Mp1g01200.1

Description : UPF1 Nonsense-Mediated mRNA Decay effector protein

Gene families : OG_42_0003239 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0003239_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Marchantia polymorpha: Mp1g01200.1
Cluster	HCAA Clusters: Cluster_13

Target	Alias	Description	ECC score	Gene Family Method
Cre01.g040379	No alias	RNA helicase, putative	0.03	Orthogroups_2024-Update
MA_10426702g0020	No alias	(at5g47010 : 144.0) Required for nonsense-mediated mRNA...	0.02	Orthogroups_2024-Update
Solyc08g007110	No alias	Regulator of nonsense transcripts 1 homolog (AHRD V3.3...	0.02	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
BP	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	IEA	16Dec
BP	GO:0000956	nuclear-transcribed mRNA catabolic process	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	IEA	16Dec
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004386	helicase activity	IEA	16Dec
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	16Dec
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005737	cytoplasm	IEA	16Dec
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006401	RNA catabolic process	None	Extended
BP	GO:0006402	mRNA catabolic process	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0008270	zinc ion binding	IEA	16Dec
BP	GO:0009056	catabolic process	None	Extended
BP	GO:0009057	macromolecule catabolic process	None	Extended
BP	GO:0009892	negative regulation of metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0010468	regulation of gene expression	None	Extended
BP	GO:0010605	negative regulation of macromolecule metabolic process	None	Extended
BP	GO:0010629	negative regulation of gene expression	None	Extended
BP	GO:0016070	RNA metabolic process	None	Extended
BP	GO:0016071	mRNA metabolic process	None	Extended
MF	GO:0016462	pyrophosphatase activity	None	Extended
MF	GO:0016787	hydrolase activity	IEA	16Dec
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	None	Extended
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0017111	nucleoside-triphosphatase activity	None	Extended
BP	GO:0019222	regulation of metabolic process	None	Extended
BP	GO:0019439	aromatic compound catabolic process	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034655	nucleobase-containing compound catabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
MF	GO:0043169	cation binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044248	cellular catabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0044265	cellular macromolecule catabolic process	None	Extended
BP	GO:0044270	cellular nitrogen compound catabolic process	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0046700	heterocycle catabolic process	None	Extended
MF	GO:0046872	metal ion binding	None	Extended
MF	GO:0046914	transition metal ion binding	None	Extended
BP	GO:0048519	negative regulation of biological process	None	Extended
BP	GO:0050789	regulation of biological process	None	Extended
BP	GO:0060255	regulation of macromolecule metabolic process	None	Extended
BP	GO:0065007	biological regulation	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
BP	GO:1901361	organic cyclic compound catabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901575	organic substance catabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0001505	regulation of neurotransmitter levels	IEP	Predicted GO
MF	GO:0003684	damaged DNA binding	IEP	Predicted GO
MF	GO:0003712	transcription coregulator activity	IEP	Predicted GO
MF	GO:0004356	glutamate-ammonia ligase activity	IEP	Predicted GO
MF	GO:0004371	glycerone kinase activity	IEP	Predicted GO
MF	GO:0004375	glycine dehydrogenase (decarboxylating) activity	IEP	Predicted GO
BP	GO:0006066	alcohol metabolic process	IEP	Predicted GO
BP	GO:0006071	glycerol metabolic process	IEP	Predicted GO
BP	GO:0006357	regulation of transcription by RNA polymerase II	IEP	Predicted GO
BP	GO:0006544	glycine metabolic process	IEP	Predicted GO
BP	GO:0006546	glycine catabolic process	IEP	Predicted GO
BP	GO:0006813	potassium ion transport	IEP	Predicted GO
MF	GO:0008374	O-acyltransferase activity	IEP	Predicted GO
BP	GO:0009063	cellular amino acid catabolic process	IEP	Predicted GO
BP	GO:0009069	serine family amino acid metabolic process	IEP	Predicted GO
BP	GO:0009071	serine family amino acid catabolic process	IEP	Predicted GO
MF	GO:0015298	solute:cation antiporter activity	IEP	Predicted GO
MF	GO:0015299	solute:proton antiporter activity	IEP	Predicted GO
BP	GO:0016054	organic acid catabolic process	IEP	Predicted GO
MF	GO:0016211	ammonia ligase activity	IEP	Predicted GO
CC	GO:0016592	mediator complex	IEP	Predicted GO
MF	GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	IEP	Predicted GO
MF	GO:0016642	oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor	IEP	Predicted GO
MF	GO:0016880	acid-ammonia (or amide) ligase activity	IEP	Predicted GO
BP	GO:0019400	alditol metabolic process	IEP	Predicted GO
BP	GO:0019751	polyol metabolic process	IEP	Predicted GO
MF	GO:0019843	rRNA binding	IEP	Predicted GO
MF	GO:0022804	active transmembrane transporter activity	IEP	Predicted GO
BP	GO:0042133	neurotransmitter metabolic process	IEP	Predicted GO
BP	GO:0042135	neurotransmitter catabolic process	IEP	Predicted GO
BP	GO:0042737	drug catabolic process	IEP	Predicted GO
BP	GO:0046395	carboxylic acid catabolic process	IEP	Predicted GO
BP	GO:1901606	alpha-amino acid catabolic process	IEP	Predicted GO
BP	GO:1901615	organic hydroxy compound metabolic process	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR006935	Helicase/UvrB_N	476	541
IPR018999	RNA-helicase_UPF1_UPF2-interct	124	276

External Links

No external refs found!

Mp1g01200.1

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation