evm.model.tig00020563.191

Description : (at4g02570 : 445.0) Encodes a cullin that is a component of SCF ubiquitin ligase complexes involved in mediating responses to auxin and jasmonic acid. Homozygous auxin-resistant mutants arrest growth soon after germination, lacking a root and hypocotyl. Heterozygotes display a variety of phenotypes consistent with impaired auxin response.; cullin 1 (CUL1); CONTAINS InterPro DOMAIN/s: Winged helix-turn-helix transcription repressor DNA-binding (InterPro:IPR011991), Cullin homology (InterPro:IPR016158), Cullin protein, neddylation domain (InterPro:IPR019559), Cullin, conserved site (InterPro:IPR016157), Cullin, N-terminal (InterPro:IPR001373), Cullin repeat-like-containing domain (InterPro:IPR016159); BEST Arabidopsis thaliana protein match is: cullin 2 (TAIR:AT1G02980.1). & (reliability: 890.0) & (original description: no original description)

Gene families : OG_42_0000877 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000877_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Cyanophora release: evm.model.tig00020563.191
Cluster	HCCA clusters: Cluster_61

Target	Alias	Description	ECC score	Gene Family Method
173394	No alias	cullin 1	0.04	Orthogroups_2024-Update
At4g02570	No alias	AT4G02570 protein [Source:UniProtKB/TrEMBL;Acc:B9DGE3]	0.02	Orthogroups_2024-Update
Bradi2g35820	No alias	cullin 1	0.02	Orthogroups_2024-Update
Bradi2g35830	No alias	cullin 1	0.01	Orthogroups_2024-Update
Glyma.09G046500	No alias	cullin 1	0.04	Orthogroups_2024-Update
LOC_Os05g05700	No alias	cullin, putative, expressed	0.01	Orthogroups_2024-Update
Mp8g03110.1	No alias	scaffold component CUL1/CUL2 of SKP1-CUL1-FBX (SCF) E3...	0.01	Orthogroups_2024-Update
Potri.008G224075	No alias	cullin 1	0.01	Orthogroups_2024-Update
Potri.010G023800	No alias	cullin 1	0.01	Orthogroups_2024-Update
Seita.3G037700.1	No alias	scaffold component *(CUL1) of SCF E3 ubiquitin ligase complexes	0.05	Orthogroups_2024-Update
Sobic.009G044800.1	No alias	scaffold component *(CUL1) of SCF E3 ubiquitin ligase complexes	0.04	Orthogroups_2024-Update
Solyc09g074680	No alias	cullin 1 (AHRD V3.3 *** AT4G02570.4)	0.01	Orthogroups_2024-Update
Sopen06g035900	No alias	Cullin family	0.02	Orthogroups_2024-Update
evm.model.contig_2038.1	No alias	(at4g02570 : 261.0) Encodes a cullin that is a component...	0.03	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005515	protein binding	None	Extended
BP	GO:0006508	proteolysis	None	Extended
BP	GO:0006511	ubiquitin-dependent protein catabolic process	IEA	InterProScan predictions
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009056	catabolic process	None	Extended
BP	GO:0009057	macromolecule catabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0019538	protein metabolic process	None	Extended
MF	GO:0019899	enzyme binding	None	Extended
BP	GO:0019941	modification-dependent protein catabolic process	None	Extended
MF	GO:0031625	ubiquitin protein ligase binding	IEA	InterProScan predictions
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0043632	modification-dependent macromolecule catabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044248	cellular catabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0044265	cellular macromolecule catabolic process	None	Extended
MF	GO:0044389	ubiquitin-like protein ligase binding	None	Extended
BP	GO:0051603	proteolysis involved in cellular protein catabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901575	organic substance catabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
CC	GO:0000151	ubiquitin ligase complex	IEP	Predicted GO
CC	GO:0000159	protein phosphatase type 2A complex	IEP	Predicted GO
MF	GO:0000166	nucleotide binding	IEP	Predicted GO
BP	GO:0000375	RNA splicing, via transesterification reactions	IEP	Predicted GO
BP	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	IEP	Predicted GO
BP	GO:0000398	mRNA splicing, via spliceosome	IEP	Predicted GO
CC	GO:0000439	transcription factor TFIIH core complex	IEP	Predicted GO
MF	GO:0001671	ATPase activator activity	IEP	Predicted GO
MF	GO:0004357	glutamate-cysteine ligase activity	IEP	Predicted GO
MF	GO:0005085	guanyl-nucleotide exchange factor activity	IEP	Predicted GO
MF	GO:0005086	ARF guanyl-nucleotide exchange factor activity	IEP	Predicted GO
MF	GO:0005524	ATP binding	IEP	Predicted GO
CC	GO:0005575	cellular_component	IEP	Predicted GO
CC	GO:0005667	transcription factor complex	IEP	Predicted GO
CC	GO:0005801	cis-Golgi network	IEP	Predicted GO
BP	GO:0006289	nucleotide-excision repair	IEP	Predicted GO
BP	GO:0006575	cellular modified amino acid metabolic process	IEP	Predicted GO
BP	GO:0006749	glutathione metabolic process	IEP	Predicted GO
BP	GO:0006750	glutathione biosynthetic process	IEP	Predicted GO
BP	GO:0006810	transport	IEP	Predicted GO
BP	GO:0006886	intracellular protein transport	IEP	Predicted GO
BP	GO:0006888	ER to Golgi vesicle-mediated transport	IEP	Predicted GO
MF	GO:0008047	enzyme activator activity	IEP	Predicted GO
BP	GO:0008104	protein localization	IEP	Predicted GO
MF	GO:0008144	drug binding	IEP	Predicted GO
MF	GO:0008234	cysteine-type peptidase activity	IEP	Predicted GO
CC	GO:0008287	protein serine/threonine phosphatase complex	IEP	Predicted GO
BP	GO:0008380	RNA splicing	IEP	Predicted GO
BP	GO:0009966	regulation of signal transduction	IEP	Predicted GO
BP	GO:0010646	regulation of cell communication	IEP	Predicted GO
BP	GO:0015031	protein transport	IEP	Predicted GO
BP	GO:0015833	peptide transport	IEP	Predicted GO
BP	GO:0016192	vesicle-mediated transport	IEP	Predicted GO
BP	GO:0016567	protein ubiquitination	IEP	Predicted GO
MF	GO:0016881	acid-amino acid ligase activity	IEP	Predicted GO
MF	GO:0017076	purine nucleotide binding	IEP	Predicted GO
BP	GO:0019184	nonribosomal peptide biosynthetic process	IEP	Predicted GO
MF	GO:0019208	phosphatase regulator activity	IEP	Predicted GO
MF	GO:0019888	protein phosphatase regulator activity	IEP	Predicted GO
BP	GO:0023051	regulation of signaling	IEP	Predicted GO
CC	GO:0030117	membrane coat	IEP	Predicted GO
CC	GO:0030120	vesicle coat	IEP	Predicted GO
CC	GO:0030126	COPI vesicle coat	IEP	Predicted GO
CC	GO:0030127	COPII vesicle coat	IEP	Predicted GO
MF	GO:0030234	enzyme regulator activity	IEP	Predicted GO
MF	GO:0030554	adenyl nucleotide binding	IEP	Predicted GO
BP	GO:0032012	regulation of ARF protein signal transduction	IEP	Predicted GO
BP	GO:0032446	protein modification by small protein conjugation	IEP	Predicted GO
MF	GO:0032553	ribonucleotide binding	IEP	Predicted GO
MF	GO:0032555	purine ribonucleotide binding	IEP	Predicted GO
MF	GO:0032559	adenyl ribonucleotide binding	IEP	Predicted GO
CC	GO:0032991	protein-containing complex	IEP	Predicted GO
BP	GO:0033036	macromolecule localization	IEP	Predicted GO
MF	GO:0034450	ubiquitin-ubiquitin ligase activity	IEP	Predicted GO
MF	GO:0035639	purine ribonucleoside triphosphate binding	IEP	Predicted GO
BP	GO:0042398	cellular modified amino acid biosynthetic process	IEP	Predicted GO
BP	GO:0042886	amide transport	IEP	Predicted GO
MF	GO:0043168	anion binding	IEP	Predicted GO
CC	GO:0044422	organelle part	IEP	Predicted GO
CC	GO:0044424	intracellular part	IEP	Predicted GO
CC	GO:0044425	membrane part	IEP	Predicted GO
CC	GO:0044431	Golgi apparatus part	IEP	Predicted GO
CC	GO:0044433	cytoplasmic vesicle part	IEP	Predicted GO
CC	GO:0044444	cytoplasmic part	IEP	Predicted GO
CC	GO:0044446	intracellular organelle part	IEP	Predicted GO
CC	GO:0044464	cell part	IEP	Predicted GO
CC	GO:0044798	nuclear transcription factor complex	IEP	Predicted GO
BP	GO:0045184	establishment of protein localization	IEP	Predicted GO
BP	GO:0046578	regulation of Ras protein signal transduction	IEP	Predicted GO
BP	GO:0046907	intracellular transport	IEP	Predicted GO
BP	GO:0048193	Golgi vesicle transport	IEP	Predicted GO
BP	GO:0048583	regulation of response to stimulus	IEP	Predicted GO
BP	GO:0051056	regulation of small GTPase mediated signal transduction	IEP	Predicted GO
BP	GO:0051179	localization	IEP	Predicted GO
BP	GO:0051234	establishment of localization	IEP	Predicted GO
BP	GO:0051641	cellular localization	IEP	Predicted GO
BP	GO:0051649	establishment of localization in cell	IEP	Predicted GO
MF	GO:0060590	ATPase regulator activity	IEP	Predicted GO
MF	GO:0061630	ubiquitin protein ligase activity	IEP	Predicted GO
MF	GO:0061659	ubiquitin-like protein ligase activity	IEP	Predicted GO
BP	GO:0070647	protein modification by small protein conjugation or removal	IEP	Predicted GO
BP	GO:0071702	organic substance transport	IEP	Predicted GO
BP	GO:0071705	nitrogen compound transport	IEP	Predicted GO
CC	GO:0090575	RNA polymerase II transcription factor complex	IEP	Predicted GO
MF	GO:0097367	carbohydrate derivative binding	IEP	Predicted GO
MF	GO:0098772	molecular function regulator	IEP	Predicted GO
CC	GO:0098796	membrane protein complex	IEP	Predicted GO
MF	GO:1901265	nucleoside phosphate binding	IEP	Predicted GO
CC	GO:1902494	catalytic complex	IEP	Predicted GO
BP	GO:1902531	regulation of intracellular signal transduction	IEP	Predicted GO
CC	GO:1903293	phosphatase complex	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR001373	Cullin_N	33	511

External Links

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evm.model.tig00020563.191

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation