6">galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity</td><td class="col-xs-1">IEP</td><td class="col-xs-2">Predicted GO</td></tr><tr style="clear:both;"><td class="col-xs-1">MF</td><td class="col-xs-2"><a href="/go/view/9203" data-toggle="tooltip" data-placement="top" title=""Catalysis of the reaction: UDP-glucuronate + acceptor = UDP + acceptor beta-D-glucuronoside." [EC:2.4.1.17]">GO:0015020</a></td><td class="col-xs-6">glucuronosyltransferase activity</td><td class="col-xs-1">IEP</td><td class="col-xs-2">Predicted GO</td></tr><tr style="clear:both;"><td class="col-xs-1">CC</td><td class="col-xs-2"><a href="/go/view/10075" data-toggle="tooltip" data-placement="top" title=""A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it." [GOC:dos, GOC:mah, ISBN:0815316194]">GO:0016020</a></td><td class="col-xs-6">membrane</td><td class="col-xs-1">IEP</td><td class="col-xs-2">Predicted GO</td></tr><tr style="clear:both;"><td class="col-xs-1">MF</td><td class="col-xs-2"><a href="/go/view/10377" data-toggle="tooltip" data-placement="top" title=""Catalysis of the transfer of a palmitoyl (CH3-[CH2]14-CO-) group to an acceptor molecule." [GOC:ai]">GO:0016409</a></td><td class="col-xs-6">palmitoyltransferase activity</td><td class="col-xs-1">IEP</td><td class="col-xs-2">Predicted GO</td></tr><tr style="clear:both;"><td class="col-xs-1">MF</td><td class="col-xs-2"><a href="/go/view/10669" data-toggle="tooltip" data-placement="top" title=""Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2." [ISBN:0198506732]">GO:0016740</a></td><td class="col-xs-6">transferase activity</td><td class="col-xs-1">IEP</td><td class="col-xs-2">Predicted GO</td></tr><tr style="clear:both;"><td class="col-xs-1">MF</td><td class="col-xs-2"><a href="/go/view/12704" data-toggle="tooltip" data-placement="top" title=""Catalysis of the transfer of a ubiquitin-like from one protein to another via the reaction X-ULP + Y --> Y-ULP + X, where both X-ULP and Y-ULP are covalent linkages. ULP represents a ubiquitin-like protein." [GOC:mah, GOC:rn, PMID:10806345, PMID:10884686]">GO:0019787</a></td><td class="col-xs-6">ubiquitin-like protein transferase activity</td><td class="col-xs-1">IEP</td><td class="col-xs-2">Predicted GO</td></tr><tr style="clear:both;"><td class="col-xs-1">BP</td><td class="col-xs-2"><a href="/go/view/12846" data-toggle="tooltip" data-placement="top" title=""The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent modification of the target protein." [GOC:go_curators]">GO:0019941</a></td><td class="col-xs-6">modification-dependent protein catabolic process</td><td class="col-xs-1">IEP</td><td class="col-xs-2">Predicted GO</td></tr><tr style="clear:both;"><td class="col-xs-1">BP</td><td class="col-xs-2"><a href="/go/view/13620" data-toggle="tooltip" data-placement="top" title=""The directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai]">GO:0030001</a></td><td class="col-xs-6">metal ion transport</td><td class="col-xs-1">IEP</td><td class="col-xs-2">Predicted GO</td></tr><tr style="clear:both;"><td class="col-xs-1">BP</td><td class="col-xs-2"><a href="/go/view/13768" data-toggle="tooltip" data-placement="top" title=""The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds." [GOC:mah]">GO:0030163</a></td><td class="col-xs-6">protein catabolic process</td><td class="col-xs-1">IEP</td><td class="col-xs-2">Predicted GO</td></tr><tr style="clear:both;"><td class="col-xs-1">BP</td><td class="col-xs-2"><a href="/go/view/14682" data-toggle="tooltip" data-placement="top" title=""The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by the anaphase-promoting complex, and mediated by the proteasome." [GOC:mah, PMID:15380083, PMID:15840442]">GO:0031145</a></td><td class="col-xs-6">anaphase-promoting complex-dependent catabolic process</td><td class="col-xs-1">IEP</td><td class="col-xs-2">Predicted GO</td></tr><tr style="clear:both;"><td class="col-xs-1">CC</td><td class="col-xs-2"><a href="/go/view/14969" data-toggle="tooltip" data-placement="top" title=""Any ubiquitin ligase complex in which the catalytic core consists of a member of