evm.model.tig00000158.16

Description : (at4g21710 : 946.0) Encodes the unique second-largest subunit of DNA-dependent RNA polymerase II; the ortholog of budding yeast RPB2 and a homolog of the E. coli RNA polymerase beta subunit.; NRPB2; CONTAINS InterPro DOMAIN/s: DNA-directed RNA polymerase, subunit 2, domain 6 (InterPro:IPR007120), RNA polymerase Rpb2, domain 7 (InterPro:IPR007641), RNA polymerase, beta subunit, protrusion (InterPro:IPR007644), RNA polymerase Rpb2, domain 3 (InterPro:IPR007645), DNA-directed RNA polymerase, subunit 2 (InterPro:IPR015712), RNA polymerase Rpb2, domain 2 (InterPro:IPR007642), RNA polymerase Rpb2, domain 4 (InterPro:IPR007646), RNA polymerase, beta subunit, conserved site (InterPro:IPR007121), RNA polymerase Rpb2, domain 5 (InterPro:IPR007647); BEST Arabidopsis thaliana protein match is: nuclear RNA polymerase C2 (TAIR:AT5G45140.1); Has 37546 Blast hits to 27868 proteins in 9192 species: Archae - 496; Bacteria - 17572; Metazoa - 623; Fungi - 7193; Plants - 3397; Viruses - 232; Other Eukaryotes - 8033 (source: NCBI BLink). & (q8ma12|rpob_chagl : 144.0) DNA-directed RNA polymerase beta chain (EC 2.7.7.6) (PEP) (Plastid-encoded RNA polymerase subunit beta) (RNA polymerase subunit beta) - Chaetosphaeridium globosum & (reliability: 1892.0) & (original description: no original description)

Gene families : OG_42_0000798 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000798_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Cyanophora release: evm.model.tig00000158.16
Cluster	HCCA clusters: Cluster_61

Target	Alias	Description	ECC score	Gene Family Method
148107	No alias	DNA-directed RNA polymerase family protein	0.03	Orthogroups_2024-Update
At3g18090	No alias	nuclear RNA polymerase D2B [Source:TAIR;Acc:AT3G18090]	0.02	Orthogroups_2024-Update
At4g21710	No alias	DNA-directed RNA polymerase II subunit 2...	0.03	Orthogroups_2024-Update
At5g45140	No alias	DNA-directed RNA polymerase III subunit 2...	0.02	Orthogroups_2024-Update
Bradi1g13720	No alias	DNA-directed RNA polymerase family protein	0.02	Orthogroups_2024-Update
Brara.C04571.1	No alias	component *(NRPB2) of RNA polymerase II complex	0.02	Orthogroups_2024-Update
Cre02.g075150	No alias	DNA-directed RNA polymerase family protein	0.04	Orthogroups_2024-Update
Cre12.g542800	No alias	nuclear RNA polymerase C2	0.02	Orthogroups_2024-Update
Glyma.15G172100	No alias	DNA-directed RNA polymerase family protein	0.04	Orthogroups_2024-Update
Kfl00016_0440	kfl00016_0440_v1.1	(at4g21710 : 1847.0) Encodes the unique second-largest...	0.02	Orthogroups_2024-Update
LOC_Os03g44484	No alias	DNA-directed RNA polymerase II subunit RPB2, putative, expressed	0.01	Orthogroups_2024-Update
Mp4g21160.1	No alias	subunit 2 of Pol II RNA polymerase	0.02	Orthogroups_2024-Update
PSME_00007346-RA	No alias	(at4g21710 : 1979.0) Encodes the unique second-largest...	0.01	Orthogroups_2024-Update
Seita.1G002700.1	No alias	component *(NRPC2) of RNA polymerase III complex	0.01	Orthogroups_2024-Update
Seita.9G156200.1	No alias	component *(NRPB2) of RNA polymerase II complex	0.03	Orthogroups_2024-Update
Sopen02g023120	No alias	RNA polymerase Rpb2, domain 6	0.01	Orthogroups_2024-Update
evm.model.contig_3581.1	No alias	(at4g21710 : 1212.0) Encodes the unique second-largest...	0.02	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	IEA	InterProScan predictions
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003899	DNA-directed 5'-3' RNA polymerase activity	IEA	InterProScan predictions
MF	GO:0005488	binding	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006351	transcription, DNA-templated	IEA	InterProScan predictions
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009059	macromolecule biosynthetic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016070	RNA metabolic process	None	Extended
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016772	transferase activity, transferring phosphorus-containing groups	None	Extended
MF	GO:0016779	nucleotidyltransferase activity	None	Extended
BP	GO:0018130	heterocycle biosynthetic process	None	Extended
BP	GO:0019438	aromatic compound biosynthetic process	None	Extended
BP	GO:0032774	RNA biosynthetic process	None	Extended
MF	GO:0034062	5'-3' RNA polymerase activity	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034645	cellular macromolecule biosynthetic process	None	Extended
BP	GO:0034654	nucleobase-containing compound biosynthetic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0044271	cellular nitrogen compound biosynthetic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
BP	GO:0097659	nucleic acid-templated transcription	None	Extended
MF	GO:0097747	RNA polymerase activity	None	Extended
MF	GO:0140098	catalytic activity, acting on RNA	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
BP	GO:1901362	organic cyclic compound biosynthetic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
CC	GO:0000151	ubiquitin ligase complex	IEP	Predicted GO
MF	GO:0000166	nucleotide binding	IEP	Predicted GO
BP	GO:0000375	RNA splicing, via transesterification reactions	IEP	Predicted GO
BP	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	IEP	Predicted GO
BP	GO:0000398	mRNA splicing, via spliceosome	IEP	Predicted GO
CC	GO:0000439	transcription factor TFIIH core complex	IEP	Predicted GO
MF	GO:0001671	ATPase activator activity	IEP	Predicted GO
MF	GO:0003682	chromatin binding	IEP	Predicted GO
MF	GO:0004672	protein kinase activity	IEP	Predicted GO
MF	GO:0005085	guanyl-nucleotide exchange factor activity	IEP	Predicted GO
MF	GO:0005086	ARF guanyl-nucleotide exchange factor activity	IEP	Predicted GO
MF	GO:0005524	ATP binding	IEP	Predicted GO
CC	GO:0005667	transcription factor complex	IEP	Predicted GO
BP	GO:0006289	nucleotide-excision repair	IEP	Predicted GO
BP	GO:0006396	RNA processing	IEP	Predicted GO
BP	GO:0006397	mRNA processing	IEP	Predicted GO
BP	GO:0006464	cellular protein modification process	IEP	Predicted GO
BP	GO:0006468	protein phosphorylation	IEP	Predicted GO
BP	GO:0006508	proteolysis	IEP	Predicted GO
BP	GO:0006511	ubiquitin-dependent protein catabolic process	IEP	Predicted GO
MF	GO:0008047	enzyme activator activity	IEP	Predicted GO
MF	GO:0008144	drug binding	IEP	Predicted GO
MF	GO:0008234	cysteine-type peptidase activity	IEP	Predicted GO
BP	GO:0008380	RNA splicing	IEP	Predicted GO
BP	GO:0009056	catabolic process	IEP	Predicted GO
BP	GO:0009057	macromolecule catabolic process	IEP	Predicted GO
BP	GO:0009966	regulation of signal transduction	IEP	Predicted GO
BP	GO:0010646	regulation of cell communication	IEP	Predicted GO
BP	GO:0016071	mRNA metabolic process	IEP	Predicted GO
BP	GO:0016310	phosphorylation	IEP	Predicted GO
BP	GO:0016567	protein ubiquitination	IEP	Predicted GO
MF	GO:0016773	phosphotransferase activity, alcohol group as acceptor	IEP	Predicted GO
MF	GO:0017069	snRNA binding	IEP	Predicted GO
MF	GO:0017070	U6 snRNA binding	IEP	Predicted GO
MF	GO:0017076	purine nucleotide binding	IEP	Predicted GO
BP	GO:0019538	protein metabolic process	IEP	Predicted GO
MF	GO:0019899	enzyme binding	IEP	Predicted GO
BP	GO:0019941	modification-dependent protein catabolic process	IEP	Predicted GO
BP	GO:0023051	regulation of signaling	IEP	Predicted GO
MF	GO:0030554	adenyl nucleotide binding	IEP	Predicted GO
MF	GO:0030623	U5 snRNA binding	IEP	Predicted GO
MF	GO:0031625	ubiquitin protein ligase binding	IEP	Predicted GO
BP	GO:0032012	regulation of ARF protein signal transduction	IEP	Predicted GO
BP	GO:0032446	protein modification by small protein conjugation	IEP	Predicted GO
MF	GO:0032553	ribonucleotide binding	IEP	Predicted GO
MF	GO:0032555	purine ribonucleotide binding	IEP	Predicted GO
MF	GO:0032559	adenyl ribonucleotide binding	IEP	Predicted GO
MF	GO:0034450	ubiquitin-ubiquitin ligase activity	IEP	Predicted GO
MF	GO:0035639	purine ribonucleoside triphosphate binding	IEP	Predicted GO
MF	GO:0036094	small molecule binding	IEP	Predicted GO
BP	GO:0036211	protein modification process	IEP	Predicted GO
MF	GO:0043167	ion binding	IEP	Predicted GO
MF	GO:0043168	anion binding	IEP	Predicted GO
BP	GO:0043412	macromolecule modification	IEP	Predicted GO
BP	GO:0043632	modification-dependent macromolecule catabolic process	IEP	Predicted GO
BP	GO:0044248	cellular catabolic process	IEP	Predicted GO
BP	GO:0044265	cellular macromolecule catabolic process	IEP	Predicted GO
BP	GO:0044267	cellular protein metabolic process	IEP	Predicted GO
MF	GO:0044389	ubiquitin-like protein ligase binding	IEP	Predicted GO
CC	GO:0044798	nuclear transcription factor complex	IEP	Predicted GO
BP	GO:0046578	regulation of Ras protein signal transduction	IEP	Predicted GO
BP	GO:0048583	regulation of response to stimulus	IEP	Predicted GO
MF	GO:0051020	GTPase binding	IEP	Predicted GO
BP	GO:0051056	regulation of small GTPase mediated signal transduction	IEP	Predicted GO
BP	GO:0051603	proteolysis involved in cellular protein catabolic process	IEP	Predicted GO
MF	GO:0060589	nucleoside-triphosphatase regulator activity	IEP	Predicted GO
MF	GO:0060590	ATPase regulator activity	IEP	Predicted GO
MF	GO:0061630	ubiquitin protein ligase activity	IEP	Predicted GO
MF	GO:0061659	ubiquitin-like protein ligase activity	IEP	Predicted GO
BP	GO:0070647	protein modification by small protein conjugation or removal	IEP	Predicted GO
CC	GO:0090575	RNA polymerase II transcription factor complex	IEP	Predicted GO
MF	GO:0097367	carbohydrate derivative binding	IEP	Predicted GO
MF	GO:0098772	molecular function regulator	IEP	Predicted GO
MF	GO:0140096	catalytic activity, acting on a protein	IEP	Predicted GO
MF	GO:1901265	nucleoside phosphate binding	IEP	Predicted GO
BP	GO:1901564	organonitrogen compound metabolic process	IEP	Predicted GO
BP	GO:1901575	organic substance catabolic process	IEP	Predicted GO
BP	GO:1902531	regulation of intracellular signal transduction	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR007645	RNA_pol_Rpb2_3	471	535
IPR007647	RNA_pol_Rpb2_5	638	691
IPR007644	RNA_pol_bsu_protrusion	43	447
IPR007646	RNA_pol_Rpb2_4	570	629
IPR007642	RNA_pol_Rpb2_2	211	399
IPR007120	DNA-dir_RNAP_su2_dom	861	1079
IPR007120	DNA-dir_RNAP_su2_dom	709	758
IPR007641	RNA_pol_Rpb2_7	1081	1151

External Links

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evm.model.tig00000158.16

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation