Description : (p35016|enpl_catro : 328.0) Endoplasmin homolog precursor (GRP94 homolog) - Catharanthus roseus (Rosy periwinkle) (Madagascar periwinkle) & (at4g24190 : 321.0) encodes an ortholog of GRP94, an ER-resident HSP90-like protein and is involved in regulation of meristem size and organization. Single and double mutant analyses suggest that SHD may be required for the correct folding and/or complex formation of CLV proteins. Lines carrying recessive mutations in this locus exhibits expanded shoot meristems, disorganized root meristems, and defective pollen tube elongation. Transcript is detected in all tissues examined and is not induced by heat. Endoplasmin supports the protein secretory pathway and has a role in proliferating tissues.; SHEPHERD (SHD); FUNCTIONS IN: unfolded protein binding, ATP binding; INVOLVED IN: in 8 processes; LOCATED IN: in 6 components; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: Chaperone protein htpG (InterPro:IPR001404), Heat shock protein Hsp90, C-terminal (InterPro:IPR020576), Heat shock protein Hsp90, N-terminal (InterPro:IPR020575), Molecular chaperone, heat shock protein, endoplasmin (InterPro:IPR015566), ATPase-like, ATP-binding domain (InterPro:IPR003594), Heat shock protein Hsp90, conserved site (InterPro:IPR019805), Ribosomal protein S5 domain 2-type fold (InterPro:IPR020568); BEST Arabidopsis thaliana protein match is: heat shock protein 90.1 (TAIR:AT5G52640.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). & (reliability: 642.0) & (original description: no original description)
Gene families : OG_42_0000360 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000360_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
| Type | Description | Actions |
|---|---|---|
| Neighborhood | Cyanophora release: evm.model.tig00021126.11 | |
| Cluster | HCCA clusters: Cluster_77 |
| Target | Alias | Description | ECC score | Gene Family Method | Actions |
|---|---|---|---|---|---|
| At5g56000 | No alias | Hsp81.4 [Source:UniProtKB/TrEMBL;Acc:A0A178UQ52] | 0.02 | Orthogroups_2024-Update | |
| At5g56030 | No alias | Heat shock protein 81-2 [Source:UniProtKB/TrEMBL;Acc:F4K6B6] | 0.03 | Orthogroups_2024-Update | |
| Bradi1g30130 | No alias | Chaperone protein htpG family protein | 0.03 | Orthogroups_2024-Update | |
| Bradi3g39620 | No alias | HEAT SHOCK PROTEIN 81.4 | 0.01 | Orthogroups_2024-Update | |
| Bradi3g39630 | No alias | HEAT SHOCK PROTEIN 81.4 | 0.02 | Orthogroups_2024-Update | |
| Brara.C01247.1 | No alias | chaperone *(Hsp90) | 0.01 | Orthogroups_2024-Update | |
| Brara.I02117.1 | No alias | chaperone *(Hsp90) | 0.02 | Orthogroups_2024-Update | |
| Cre02.g080650 | No alias | Chaperone protein htpG family protein | 0.04 | Orthogroups_2024-Update | |
| Cre09.g386750 | No alias | HEAT SHOCK PROTEIN 81.4 | 0.02 | Orthogroups_2024-Update | |
| GRMZM2G069651 | No alias | HEAT SHOCK PROTEIN 81.4 | 0.01 | Orthogroups_2024-Update | |
| GRMZM5G813217 | No alias | Chaperone protein htpG family protein | 0.01 | Orthogroups_2024-Update | |
| Glyma.02G302500 | No alias | HEAT SHOCK PROTEIN 81.4 | 0.03 | Orthogroups_2024-Update | |
| Glyma.14G219700 | No alias | Chaperone protein htpG family protein | 0.02 | Orthogroups_2024-Update | |
| Glyma.17G258700 | No alias | Chaperone protein htpG family protein | 0.03 | Orthogroups_2024-Update | |
| HORVU7Hr1G117000.1 | No alias | chaperone *(Hsp90) | 0.03 | Orthogroups_2024-Update | |
| Kfl00416_0110 | kfl00416_0110_v1.1 | (at4g24190 : 832.0) encodes an ortholog of GRP94, an... | 0.02 | Orthogroups_2024-Update | |
| MA_10431770g0010 | No alias | (at2g04030 : 1110.0) Encodes a chloroplast-targeted... | 0.01 | Orthogroups_2024-Update | |
| MA_12191g0010 | No alias | (at5g56030 : 1080.0) A member of heat shock protein 90... | 0.02 | Orthogroups_2024-Update | |
| Mp2g04900.1 | No alias | chaperone (Hsp90) | 0.02 | Orthogroups_2024-Update | |
| PSME_00002089-RA | No alias | (at5g52640 : 409.0) Encodes a cytosolic heat shock... | 0.02 | Orthogroups_2024-Update | |
| PSME_00005303-RA | No alias | (at2g04030 : 1018.0) Encodes a chloroplast-targeted... | 0.03 | Orthogroups_2024-Update | |
| PSME_00010812-RA | No alias | (p35016|enpl_catro : 974.0) Endoplasmin homolog... | 0.03 | Orthogroups_2024-Update | |
| PSME_00046532-RA | No alias | (at5g52640 : 404.0) Encodes a cytosolic heat shock... | 0.02 | Orthogroups_2024-Update | |
| Potri.001G286700 | No alias | HEAT SHOCK PROTEIN 81.4 | 0.01 | Orthogroups_2024-Update | |
| Potri.001G466000 | No alias | HEAT SHOCK PROTEIN 81.4 | 0.02 | Orthogroups_2024-Update | |
| Potri.005G241100 | No alias | Chaperone protein htpG family protein | 0.02 | Orthogroups_2024-Update | |
| Potri.006G002800 | No alias | HEAT SHOCK PROTEIN 81.4 | 0.02 | Orthogroups_2024-Update | |
| Seita.4G281500.1 | No alias | chaperone *(Hsp90) | 0.02 | Orthogroups_2024-Update | |
| Sobic.007G216300.1 | No alias | chaperone *(Hsp90) | 0.01 | Orthogroups_2024-Update | |
| Sobic.010G267400.1 | No alias | chaperone *(Hsp90) | 0.02 | Orthogroups_2024-Update | |
| Solyc04g081570 | No alias | Heat shock protein 90 (AHRD V3.3 *** G9MD87_TOBAC) | 0.02 | Orthogroups_2024-Update | |
| Sopen04g035180 | No alias | Hsp90 protein | 0.03 | Orthogroups_2024-Update | |
| Sopen12g007780 | No alias | Hsp90 protein | 0.02 | Orthogroups_2024-Update | |
| evm.model.contig_601.1 | No alias | (at5g56030 : 902.0) A member of heat shock protein 90... | 0.03 | Orthogroups_2024-Update |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
| MF | GO:0005524 | ATP binding | IEA | InterProScan predictions |
| BP | GO:0006457 | protein folding | IEA | InterProScan predictions |
| MF | GO:0051082 | unfolded protein binding | IEA | InterProScan predictions |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
| MF | GO:0004784 | superoxide dismutase activity | IEP | Predicted GO |
| MF | GO:0004857 | enzyme inhibitor activity | IEP | Predicted GO |
| MF | GO:0004864 | protein phosphatase inhibitor activity | IEP | Predicted GO |
| MF | GO:0005096 | GTPase activator activity | IEP | Predicted GO |
| CC | GO:0005783 | endoplasmic reticulum | IEP | Predicted GO |
| CC | GO:0005787 | signal peptidase complex | IEP | Predicted GO |
| BP | GO:0006465 | signal peptide processing | IEP | Predicted GO |
| BP | GO:0006801 | superoxide metabolic process | IEP | Predicted GO |
| MF | GO:0008047 | enzyme activator activity | IEP | Predicted GO |
| BP | GO:0009144 | purine nucleoside triphosphate metabolic process | IEP | Predicted GO |
| BP | GO:0009199 | ribonucleoside triphosphate metabolic process | IEP | Predicted GO |
| BP | GO:0009205 | purine ribonucleoside triphosphate metabolic process | IEP | Predicted GO |
| BP | GO:0009966 | regulation of signal transduction | IEP | Predicted GO |
| BP | GO:0010646 | regulation of cell communication | IEP | Predicted GO |
| BP | GO:0010921 | regulation of phosphatase activity | IEP | Predicted GO |
| BP | GO:0016070 | RNA metabolic process | IEP | Predicted GO |
| MF | GO:0016209 | antioxidant activity | IEP | Predicted GO |
| BP | GO:0016485 | protein processing | IEP | Predicted GO |
| MF | GO:0016721 | oxidoreductase activity, acting on superoxide radicals as acceptor | IEP | Predicted GO |
| MF | GO:0016765 | transferase activity, transferring alkyl or aryl (other than methyl) groups | IEP | Predicted GO |
| MF | GO:0019208 | phosphatase regulator activity | IEP | Predicted GO |
| MF | GO:0019212 | phosphatase inhibitor activity | IEP | Predicted GO |
| BP | GO:0019220 | regulation of phosphate metabolic process | IEP | Predicted GO |
| MF | GO:0019888 | protein phosphatase regulator activity | IEP | Predicted GO |
| BP | GO:0023051 | regulation of signaling | IEP | Predicted GO |
| MF | GO:0030234 | enzyme regulator activity | IEP | Predicted GO |
| MF | GO:0030695 | GTPase regulator activity | IEP | Predicted GO |
| BP | GO:0031399 | regulation of protein modification process | IEP | Predicted GO |
| BP | GO:0032268 | regulation of cellular protein metabolic process | IEP | Predicted GO |
| BP | GO:0034220 | ion transmembrane transport | IEP | Predicted GO |
| BP | GO:0034641 | cellular nitrogen compound metabolic process | IEP | Predicted GO |
| BP | GO:0035303 | regulation of dephosphorylation | IEP | Predicted GO |
| BP | GO:0035304 | regulation of protein dephosphorylation | IEP | Predicted GO |
| MF | GO:0043169 | cation binding | IEP | Predicted GO |
| BP | GO:0043666 | regulation of phosphoprotein phosphatase activity | IEP | Predicted GO |
| CC | GO:0044432 | endoplasmic reticulum part | IEP | Predicted GO |
| CC | GO:0044444 | cytoplasmic part | IEP | Predicted GO |
| BP | GO:0046034 | ATP metabolic process | IEP | Predicted GO |
| MF | GO:0046872 | metal ion binding | IEP | Predicted GO |
| MF | GO:0046983 | protein dimerization activity | IEP | Predicted GO |
| BP | GO:0048583 | regulation of response to stimulus | IEP | Predicted GO |
| BP | GO:0050790 | regulation of catalytic activity | IEP | Predicted GO |
| BP | GO:0051174 | regulation of phosphorus metabolic process | IEP | Predicted GO |
| BP | GO:0051246 | regulation of protein metabolic process | IEP | Predicted GO |
| BP | GO:0051336 | regulation of hydrolase activity | IEP | Predicted GO |
| BP | GO:0051604 | protein maturation | IEP | Predicted GO |
| MF | GO:0060589 | nucleoside-triphosphatase regulator activity | IEP | Predicted GO |
| BP | GO:0065009 | regulation of molecular function | IEP | Predicted GO |
| BP | GO:0072593 | reactive oxygen species metabolic process | IEP | Predicted GO |
| BP | GO:0098655 | cation transmembrane transport | IEP | Predicted GO |
| BP | GO:0098660 | inorganic ion transmembrane transport | IEP | Predicted GO |
| BP | GO:0098662 | inorganic cation transmembrane transport | IEP | Predicted GO |
| MF | GO:0098772 | molecular function regulator | IEP | Predicted GO |
| BP | GO:1902600 | proton transmembrane transport | IEP | Predicted GO |
| CC | GO:1905368 | peptidase complex | IEP | Predicted GO |
| No external refs found! |