Kfl00461_0020 (kfl00461_0020_v1.1)

Aliases : kfl00461_0020_v1.1

Description : (at3g28860 : 1090.0) Belongs to the family of ATP-binding cassette (ABC) transporters. Also known as AtMDR11 and PGP19. Possibly regulates auxin-dependent responses by influencing basipetal auxin transport in the root. Acts upstream of phyA in regulating hypocotyl elongation and gravitropic response. Exerts nonredundant, partially overlapping functions with the ABC transporter encoded by AtPGP1.; ATP binding cassette subfamily B19 (ABCB19); FUNCTIONS IN: ATPase activity, coupled to transmembrane movement of substances, auxin efflux transmembrane transporter activity; INVOLVED IN: in 14 processes; LOCATED IN: plasma membrane; EXPRESSED IN: 28 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ABC transporter-like (InterPro:IPR003439), ABC transporter, transmembrane domain, type 1 (InterPro:IPR011527), ABC transporter integral membrane type 1 (InterPro:IPR017940), ABC transporter, transmembrane domain (InterPro:IPR001140), ABC transporter, conserved site (InterPro:IPR017871); BEST Arabidopsis thaliana protein match is: ATP binding cassette subfamily B1 (TAIR:AT2G36910.1); Has 832220 Blast hits to 388750 proteins in 4155 species: Archae - 14331; Bacteria - 653917; Metazoa - 17455; Fungi - 11958; Plants - 9253; Viruses - 33; Other Eukaryotes - 125273 (source: NCBI BLink). & (q6yuu5|mdr_orysa : 548.0) Putative multidrug resistance protein (P-glycoprotein) - Oryza sativa (Rice) & (reliability: 2180.0) & (original description: no original description)

Gene families : OG_42_0000040 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000040_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Klebsormidium release: Kfl00461_0020
Cluster	HCCA clusters: Cluster_59

Target	Alias	Description	ECC score	Gene Family Method
139408	No alias	P-glycoprotein 20	0.02	Orthogroups_2024-Update
A4A49_35042	No alias	abc transporter b family member 1	0.02	Orthogroups_2024-Update
At3g28860	No alias	ABC transporter B family member 19...	0.02	Orthogroups_2024-Update
Bradi1g66290	No alias	P-glycoprotein 20	0.02	Orthogroups_2024-Update
Bradi2g11210	No alias	P-glycoprotein 21	0.01	Orthogroups_2024-Update
Bradi2g47337	No alias	ATP binding cassette subfamily B4	0.02	Orthogroups_2024-Update
Bradi2g47400	No alias	ATP binding cassette subfamily B4	0.02	Orthogroups_2024-Update
Bradi2g47410	No alias	ATP binding cassette subfamily B4	0.02	Orthogroups_2024-Update
GRMZM5G843537	No alias	P-glycoprotein 11	0.02	Orthogroups_2024-Update
Glyma.01G016500	No alias	P-glycoprotein 2	0.02	Orthogroups_2024-Update
Glyma.19G184300	No alias	ATP binding cassette subfamily B1	0.02	Orthogroups_2024-Update
LOC_Os03g17180	No alias	ABC transporter, ATP-binding protein, putative, expressed	0.01	Orthogroups_2024-Update
LOC_Os05g04610	No alias	ABC transporter, ATP-binding protein, putative, expressed	0.02	Orthogroups_2024-Update
MA_14136g0010	No alias	(at2g39480 : 909.0) P-glycoprotein 6 (PGP6); FUNCTIONS...	0.02	Orthogroups_2024-Update
MA_3437g0010	No alias	(at3g28345 : 1374.0) ABC transporter family protein;...	0.01	Orthogroups_2024-Update
MA_644g0010	No alias	(at2g47000 : 703.0) Multidrug resistance P-glycoprotein...	0.01	Orthogroups_2024-Update
Mp1g26440.1	No alias	subfamily ABCB transporter	0.01	Orthogroups_2024-Update
PSME_00011041-RA	No alias	(at4g25960 : 1546.0) P-glycoprotein 2 (PGP2); FUNCTIONS...	0.01	Orthogroups_2024-Update
PSME_00014276-RA	No alias	(at3g55320 : 2001.0) P-glycoprotein 20 (PGP20);...	0.02	Orthogroups_2024-Update
PSME_00023484-RA	No alias	(at2g36910 : 1766.0) Belongs to the family of...	0.02	Orthogroups_2024-Update
PSME_00039275-RA	No alias	(at3g28345 : 1459.0) ABC transporter family protein;...	0.01	Orthogroups_2024-Update
PSME_00043262-RA	No alias	(at3g28345 : 1088.0) ABC transporter family protein;...	0.02	Orthogroups_2024-Update
PSME_00046830-RA	No alias	(at3g28345 : 1028.0) ABC transporter family protein;...	0.01	Orthogroups_2024-Update
Pp1s391_45V6	No alias	multidrug pheromone mdr abc transporter family	0.02	Orthogroups_2024-Update
Seita.5G302200.1	No alias	subfamily ABCB transporter	0.03	Orthogroups_2024-Update
Seita.9G449100.1	No alias	subfamily ABCB transporter	0.02	Orthogroups_2024-Update
Sobic.003G445500.1	No alias	subfamily ABCB transporter	0.02	Orthogroups_2024-Update
Sobic.007G163800.1	No alias	subfamily ABCB transporter	0.02	Orthogroups_2024-Update
evm.model.contig_618.5	No alias	(at2g47000 : 919.0) Multidrug resistance P-glycoprotein...	0.02	Orthogroups_2024-Update
evm.model.tig00000741.4	No alias	(at3g62150 : 432.0) P-glycoprotein 21 (PGP21); FUNCTIONS...	0.01	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0005215	transporter activity	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	InterProScan predictions
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0006810	transport	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
MF	GO:0015399	primary active transmembrane transporter activity	None	Extended
MF	GO:0015405	P-P-bond-hydrolysis-driven transmembrane transporter activity	None	Extended
CC	GO:0016021	integral component of membrane	IEA	InterProScan predictions
MF	GO:0016462	pyrophosphatase activity	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	None	Extended
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	None	Extended
MF	GO:0016887	ATPase activity	IEA	InterProScan predictions
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0017111	nucleoside-triphosphatase activity	None	Extended
MF	GO:0022804	active transmembrane transporter activity	None	Extended
MF	GO:0022857	transmembrane transporter activity	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
CC	GO:0031224	intrinsic component of membrane	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0042623	ATPase activity, coupled	None	Extended
MF	GO:0042626	ATPase activity, coupled to transmembrane movement of substances	IEA	InterProScan predictions
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
MF	GO:0043492	ATPase activity, coupled to movement of substances	None	Extended
CC	GO:0044425	membrane part	None	Extended
BP	GO:0051179	localization	None	Extended
BP	GO:0051234	establishment of localization	None	Extended
BP	GO:0055085	transmembrane transport	IEA	InterProScan predictions
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
CC	GO:0000159	protein phosphatase type 2A complex	IEP	Predicted GO
MF	GO:0004842	ubiquitin-protein transferase activity	IEP	Predicted GO
MF	GO:0005049	nuclear export signal receptor activity	IEP	Predicted GO
BP	GO:0006778	porphyrin-containing compound metabolic process	IEP	Predicted GO
BP	GO:0006787	porphyrin-containing compound catabolic process	IEP	Predicted GO
BP	GO:0006811	ion transport	IEP	Predicted GO
BP	GO:0006812	cation transport	IEP	Predicted GO
BP	GO:0006814	sodium ion transport	IEP	Predicted GO
BP	GO:0006886	intracellular protein transport	IEP	Predicted GO
BP	GO:0006888	ER to Golgi vesicle-mediated transport	IEP	Predicted GO
BP	GO:0006904	vesicle docking involved in exocytosis	IEP	Predicted GO
BP	GO:0008104	protein localization	IEP	Predicted GO
CC	GO:0008287	protein serine/threonine phosphatase complex	IEP	Predicted GO
MF	GO:0010277	chlorophyllide a oxygenase [overall] activity	IEP	Predicted GO
BP	GO:0015031	protein transport	IEP	Predicted GO
MF	GO:0015075	ion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015077	monovalent inorganic cation transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015078	proton transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015318	inorganic molecular entity transmembrane transporter activity	IEP	Predicted GO
BP	GO:0015672	monovalent inorganic cation transport	IEP	Predicted GO
BP	GO:0015833	peptide transport	IEP	Predicted GO
BP	GO:0015988	energy coupled proton transmembrane transport, against electrochemical gradient	IEP	Predicted GO
BP	GO:0015991	ATP hydrolysis coupled proton transport	IEP	Predicted GO
BP	GO:0015994	chlorophyll metabolic process	IEP	Predicted GO
BP	GO:0015996	chlorophyll catabolic process	IEP	Predicted GO
BP	GO:0016192	vesicle-mediated transport	IEP	Predicted GO
BP	GO:0016197	endosomal transport	IEP	Predicted GO
BP	GO:0016482	cytosolic transport	IEP	Predicted GO
MF	GO:0016703	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)	IEP	Predicted GO
MF	GO:0019208	phosphatase regulator activity	IEP	Predicted GO
MF	GO:0019787	ubiquitin-like protein transferase activity	IEP	Predicted GO
MF	GO:0019888	protein phosphatase regulator activity	IEP	Predicted GO
BP	GO:0022406	membrane docking	IEP	Predicted GO
MF	GO:0022890	inorganic cation transmembrane transporter activity	IEP	Predicted GO
CC	GO:0030120	vesicle coat	IEP	Predicted GO
CC	GO:0030127	COPII vesicle coat	IEP	Predicted GO
BP	GO:0033015	tetrapyrrole catabolic process	IEP	Predicted GO
BP	GO:0033036	macromolecule localization	IEP	Predicted GO
CC	GO:0033179	proton-transporting V-type ATPase, V0 domain	IEP	Predicted GO
BP	GO:0042147	retrograde transport, endosome to Golgi	IEP	Predicted GO
BP	GO:0042440	pigment metabolic process	IEP	Predicted GO
BP	GO:0042886	amide transport	IEP	Predicted GO
BP	GO:0045184	establishment of protein localization	IEP	Predicted GO
BP	GO:0046149	pigment catabolic process	IEP	Predicted GO
BP	GO:0046907	intracellular transport	IEP	Predicted GO
MF	GO:0047746	chlorophyllase activity	IEP	Predicted GO
BP	GO:0048278	vesicle docking	IEP	Predicted GO
BP	GO:0051187	cofactor catabolic process	IEP	Predicted GO
BP	GO:0051640	organelle localization	IEP	Predicted GO
BP	GO:0051641	cellular localization	IEP	Predicted GO
BP	GO:0051649	establishment of localization in cell	IEP	Predicted GO
BP	GO:0090662	ATP hydrolysis coupled transmembrane transport	IEP	Predicted GO
BP	GO:0099131	ATP hydrolysis coupled ion transmembrane transport	IEP	Predicted GO
BP	GO:0099132	ATP hydrolysis coupled cation transmembrane transport	IEP	Predicted GO
BP	GO:0140029	exocytic process	IEP	Predicted GO
BP	GO:0140056	organelle localization by membrane tethering	IEP	Predicted GO
MF	GO:0140096	catalytic activity, acting on a protein	IEP	Predicted GO
MF	GO:0140104	molecular carrier activity	IEP	Predicted GO
MF	GO:0140142	nucleocytoplasmic carrier activity	IEP	Predicted GO
CC	GO:1903293	phosphatase complex	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR011527	ABC1_TM_dom	109	380
IPR011527	ABC1_TM_dom	747	1018
IPR003439	ABC_transporter-like	1088	1235
IPR003439	ABC_transporter-like	449	597

External Links

No external refs found!

Kfl00461_0020 (kfl00461_0020_v1.1)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation