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- Kfl00489_0140
Kfl00489_0140 (kfl00489_0140_v1.1)
Aliases : kfl00489_0140_v1.1
Description : (at2g04842 : 817.0) Encodes a dual localized threonyl-tRNA synthetase found both in the mitochondrion and the chloroplast. Plants mutated in this gene terminate as embryos in the globular stage.; EMBRYO DEFECTIVE 2761 (EMB2761); FUNCTIONS IN: ligase activity, forming aminoacyl-tRNA and related compounds, nucleotide binding, aminoacyl-tRNA ligase activity, threonine-tRNA ligase activity, ATP binding; INVOLVED IN: threonyl-tRNA aminoacylation, embryo development ending in seed dormancy; LOCATED IN: mitochondrion, chloroplast stroma, chloroplast; CONTAINS InterPro DOMAIN/s: Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain (InterPro:IPR018163), Threonyl-tRNA synthetase, class IIa (InterPro:IPR002320), Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved domain (InterPro:IPR002314), Aminoacyl-tRNA synthetase, class II, conserved domain (InterPro:IPR006195), Threonyl/alanyl tRNA synthetase, SAD (InterPro:IPR012947), Anticodon-binding (InterPro:IPR004154), Threonyl-tRNA synthetase, class IIa, conserved region (InterPro:IPR018158); BEST Arabidopsis thaliana protein match is: Threonyl-tRNA synthetase (TAIR:AT5G26830.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (reliability: 1634.0) & (original description: no original description)
Expression Profile
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Co-expression Networks
| Type | Description | Actions |
| Neighborhood | Klebsormidium release: Kfl00489_0140 | |
| Cluster | HCCA clusters: Cluster_59 | |
Expression Context Conservation (ECC)
| Target | Alias | Description | ECC score | Gene Family Method | Actions |
| evm.model.tig00021537.23 | No alias | (at5g26830 : 698.0) Encodes a dual-targeted... | 0.02 | Orthogroups_2024-Update | |
Functional Annotation
| Type | GO Term | Name | Evidence | Source |
| MF | GO:0000166 | nucleotide binding | IEA | InterProScan predictions |
| MF | GO:0003674 | molecular_function | None | Extended |
| MF | GO:0003824 | catalytic activity | None | Extended |
| MF | GO:0004812 | aminoacyl-tRNA ligase activity | IEA | InterProScan predictions |
| MF | GO:0005488 | binding | None | Extended |
| MF | GO:0005524 | ATP binding | IEA | InterProScan predictions |
| BP | GO:0006082 | organic acid metabolic process | None | Extended |
| BP | GO:0006139 | nucleobase-containing compound metabolic process | None | Extended |
| BP | GO:0006399 | tRNA metabolic process | None | Extended |
| BP | GO:0006418 | tRNA aminoacylation for protein translation | IEA | InterProScan predictions |
| BP | GO:0006520 | cellular amino acid metabolic process | None | Extended |
| BP | GO:0006725 | cellular aromatic compound metabolic process | None | Extended |
| BP | GO:0006807 | nitrogen compound metabolic process | None | Extended |
| MF | GO:0008144 | drug binding | None | Extended |
| BP | GO:0008150 | biological_process | None | Extended |
| BP | GO:0008152 | metabolic process | None | Extended |
| BP | GO:0009987 | cellular process | None | Extended |
| BP | GO:0016070 | RNA metabolic process | None | Extended |
| MF | GO:0016874 | ligase activity | None | Extended |
| MF | GO:0016875 | ligase activity, forming carbon-oxygen bonds | None | Extended |
| MF | GO:0017076 | purine nucleotide binding | None | Extended |
| BP | GO:0019752 | carboxylic acid metabolic process | None | Extended |
| MF | GO:0030554 | adenyl nucleotide binding | None | Extended |
| MF | GO:0032553 | ribonucleotide binding | None | Extended |
| MF | GO:0032555 | purine ribonucleotide binding | None | Extended |
| MF | GO:0032559 | adenyl ribonucleotide binding | None | Extended |
| BP | GO:0034641 | cellular nitrogen compound metabolic process | None | Extended |
| BP | GO:0034660 | ncRNA metabolic process | None | Extended |
| MF | GO:0035639 | purine ribonucleoside triphosphate binding | None | Extended |
| MF | GO:0036094 | small molecule binding | None | Extended |
| BP | GO:0043038 | amino acid activation | None | Extended |
| BP | GO:0043039 | tRNA aminoacylation | IEA | InterProScan predictions |
| MF | GO:0043167 | ion binding | None | Extended |
| MF | GO:0043168 | anion binding | None | Extended |
| BP | GO:0043170 | macromolecule metabolic process | None | Extended |
| BP | GO:0043436 | oxoacid metabolic process | None | Extended |
| BP | GO:0044237 | cellular metabolic process | None | Extended |
| BP | GO:0044238 | primary metabolic process | None | Extended |
| BP | GO:0044281 | small molecule metabolic process | None | Extended |
| BP | GO:0046483 | heterocycle metabolic process | None | Extended |
| BP | GO:0071704 | organic substance metabolic process | None | Extended |
| BP | GO:0090304 | nucleic acid metabolic process | None | Extended |
| MF | GO:0097159 | organic cyclic compound binding | None | Extended |
| MF | GO:0097367 | carbohydrate derivative binding | None | Extended |
| MF | GO:0140098 | catalytic activity, acting on RNA | None | Extended |
| MF | GO:0140101 | catalytic activity, acting on a tRNA | None | Extended |
| MF | GO:1901265 | nucleoside phosphate binding | None | Extended |
| BP | GO:1901360 | organic cyclic compound metabolic process | None | Extended |
| MF | GO:1901363 | heterocyclic compound binding | None | Extended |
| BP | GO:1901564 | organonitrogen compound metabolic process | None | Extended |
| Type | GO Term | Name | Evidence | Source |
| MF | GO:0000049 | tRNA binding | IEP | Predicted GO |
| BP | GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | IEP | Predicted GO |
| BP | GO:0000956 | nuclear-transcribed mRNA catabolic process | IEP | Predicted GO |
| MF | GO:0003676 | nucleic acid binding | IEP | Predicted GO |
| MF | GO:0003682 | chromatin binding | IEP | Predicted GO |
| MF | GO:0004222 | metalloendopeptidase activity | IEP | Predicted GO |
| MF | GO:0004721 | phosphoprotein phosphatase activity | IEP | Predicted GO |
| MF | GO:0004797 | thymidine kinase activity | IEP | Predicted GO |
| CC | GO:0005634 | nucleus | IEP | Predicted GO |
| CC | GO:0005739 | mitochondrion | IEP | Predicted GO |
| BP | GO:0006338 | chromatin remodeling | IEP | Predicted GO |
| BP | GO:0006401 | RNA catabolic process | IEP | Predicted GO |
| BP | GO:0006402 | mRNA catabolic process | IEP | Predicted GO |
| BP | GO:0006904 | vesicle docking involved in exocytosis | IEP | Predicted GO |
| MF | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity | IEP | Predicted GO |
| BP | GO:0009892 | negative regulation of metabolic process | IEP | Predicted GO |
| BP | GO:0010605 | negative regulation of macromolecule metabolic process | IEP | Predicted GO |
| BP | GO:0010629 | negative regulation of gene expression | IEP | Predicted GO |
| BP | GO:0016311 | dephosphorylation | IEP | Predicted GO |
| MF | GO:0019136 | deoxynucleoside kinase activity | IEP | Predicted GO |
| MF | GO:0019205 | nucleobase-containing compound kinase activity | IEP | Predicted GO |
| MF | GO:0019206 | nucleoside kinase activity | IEP | Predicted GO |
| BP | GO:0022406 | membrane docking | IEP | Predicted GO |
| MF | GO:0031491 | nucleosome binding | IEP | Predicted GO |
| BP | GO:0043044 | ATP-dependent chromatin remodeling | IEP | Predicted GO |
| CC | GO:0043226 | organelle | IEP | Predicted GO |
| CC | GO:0043227 | membrane-bounded organelle | IEP | Predicted GO |
| CC | GO:0043229 | intracellular organelle | IEP | Predicted GO |
| CC | GO:0043231 | intracellular membrane-bounded organelle | IEP | Predicted GO |
| MF | GO:0044877 | protein-containing complex binding | IEP | Predicted GO |
| BP | GO:0048278 | vesicle docking | IEP | Predicted GO |
| BP | GO:0051640 | organelle localization | IEP | Predicted GO |
| BP | GO:0140029 | exocytic process | IEP | Predicted GO |
| BP | GO:0140056 | organelle localization by membrane tethering | IEP | Predicted GO |