the cullin family and a RING domain protein; the core is associated with one or more additional proteins that confer substrate specificity." [PMID:15571813, PMID:15688063]">GO:0031461</a></td><td class="col-xs-6">cullin-RING ubiquitin ligase complex</td><td class="col-xs-1">IEP</td><td class="col-xs-2">Predicted GO</td></tr><tr style="clear:both;"><td class="col-xs-1">BP</td><td class="col-xs-2"><a href="/go/view/21404" data-toggle="tooltip" data-placement="top" title=""The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome." [GOC:go_curators]">GO:0043161</a></td><td class="col-xs-6">proteasome-mediated ubiquitin-dependent protein catabolic process</td><td class="col-xs-1">IEP</td><td class="col-xs-2">Predicted GO</td></tr><tr style="clear:both;"><td class="col-xs-1">BP</td><td class="col-xs-2"><a href="/go/view/21832" data-toggle="tooltip" data-placement="top" title=""The chemical reactions and pathways resulting in the breakdown of a macromolecule, initiated by covalent modification of the target molecule." [GOC:jl]">GO:0043632</a></td><td class="col-xs-6">modification-dependent macromolecule catabolic process</td><td class="col-xs-1">IEP</td><td class="col-xs-2">Predicted GO</td></tr><tr style="clear:both;"><td class="col-xs-1">BP</td><td class="col-xs-2"><a href="/go/view/22433" data-toggle="tooltip" data-placement="top" title=""The chemical reactions and pathways resulting in the breakdown of a macromolecule, any large molecule including proteins, nucleic acids and carbohydrates, as carried out by individual cells." [CHEBI:33694, GOC:jl]">GO:0044265</a></td><td class="col-xs-6">cellular macromolecule catabolic process</td><td class="col-xs-1">IEP</td><td class="col-xs-2">Predicted GO</td></tr><tr style="clear:both;"><td class="col-xs-1">MF</td><td class="col-xs-2"><a href="/go/view/24787" data-toggle="tooltip" data-placement="top" title=""Enables the transfer of metal ions from one side of a membrane to the other." [GOC:ai]">GO:0046873</a></td><td class="col-xs-6">metal ion transmembrane transporter activity</td><td class="col-xs-1">IEP</td><td class="col-xs-2">Predicted GO</td></tr><tr style="clear:both;"><td class="col-xs-1">BP</td><td class="col-xs-2"><a href="/go/view/28281" data-toggle="tooltip" data-placement="top" title=""The hydrolysis of a peptide bond or bonds within a protein as part of the chemical reactions and pathways resulting in the breakdown of a protein by individual cells." [GOC:ai, GOC:dph, GOC:tb]">GO:0051603</a></td><td class="col-xs-6">proteolysis involved in cellular protein catabolic process</td><td class="col-xs-1">IEP</td><td class="col-xs-2">Predicted GO</td></tr><tr style="clear:both;"><td class="col-xs-1">MF</td><td class="col-xs-2"><a href="/go/view/31315" data-toggle="tooltip" data-placement="top" title=""Catalysis of the transfer of ubiquitin to a substrate protein via the reaction X-ubiquitin + S -> X + S-ubiquitin, where X is either an E2 or E3 enzyme, the X-ubiquitin linkage is a thioester bond, and the S-ubiquitin linkage is an amide bond: an isopeptide bond between the C-terminal glycine of ubiquitin and the epsilon-amino group of lysine residues in the substrate or, in the linear extension of ubiquitin chains, a peptide bond the between the C-terminal glycine and N-terminal methionine of ubiquitin residues." [GOC:BioGRID, GOC:dph, GOC:mah, GOC:tb, PMID:22863777]">GO:0061630</a></td><td class="col-xs-6">ubiquitin protein ligase activity</td><td class="col-xs-1">IEP</td><td class="col-xs-2">Predicted GO</td></tr><tr style="clear:both;"><td class="col-xs-1">MF</td><td class="col-xs-2"><a href="/go/view/31342" data-toggle="tooltip" data-placement="top" title=""Catalysis of the transfer of a ubiquitin-like protein (ULP) to a substrate protein via the reaction X-ULP + S --> X + S-ULP, where X is either an E2 or E3 enzyme, the X-ULP linkage is a thioester bond, and the S-ULP linkage is an isopeptide bond between the C-terminal glycine of ULP and the epsilon-amino group of lysine residues in the substrate." [GOC:dph]">GO:0061659</a></td><td class="col-xs-6">ubiquitin-like protein ligase activity</td><td class="col-xs-1">IEP</td><td class="col-xs-2">Predicted GO</td></tr><tr style="clear:both;"><td class="col-xs-1">MF</td><td class="col-xs-2"><a href="/go/view/36450" data-toggle="tooltip" data-placement="top" title=""Interacting selectively and non-covalently with any member of the cullin family, hydrophobic proteins that act as scaffolds for ubiquitin ligases (E3)." [GOC:ha, InterPro:IPR016158, PMID:18698375]">GO:0097602</a></td><td class="col-xs-6">cullin family protein binding</td><td class="col-xs-1">IEP</td><td class="col-xs-2">Predicted GO</td></tr><tr style="clear:both;"><td class="col-xs-1">BP</td><td class="col-xs-2"><a href="/go/view/40819" data-toggle="tooltip" data-placement="top" title=""The chemical reactions and pathways resulting in the breakdown of organonitrogen compound." [GOC:pr, GOC:TermGenie]">GO:1901565</a></td><td class="col-xs-6">organonitrogen compound catabolic process</td><td class="col-xs-1">IEP</td><td class="col-xs-2">Predicted GO</td></tr><tr style="clear:both;"><td class="col-xs-1">CC</td><td class="col-xs-2"><a href="/go/view/45310" data-toggle="tooltip" data-placement="top" title=""A protein complex capable of catalyzing the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor)." [GOC:bhm, PMID:16540464]">GO:1990234</a></td><td class="col-xs-6">transferase complex</td><td class="col-xs-1">IEP</td><td class="col-xs-2">Predicted GO</td></tr></tbody></table></div></div><div class="tab-pane fade" id="tab3default"><div class="panel-body"><p>No InterPro domains available for this sequence</p></div></div></div></div></div><div class="row"><div class="col-lg-12 col-md-12 col-sm-12"><div class="panel panel-default"><div class="panel-heading" id="links">External Links</div><div class="table-responsive"><table class="table table-striped table-separated"><tbody><tr><td><em>No external refs found!</em></td></td></tr></tbody></table></div></div></div></div><div class="modal" id="profileModal" tabindex="-1" role="dialog" aria-labelledby="profileModalLabel"><div class="modal-dialog" role="document" style="width:1000px;height:800px;"><div class="modal-content"></div></div></div></div></div></div><footer class="footer" id="footer"><div class="container"><div class="row"><div class="col-xs-2"><strong class="text-muted"><a href="/features" class="text-muted">CoNekT</a></strong></div><div class="col-xs-2"><a href="/about" class="text-muted">About</a></div><div class="col-xs-2"><a href="/contact" class="text-muted">Contact</a></div><div class="col-xs-2"><a href="/disclaimer" class="text-muted">Disclaimer</a></div><div class="col-xs-2"><a href="/privacy" class="text-muted">Privacy policy</a></div></div></div></footer><div class="modal" id="helpModal" tabindex="-1" role="dialog" aria-labelledby="helpModalLabel"><div class="modal-dialog" role="document" style="width:1000px;height:800px;"><div class="modal-content"></div></div></div><div class="modal" id="loaderModal" tabindex="-1" role="dialog" aria-labelledby="loaderModalLabel"><div class="modal-dialog" role="document" style="width:1000px;height:800px;"><div class="modal-content"><div class="modal-body"><div id="leafy_loader"></div><p class="text-center text-muted" id="leafy_loader_text">Loading ... please wait ...</p><p class="text-center" id="leafy_loader_close_btn" style="display:none"><button type="button" class="btn btn-primary" data-dismiss="modal" style> Close</button></p></div></div></div></div><script src="/static/js/jquery.min.js"></script><script src="/static/js/bootstrap.min.js"></script><script src="/static/js/stupidtable.min.js"></script><script src="/static/js/TweenMax.min.js"></script><script src="/static/js/jquery.qtip.min.js"></script><script src="/static/js/planet_loader.js"></script><script> function init_qtip() { $('.qtip_tooltip').each(function() { $(this).qtip({ content: { text: function(event, api) { $.ajax({ url: api.elements.target.attr('qtip_href') }) .then(function(content) { // Set the tooltip content upon successful retrieval api.set('content.text', content); 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