Description : (at1g70660 : 112.0) MMZ2/UEV1B encodes a protein that may play a role in DNA damage responses and error-free post-replicative DNA repair by participating in lysine-63-based polyubiquitination reactions. UEV1A can form diubiquitin and triubiquitin chains in combination with UBC13A/UBC35 in vitro. It can also functionally complement an mms2 mutation in budding yeast, both by increasing mms2 mutant viability in the presence of the DNA damaging agent MMS, and by reducing the rate of spontaneous DNA mutation. However, a combination of MMZ2/UEV1B and UBC13A do not do a good job of rescuing an mms2 ubc13 double mutant in yeast. MMZ2/UEV1B transcripts are found in most plant organs, but not in the pollen or in seedlings 6 hours or 2 days post-germination. The transcript levels do not appear to be stress-inducible.; MMS ZWEI homologue 2 (MMZ2); CONTAINS InterPro DOMAIN/s: Ubiquitin-conjugating enzyme/RWD-like (InterPro:IPR016135), Ubiquitin-conjugating enzyme, E2 (InterPro:IPR000608); BEST Arabidopsis thaliana protein match is: Ran BP2/NZF zinc finger-like superfamily protein (TAIR:AT1G70650.2). & (reliability: 218.0) & (original description: no original description)
Gene families : OG_42_0001236 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0001236_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Cyanophora release: evm.model.tig00020703.8 | |
Cluster | HCCA clusters: Cluster_21 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
Glyma.19G197500 | No alias | MMS ZWEI homologue 3 | 0.02 | Orthogroups_2024-Update | |
Mp8g00620.1 | No alias | component Uev1 of Ubc13-Uev1 conjugating E2 complex | 0.01 | Orthogroups_2024-Update | |
Solyc01g007860 | No alias | ubiquitin-conjugating enzyme E2 variant 1D | 0.02 | Orthogroups_2024-Update | |
Solyc10g083120 | No alias | Ubiquitin-conjugating enzyme, E2 (AHRD V3.3 *** A0A103XCT0_CYNCS) | 0.02 | Orthogroups_2024-Update |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No GO annotation available for this sequence |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0003712 | transcription coregulator activity | IEP | Predicted GO |
MF | GO:0005319 | lipid transporter activity | IEP | Predicted GO |
MF | GO:0005548 | phospholipid transporter activity | IEP | Predicted GO |
BP | GO:0006357 | regulation of transcription by RNA polymerase II | IEP | Predicted GO |
BP | GO:0006810 | transport | IEP | Predicted GO |
BP | GO:0006820 | anion transport | IEP | Predicted GO |
BP | GO:0006869 | lipid transport | IEP | Predicted GO |
BP | GO:0007034 | vacuolar transport | IEP | Predicted GO |
BP | GO:0015711 | organic anion transport | IEP | Predicted GO |
BP | GO:0015748 | organophosphate ester transport | IEP | Predicted GO |
BP | GO:0015914 | phospholipid transport | IEP | Predicted GO |
CC | GO:0016592 | mediator complex | IEP | Predicted GO |
CC | GO:0044451 | nucleoplasm part | IEP | Predicted GO |
CC | GO:0044464 | cell part | IEP | Predicted GO |
BP | GO:0051179 | localization | IEP | Predicted GO |
BP | GO:0051234 | establishment of localization | IEP | Predicted GO |
MF | GO:0140110 | transcription regulator activity | IEP | Predicted GO |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR000608 | UBQ-conjugat_E2 | 28 | 86 |
No external refs found! |