evm.model.tig00021108.30

Description : (at3g44530 : 310.0) Encodes a nuclear localized WD-repeat containing protein involved in negative regulation of knox gene expression via epigenetic mechanism of chromatin re-organization. Interacts physically and genetically with AS1. Expressed in meristem and leaf primordia. Homozygous mutants are embryo lethal. Phenotype of cosuppressed lines is variable but show effects on leaf development similar to as1/as2.; homolog of histone chaperone HIRA (HIRA); CONTAINS InterPro DOMAIN/s: WD40 repeat 2 (InterPro:IPR019782), TUP1-like enhancer of split (InterPro:IPR011494), WD40 repeat, conserved site (InterPro:IPR019775), WD40 repeat (InterPro:IPR001680), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: Transducin/WD40 repeat-like superfamily protein (TAIR:AT5G64630.2). & (p93107|pf20_chlre : 80.1) Flagellar WD repeat protein PF20 - Chlamydomonas reinhardtii & (reliability: 620.0) & (original description: no original description)

Gene families : OG_42_0005271 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0005271_tree

Sequence : coding (download), protein (download)

Attention: This gene has low abundance.

Download

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Cyanophora release: evm.model.tig00021108.30
Cluster	HCCA clusters: Cluster_6

Target	Alias	Description	ECC score	Gene Family Method	Actions
Cre13.g575950	No alias	homolog of histone chaperone HIRA	0.02	Orthogroups_2024-Update
GRMZM2G167161	No alias	homolog of histone chaperone HIRA	0.02	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005515	protein binding	IEA	InterProScan predictions
BP	GO:0006355	regulation of transcription, DNA-templated	IEA	InterProScan predictions
BP	GO:0008150	biological_process	None	Extended
BP	GO:0009889	regulation of biosynthetic process	None	Extended
BP	GO:0010468	regulation of gene expression	None	Extended
BP	GO:0010556	regulation of macromolecule biosynthetic process	None	Extended
BP	GO:0019219	regulation of nucleobase-containing compound metabolic process	None	Extended
BP	GO:0019222	regulation of metabolic process	None	Extended
BP	GO:0031323	regulation of cellular metabolic process	None	Extended
BP	GO:0031326	regulation of cellular biosynthetic process	None	Extended
BP	GO:0050789	regulation of biological process	None	Extended
BP	GO:0050794	regulation of cellular process	None	Extended
BP	GO:0051171	regulation of nitrogen compound metabolic process	None	Extended
BP	GO:0051252	regulation of RNA metabolic process	None	Extended
BP	GO:0060255	regulation of macromolecule metabolic process	None	Extended
BP	GO:0065007	biological regulation	None	Extended
BP	GO:0080090	regulation of primary metabolic process	None	Extended
BP	GO:1903506	regulation of nucleic acid-templated transcription	None	Extended
BP	GO:2000112	regulation of cellular macromolecule biosynthetic process	None	Extended
BP	GO:2001141	regulation of RNA biosynthetic process	None	Extended

Toggle parental

Type	GO Term	Name	Evidence	Source
CC	GO:0000151	ubiquitin ligase complex	IEP	Predicted GO
CC	GO:0000152	nuclear ubiquitin ligase complex	IEP	Predicted GO
CC	GO:0000808	origin recognition complex	IEP	Predicted GO
MF	GO:0003677	DNA binding	IEP	Predicted GO
MF	GO:0003682	chromatin binding	IEP	Predicted GO
MF	GO:0003916	DNA topoisomerase activity	IEP	Predicted GO
MF	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity	IEP	Predicted GO
MF	GO:0004144	diacylglycerol O-acyltransferase activity	IEP	Predicted GO
CC	GO:0005664	nuclear origin of replication recognition complex	IEP	Predicted GO
CC	GO:0005667	transcription factor complex	IEP	Predicted GO
CC	GO:0005680	anaphase-promoting complex	IEP	Predicted GO
BP	GO:0006259	DNA metabolic process	IEP	Predicted GO
BP	GO:0006260	DNA replication	IEP	Predicted GO
BP	GO:0006265	DNA topological change	IEP	Predicted GO
BP	GO:0006298	mismatch repair	IEP	Predicted GO
MF	GO:0008094	DNA-dependent ATPase activity	IEP	Predicted GO
MF	GO:0008168	methyltransferase activity	IEP	Predicted GO
MF	GO:0008374	O-acyltransferase activity	IEP	Predicted GO
MF	GO:0008963	phospho-N-acetylmuramoyl-pentapeptide-transferase activity	IEP	Predicted GO
MF	GO:0016411	acylglycerol O-acyltransferase activity	IEP	Predicted GO
MF	GO:0016740	transferase activity	IEP	Predicted GO
MF	GO:0016780	phosphotransferase activity, for other substituted phosphate groups	IEP	Predicted GO
MF	GO:0030983	mismatched DNA binding	IEP	Predicted GO
CC	GO:0031461	cullin-RING ubiquitin ligase complex	IEP	Predicted GO
BP	GO:0043170	macromolecule metabolic process	IEP	Predicted GO
BP	GO:0044260	cellular macromolecule metabolic process	IEP	Predicted GO
CC	GO:0044428	nuclear part	IEP	Predicted GO
CC	GO:0044454	nuclear chromosome part	IEP	Predicted GO
BP	GO:0045017	glycerolipid biosynthetic process	IEP	Predicted GO
MF	GO:0061505	DNA topoisomerase II activity	IEP	Predicted GO
MF	GO:0140097	catalytic activity, acting on DNA	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR011494	Hira	692	893
IPR001680	WD40_repeat	45	64
IPR001680	WD40_repeat	145	174
IPR001680	WD40_repeat	10	41
IPR001680	WD40_repeat	88	122

External Links

No external refs found!

evm.model.tig00021108.30

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation