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- Kfl00373_0010
Kfl00373_0010 (kfl00373_0010_v1.1)
Aliases : kfl00373_0010_v1.1
Description : (at5g37500 : 281.0) Encodes a guard cell outward potassium channel. Belongs to the Shaker family K+ channel. This family includes five groups based on phylogenetic analysis (FEBS Letters (2007) 581: 2357): I (inward rectifying channel): AKT1 (AT2G26650), AKT5 (AT4G32500) and SPIK (also known as AKT6, AT2G25600); II (inward rectifying channel): KAT1 (AT5G46240) and KAT2 (AT4G18290); III (weakly inward rectifying channel): AKT2 (AT4G22200); IV (regulatory subunit involved in inwardly rectifying conductance formation): KAT3 (also known as AtKC1, AT4G32650); V (outward rectifying channel): SKOR (AT3G02850) and GORK (AT5G37500). Mutants have increased water consumption and limited stomatal closure in response to abscisic and jasmonic acids. It forms a heteromeric K(out) channels with SKOR. The gene is expressed ubiquitously in root and the vasculature and guard cells of leaves. Expression is suppressed during agrobacterium-induced tumor formation and increased in response to water deprivation and cold.; gated outwardly-rectifying K+ channel (GORK); FUNCTIONS IN: outward rectifier potassium channel activity, cyclic nucleotide binding, protein binding; INVOLVED IN: response to jasmonic acid stimulus, response to water deprivation, response to cold, response to abscisic acid stimulus; LOCATED IN: nucleus; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 7 growth stages; CONTAINS InterPro DOMAIN/s: Cyclic nucleotide-binding (InterPro:IPR000595), Potassium channel, voltage-dependent, EAG/ELK/ERG (InterPro:IPR003938), Protein of unknown function DUF3354 (InterPro:IPR021789), Ankyrin repeat-containing domain (InterPro:IPR020683), Ion transport (InterPro:IPR005821), Cyclic nucleotide-binding-like (InterPro:IPR018490), RmlC-like jelly roll fold (InterPro:IPR014710), Ankyrin repeat (InterPro:IPR002110); BEST Arabidopsis thaliana protein match is: STELAR K+ outward rectifier (TAIR:AT3G02850.1); Has 84212 Blast hits to 35106 proteins in 1650 species: Archae - 146; Bacteria - 9486; Metazoa - 40206; Fungi - 7878; Plants - 3819; Viruses - 1287; Other Eukaryotes - 21390 (source: NCBI BLink). & (q8vyx2|akt1_orysa : 273.0) Potassium channel AKT1 (OsAKT1) - Oryza sativa (Rice) & (reliability: 562.0) & (original description: no original description)
Expression Profile
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Co-expression Networks
| Type | Description | Actions |
| Neighborhood | Klebsormidium release: Kfl00373_0010 | |
| Cluster | HCCA clusters: Cluster_59 | |
Expression Context Conservation (ECC)
| Target | Alias | Description | ECC score | Gene Family Method | Actions |
| Bradi2g45170 | No alias | K+ transporter 1 | 0.04 | Orthogroups_2024-Update | |
| Brara.H00948.1 | No alias | voltage-gated potassium cation channel *(AKT/SKOR/GORK) | 0.01 | Orthogroups_2024-Update | |
| Glyma.08G232100 | No alias | potassium channel in Arabidopsis thaliana 1 | 0.02 | Orthogroups_2024-Update | |
| LOC_Os03g28120 | No alias | potassium channel protein, putative, expressed | 0.01 | Orthogroups_2024-Update | |
| LOC_Os05g35410 | No alias | potassium channel AKT2/3, putative, expressed | 0.01 | Orthogroups_2024-Update | |
| MA_7331g0010 | No alias | (at3g02850 : 965.0) Encodes SKOR, a member of Shaker... | 0.03 | Orthogroups_2024-Update | |
| Potri.018G071400 | No alias | K+ transporter 1 | 0.01 | Orthogroups_2024-Update | |
Functional Annotation
| Type | GO Term | Name | Evidence | Source |
| MF | GO:0003674 | molecular_function | None | Extended |
| MF | GO:0005215 | transporter activity | None | Extended |
| MF | GO:0005216 | ion channel activity | IEA | InterProScan predictions |
| CC | GO:0005575 | cellular_component | None | Extended |
| BP | GO:0006810 | transport | None | Extended |
| BP | GO:0006811 | ion transport | IEA | InterProScan predictions |
| BP | GO:0008150 | biological_process | None | Extended |
| MF | GO:0015075 | ion transmembrane transporter activity | None | Extended |
| MF | GO:0015267 | channel activity | None | Extended |
| MF | GO:0015318 | inorganic molecular entity transmembrane transporter activity | None | Extended |
| CC | GO:0016020 | membrane | IEA | InterProScan predictions |
| MF | GO:0022803 | passive transmembrane transporter activity | None | Extended |
| MF | GO:0022838 | substrate-specific channel activity | None | Extended |
| MF | GO:0022857 | transmembrane transporter activity | None | Extended |
| BP | GO:0051179 | localization | None | Extended |
| BP | GO:0051234 | establishment of localization | None | Extended |
| BP | GO:0055085 | transmembrane transport | IEA | InterProScan predictions |
| Type | GO Term | Name | Evidence | Source |
| MF | GO:0003980 | UDP-glucose:glycoprotein glucosyltransferase activity | IEP | Predicted GO |
| MF | GO:0005096 | GTPase activator activity | IEP | Predicted GO |
| MF | GO:0008047 | enzyme activator activity | IEP | Predicted GO |
| MF | GO:0008194 | UDP-glycosyltransferase activity | IEP | Predicted GO |
| BP | GO:0030001 | metal ion transport | IEP | Predicted GO |
| MF | GO:0030234 | enzyme regulator activity | IEP | Predicted GO |
| MF | GO:0030695 | GTPase regulator activity | IEP | Predicted GO |
| MF | GO:0035251 | UDP-glucosyltransferase activity | IEP | Predicted GO |
| MF | GO:0046527 | glucosyltransferase activity | IEP | Predicted GO |
| MF | GO:0046873 | metal ion transmembrane transporter activity | IEP | Predicted GO |
| MF | GO:0060589 | nucleoside-triphosphatase regulator activity | IEP | Predicted GO |
| MF | GO:0098772 | molecular function regulator | IEP | Predicted GO |
| InterPro domains | Description | Start | Stop |
| IPR005821 | Ion_trans_dom | 126 | 348 |
| IPR000595 | cNMP-bd_dom | 443 | 524 |
| IPR020683 | Ankyrin_rpt-contain_dom | 576 | 663 |
