evm.model.tig00020537.19

Description : (q40545|kpya_tobac : 207.0) Pyruvate kinase isozyme A, chloroplast precursor (EC 2.7.1.40) - Nicotiana tabacum (Common tobacco) & (at3g22960 : 206.0) encodes a chloroplast pyruvate kinase alpha subunit. Important for seed oil biosynthesis. Ubiquitously expressed, with significantly increased expression in maturing seeds.; PKP-ALPHA; FUNCTIONS IN: pyruvate kinase activity; INVOLVED IN: response to cadmium ion, glycolysis, lipid metabolic process; LOCATED IN: chloroplast stroma, chloroplast; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Pyruvate kinase, C-terminal-like (InterPro:IPR015795), Pyruvate kinase, active site (InterPro:IPR018209), Pyruvate kinase, beta-barrel-like (InterPro:IPR011037), Pyruvate kinase, alpha/beta (InterPro:IPR015794), Pyruvate/Phosphoenolpyruvate kinase, catalytic core (InterPro:IPR015813), Pyruvate kinase (InterPro:IPR001697), Pyruvate kinase, barrel (InterPro:IPR015793); BEST Arabidopsis thaliana protein match is: plastidic pyruvate kinase beta subunit 1 (TAIR:AT5G52920.1); Has 10289 Blast hits to 10239 proteins in 2715 species: Archae - 167; Bacteria - 6049; Metazoa - 538; Fungi - 221; Plants - 529; Viruses - 0; Other Eukaryotes - 2785 (source: NCBI BLink). & (reliability: 412.0) & (original description: no original description)

Gene families : OG_42_0000849 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000849_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Cyanophora release: evm.model.tig00020537.19
Cluster	HCCA clusters: Cluster_23

Target	Alias	Description	ECC score	Gene Family Method
A4A49_02970	No alias	plastidial pyruvate kinase 2	0.01	Orthogroups_2024-Update
Bradi1g55500	No alias	Pyruvate kinase family protein	0.02	Orthogroups_2024-Update
Brara.A02688.1	No alias	pyruvate kinase & plastidial pyruvate kinase & EC_2.7...	0.02	Orthogroups_2024-Update
Glyma.20G164500	No alias	plastidic pyruvate kinase beta subunit 1	0.02	Orthogroups_2024-Update
Pp1s284_7V6	No alias	pyruvate kinase	0.03	Orthogroups_2024-Update
Sobic.001G057200.1	No alias	pyruvate kinase & plastidial pyruvate kinase & EC_2.7...	0.01	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0000287	magnesium ion binding	IEA	InterProScan predictions
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004743	pyruvate kinase activity	IEA	InterProScan predictions
MF	GO:0005488	binding	None	Extended
BP	GO:0005975	carbohydrate metabolic process	None	Extended
BP	GO:0006082	organic acid metabolic process	None	Extended
BP	GO:0006090	pyruvate metabolic process	None	Extended
BP	GO:0006091	generation of precursor metabolites and energy	None	Extended
BP	GO:0006096	glycolytic process	IEA	InterProScan predictions
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006163	purine nucleotide metabolic process	None	Extended
BP	GO:0006164	purine nucleotide biosynthetic process	None	Extended
BP	GO:0006165	nucleoside diphosphate phosphorylation	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006732	coenzyme metabolic process	None	Extended
BP	GO:0006733	oxidoreduction coenzyme metabolic process	None	Extended
BP	GO:0006753	nucleoside phosphate metabolic process	None	Extended
BP	GO:0006754	ATP biosynthetic process	None	Extended
BP	GO:0006757	ATP generation from ADP	None	Extended
BP	GO:0006793	phosphorus metabolic process	None	Extended
BP	GO:0006796	phosphate-containing compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009056	catabolic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009108	coenzyme biosynthetic process	None	Extended
BP	GO:0009117	nucleotide metabolic process	None	Extended
BP	GO:0009123	nucleoside monophosphate metabolic process	None	Extended
BP	GO:0009124	nucleoside monophosphate biosynthetic process	None	Extended
BP	GO:0009126	purine nucleoside monophosphate metabolic process	None	Extended
BP	GO:0009127	purine nucleoside monophosphate biosynthetic process	None	Extended
BP	GO:0009132	nucleoside diphosphate metabolic process	None	Extended
BP	GO:0009135	purine nucleoside diphosphate metabolic process	None	Extended
BP	GO:0009141	nucleoside triphosphate metabolic process	None	Extended
BP	GO:0009142	nucleoside triphosphate biosynthetic process	None	Extended
BP	GO:0009144	purine nucleoside triphosphate metabolic process	None	Extended
BP	GO:0009145	purine nucleoside triphosphate biosynthetic process	None	Extended
BP	GO:0009150	purine ribonucleotide metabolic process	None	Extended
BP	GO:0009152	purine ribonucleotide biosynthetic process	None	Extended
BP	GO:0009156	ribonucleoside monophosphate biosynthetic process	None	Extended
BP	GO:0009161	ribonucleoside monophosphate metabolic process	None	Extended
BP	GO:0009165	nucleotide biosynthetic process	None	Extended
BP	GO:0009166	nucleotide catabolic process	None	Extended
BP	GO:0009167	purine ribonucleoside monophosphate metabolic process	None	Extended
BP	GO:0009168	purine ribonucleoside monophosphate biosynthetic process	None	Extended
BP	GO:0009179	purine ribonucleoside diphosphate metabolic process	None	Extended
BP	GO:0009185	ribonucleoside diphosphate metabolic process	None	Extended
BP	GO:0009199	ribonucleoside triphosphate metabolic process	None	Extended
BP	GO:0009201	ribonucleoside triphosphate biosynthetic process	None	Extended
BP	GO:0009205	purine ribonucleoside triphosphate metabolic process	None	Extended
BP	GO:0009206	purine ribonucleoside triphosphate biosynthetic process	None	Extended
BP	GO:0009259	ribonucleotide metabolic process	None	Extended
BP	GO:0009260	ribonucleotide biosynthetic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016052	carbohydrate catabolic process	None	Extended
BP	GO:0016053	organic acid biosynthetic process	None	Extended
BP	GO:0016310	phosphorylation	None	Extended
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016772	transferase activity, transferring phosphorus-containing groups	None	Extended
MF	GO:0016773	phosphotransferase activity, alcohol group as acceptor	None	Extended
BP	GO:0017144	drug metabolic process	None	Extended
BP	GO:0018130	heterocycle biosynthetic process	None	Extended
BP	GO:0019359	nicotinamide nucleotide biosynthetic process	None	Extended
BP	GO:0019362	pyridine nucleotide metabolic process	None	Extended
BP	GO:0019363	pyridine nucleotide biosynthetic process	None	Extended
BP	GO:0019438	aromatic compound biosynthetic process	None	Extended
BP	GO:0019439	aromatic compound catabolic process	None	Extended
BP	GO:0019637	organophosphate metabolic process	None	Extended
BP	GO:0019693	ribose phosphate metabolic process	None	Extended
BP	GO:0019752	carboxylic acid metabolic process	None	Extended
MF	GO:0030955	potassium ion binding	IEA	InterProScan predictions
MF	GO:0031420	alkali metal ion binding	None	Extended
BP	GO:0032787	monocarboxylic acid metabolic process	None	Extended
BP	GO:0034404	nucleobase-containing small molecule biosynthetic process	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034654	nucleobase-containing compound biosynthetic process	None	Extended
BP	GO:0034655	nucleobase-containing compound catabolic process	None	Extended
BP	GO:0042866	pyruvate biosynthetic process	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043169	cation binding	None	Extended
BP	GO:0043436	oxoacid metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044248	cellular catabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044270	cellular nitrogen compound catabolic process	None	Extended
BP	GO:0044271	cellular nitrogen compound biosynthetic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
BP	GO:0044283	small molecule biosynthetic process	None	Extended
BP	GO:0046031	ADP metabolic process	None	Extended
BP	GO:0046034	ATP metabolic process	None	Extended
BP	GO:0046390	ribose phosphate biosynthetic process	None	Extended
BP	GO:0046394	carboxylic acid biosynthetic process	None	Extended
BP	GO:0046434	organophosphate catabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0046496	nicotinamide nucleotide metabolic process	None	Extended
BP	GO:0046700	heterocycle catabolic process	None	Extended
MF	GO:0046872	metal ion binding	None	Extended
BP	GO:0046939	nucleotide phosphorylation	None	Extended
BP	GO:0051186	cofactor metabolic process	None	Extended
BP	GO:0051188	cofactor biosynthetic process	None	Extended
BP	GO:0055086	nucleobase-containing small molecule metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0072330	monocarboxylic acid biosynthetic process	None	Extended
BP	GO:0072521	purine-containing compound metabolic process	None	Extended
BP	GO:0072522	purine-containing compound biosynthetic process	None	Extended
BP	GO:0072524	pyridine-containing compound metabolic process	None	Extended
BP	GO:0072525	pyridine-containing compound biosynthetic process	None	Extended
BP	GO:0090407	organophosphate biosynthetic process	None	Extended
BP	GO:1901135	carbohydrate derivative metabolic process	None	Extended
BP	GO:1901137	carbohydrate derivative biosynthetic process	None	Extended
BP	GO:1901292	nucleoside phosphate catabolic process	None	Extended
BP	GO:1901293	nucleoside phosphate biosynthetic process	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
BP	GO:1901361	organic cyclic compound catabolic process	None	Extended
BP	GO:1901362	organic cyclic compound biosynthetic process	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901566	organonitrogen compound biosynthetic process	None	Extended
BP	GO:1901575	organic substance catabolic process	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

Toggle parental

Type	GO Term	Name	Evidence	Source
BP	GO:0000096	sulfur amino acid metabolic process	IEP	Predicted GO
BP	GO:0000097	sulfur amino acid biosynthetic process	IEP	Predicted GO
BP	GO:0000105	histidine biosynthetic process	IEP	Predicted GO
MF	GO:0000166	nucleotide binding	IEP	Predicted GO
MF	GO:0000295	adenine nucleotide transmembrane transporter activity	IEP	Predicted GO
MF	GO:0003735	structural constituent of ribosome	IEP	Predicted GO
MF	GO:0003746	translation elongation factor activity	IEP	Predicted GO
MF	GO:0004399	histidinol dehydrogenase activity	IEP	Predicted GO
MF	GO:0004512	inositol-3-phosphate synthase activity	IEP	Predicted GO
MF	GO:0004812	aminoacyl-tRNA ligase activity	IEP	Predicted GO
MF	GO:0004817	cysteine-tRNA ligase activity	IEP	Predicted GO
MF	GO:0004827	proline-tRNA ligase activity	IEP	Predicted GO
MF	GO:0005198	structural molecule activity	IEP	Predicted GO
MF	GO:0005346	purine ribonucleotide transmembrane transporter activity	IEP	Predicted GO
MF	GO:0005347	ATP transmembrane transporter activity	IEP	Predicted GO
MF	GO:0005471	ATP:ADP antiporter activity	IEP	Predicted GO
MF	GO:0005524	ATP binding	IEP	Predicted GO
CC	GO:0005575	cellular_component	IEP	Predicted GO
CC	GO:0005622	intracellular	IEP	Predicted GO
CC	GO:0005737	cytoplasm	IEP	Predicted GO
CC	GO:0005840	ribosome	IEP	Predicted GO
BP	GO:0006020	inositol metabolic process	IEP	Predicted GO
BP	GO:0006021	inositol biosynthetic process	IEP	Predicted GO
BP	GO:0006066	alcohol metabolic process	IEP	Predicted GO
BP	GO:0006399	tRNA metabolic process	IEP	Predicted GO
BP	GO:0006412	translation	IEP	Predicted GO
BP	GO:0006414	translational elongation	IEP	Predicted GO
BP	GO:0006418	tRNA aminoacylation for protein translation	IEP	Predicted GO
BP	GO:0006423	cysteinyl-tRNA aminoacylation	IEP	Predicted GO
BP	GO:0006433	prolyl-tRNA aminoacylation	IEP	Predicted GO
BP	GO:0006518	peptide metabolic process	IEP	Predicted GO
BP	GO:0006520	cellular amino acid metabolic process	IEP	Predicted GO
BP	GO:0006547	histidine metabolic process	IEP	Predicted GO
BP	GO:0006555	methionine metabolic process	IEP	Predicted GO
BP	GO:0006629	lipid metabolic process	IEP	Predicted GO
BP	GO:0006644	phospholipid metabolic process	IEP	Predicted GO
BP	GO:0006694	steroid biosynthetic process	IEP	Predicted GO
BP	GO:0006766	vitamin metabolic process	IEP	Predicted GO
BP	GO:0006767	water-soluble vitamin metabolic process	IEP	Predicted GO
BP	GO:0006771	riboflavin metabolic process	IEP	Predicted GO
BP	GO:0006862	nucleotide transport	IEP	Predicted GO
MF	GO:0008144	drug binding	IEP	Predicted GO
MF	GO:0008172	S-methyltransferase activity	IEP	Predicted GO
BP	GO:0008202	steroid metabolic process	IEP	Predicted GO
MF	GO:0008514	organic anion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0008531	riboflavin kinase activity	IEP	Predicted GO
MF	GO:0008565	protein transporter activity	IEP	Predicted GO
BP	GO:0008610	lipid biosynthetic process	IEP	Predicted GO
BP	GO:0008652	cellular amino acid biosynthetic process	IEP	Predicted GO
MF	GO:0008686	3,4-dihydroxy-2-butanone-4-phosphate synthase activity	IEP	Predicted GO
MF	GO:0008705	methionine synthase activity	IEP	Predicted GO
BP	GO:0009059	macromolecule biosynthetic process	IEP	Predicted GO
BP	GO:0009066	aspartate family amino acid metabolic process	IEP	Predicted GO
BP	GO:0009067	aspartate family amino acid biosynthetic process	IEP	Predicted GO
BP	GO:0009086	methionine biosynthetic process	IEP	Predicted GO
BP	GO:0009110	vitamin biosynthetic process	IEP	Predicted GO
BP	GO:0009231	riboflavin biosynthetic process	IEP	Predicted GO
CC	GO:0009507	chloroplast	IEP	Predicted GO
CC	GO:0009536	plastid	IEP	Predicted GO
MF	GO:0015215	nucleotide transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015216	purine nucleotide transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015217	ADP transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015238	drug transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015301	anion:anion antiporter activity	IEP	Predicted GO
MF	GO:0015605	organophosphate ester transmembrane transporter activity	IEP	Predicted GO
BP	GO:0015748	organophosphate ester transport	IEP	Predicted GO
BP	GO:0015931	nucleobase-containing compound transport	IEP	Predicted GO
MF	GO:0015932	nucleobase-containing compound transmembrane transporter activity	IEP	Predicted GO
CC	GO:0016021	integral component of membrane	IEP	Predicted GO
BP	GO:0016070	RNA metabolic process	IEP	Predicted GO
MF	GO:0016462	pyrophosphatase activity	IEP	Predicted GO
MF	GO:0016746	transferase activity, transferring acyl groups	IEP	Predicted GO
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	IEP	Predicted GO
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	IEP	Predicted GO
MF	GO:0016872	intramolecular lyase activity	IEP	Predicted GO
MF	GO:0016874	ligase activity	IEP	Predicted GO
MF	GO:0016875	ligase activity, forming carbon-oxygen bonds	IEP	Predicted GO
MF	GO:0016887	ATPase activity	IEP	Predicted GO
MF	GO:0016987	sigma factor activity	IEP	Predicted GO
BP	GO:0017038	protein import	IEP	Predicted GO
MF	GO:0017076	purine nucleotide binding	IEP	Predicted GO
MF	GO:0017111	nucleoside-triphosphatase activity	IEP	Predicted GO
BP	GO:0019538	protein metabolic process	IEP	Predicted GO
BP	GO:0019751	polyol metabolic process	IEP	Predicted GO
BP	GO:0022613	ribonucleoprotein complex biogenesis	IEP	Predicted GO
BP	GO:0030258	lipid modification	IEP	Predicted GO
MF	GO:0030554	adenyl nucleotide binding	IEP	Predicted GO
CC	GO:0031224	intrinsic component of membrane	IEP	Predicted GO
MF	GO:0032553	ribonucleotide binding	IEP	Predicted GO
MF	GO:0032555	purine ribonucleotide binding	IEP	Predicted GO
MF	GO:0032559	adenyl ribonucleotide binding	IEP	Predicted GO
MF	GO:0032977	membrane insertase activity	IEP	Predicted GO
CC	GO:0032991	protein-containing complex	IEP	Predicted GO
BP	GO:0034645	cellular macromolecule biosynthetic process	IEP	Predicted GO
BP	GO:0034660	ncRNA metabolic process	IEP	Predicted GO
MF	GO:0035639	purine ribonucleoside triphosphate binding	IEP	Predicted GO
MF	GO:0036094	small molecule binding	IEP	Predicted GO
MF	GO:0042084	5-methyltetrahydrofolate-dependent methyltransferase activity	IEP	Predicted GO
BP	GO:0042254	ribosome biogenesis	IEP	Predicted GO
BP	GO:0042364	water-soluble vitamin biosynthetic process	IEP	Predicted GO
BP	GO:0042558	pteridine-containing compound metabolic process	IEP	Predicted GO
BP	GO:0042726	flavin-containing compound metabolic process	IEP	Predicted GO
BP	GO:0042727	flavin-containing compound biosynthetic process	IEP	Predicted GO
BP	GO:0043038	amino acid activation	IEP	Predicted GO
BP	GO:0043039	tRNA aminoacylation	IEP	Predicted GO
BP	GO:0043043	peptide biosynthetic process	IEP	Predicted GO
MF	GO:0043168	anion binding	IEP	Predicted GO
BP	GO:0043170	macromolecule metabolic process	IEP	Predicted GO
CC	GO:0043226	organelle	IEP	Predicted GO
CC	GO:0043228	non-membrane-bounded organelle	IEP	Predicted GO
CC	GO:0043229	intracellular organelle	IEP	Predicted GO
CC	GO:0043232	intracellular non-membrane-bounded organelle	IEP	Predicted GO
BP	GO:0043603	cellular amide metabolic process	IEP	Predicted GO
BP	GO:0043604	amide biosynthetic process	IEP	Predicted GO
BP	GO:0044085	cellular component biogenesis	IEP	Predicted GO
BP	GO:0044255	cellular lipid metabolic process	IEP	Predicted GO
BP	GO:0044260	cellular macromolecule metabolic process	IEP	Predicted GO
BP	GO:0044267	cellular protein metabolic process	IEP	Predicted GO
CC	GO:0044424	intracellular part	IEP	Predicted GO
CC	GO:0044425	membrane part	IEP	Predicted GO
CC	GO:0044444	cytoplasmic part	IEP	Predicted GO
CC	GO:0044464	cell part	IEP	Predicted GO
BP	GO:0046165	alcohol biosynthetic process	IEP	Predicted GO
BP	GO:0046173	polyol biosynthetic process	IEP	Predicted GO
BP	GO:0046834	lipid phosphorylation	IEP	Predicted GO
BP	GO:0046854	phosphatidylinositol phosphorylation	IEP	Predicted GO
MF	GO:0050661	NADP binding	IEP	Predicted GO
MF	GO:0050662	coenzyme binding	IEP	Predicted GO
BP	GO:0052803	imidazole-containing compound metabolic process	IEP	Predicted GO
BP	GO:0071702	organic substance transport	IEP	Predicted GO
BP	GO:0071705	nitrogen compound transport	IEP	Predicted GO
BP	GO:0090304	nucleic acid metabolic process	IEP	Predicted GO
MF	GO:0097159	organic cyclic compound binding	IEP	Predicted GO
MF	GO:0097367	carbohydrate derivative binding	IEP	Predicted GO
MF	GO:0099516	ion antiporter activity	IEP	Predicted GO
MF	GO:0140098	catalytic activity, acting on RNA	IEP	Predicted GO
MF	GO:0140101	catalytic activity, acting on a tRNA	IEP	Predicted GO
MF	GO:1901265	nucleoside phosphate binding	IEP	Predicted GO
MF	GO:1901363	heterocyclic compound binding	IEP	Predicted GO
MF	GO:1901505	carbohydrate derivative transmembrane transporter activity	IEP	Predicted GO
BP	GO:1901605	alpha-amino acid metabolic process	IEP	Predicted GO
BP	GO:1901607	alpha-amino acid biosynthetic process	IEP	Predicted GO
BP	GO:1901615	organic hydroxy compound metabolic process	IEP	Predicted GO
BP	GO:1901617	organic hydroxy compound biosynthetic process	IEP	Predicted GO
CC	GO:1990904	ribonucleoprotein complex	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR015795	Pyrv_Knase_C	479	574
IPR015793	Pyrv_Knase_brl	192	380

External Links

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evm.model.tig00020537.19

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation