MA_10435713g0020


Description : (at5g19400 : 479.0) Encodes SMG7, a protein that possesses an evolutionarily conserved EST1 domain and exhibits strong homology to human SMG6 (EST1A) and SMG7 (EST1C) proteins. SMG7 plays an evolutionarily conserved role in nonsense-mediated RNA decay (NMD). Required for exit from meiosis. Hypomorphic smg7 alleles render mutant plants sterile by causing an unusual cell-cycle arrest in anaphase II that is characterized by delayed chromosome decondensation and aberrant rearrangement of the meiotic spindle. Disruption of SMG7 causes embryonic lethality.; SMG7; FUNCTIONS IN: molecular_function unknown; INVOLVED IN: meiosis, spindle assembly involved in meiosis, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; LOCATED IN: cellular_component unknown; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Telomerase activating protein Est1 (InterPro:IPR019458); BEST Arabidopsis thaliana protein match is: Telomerase activating protein Est1 (TAIR:AT1G28260.2). & (reliability: 958.0) & (original description: no original description)


Gene families : OG_42_0003131 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0003131_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Picea release: MA_10435713g0020
Cluster HCCA clusters: Cluster_47

Target Alias Description ECC score Gene Family Method Actions
Bradi3g20200 No alias Telomerase activating protein Est1 0.06 Orthogroups_2024-Update
HORVU5Hr1G050800.5 No alias Nonsense-Mediated mRNA Decay protein *(SMG7) 0.02 Orthogroups_2024-Update
Pp1s311_73V6 No alias F7K24.150; expressed protein [Arabidopsis thaliana] 0.03 Orthogroups_2024-Update
Solyc10g080740 No alias Telomerase activating protein Est1 (AHRD V3.3 ***... 0.03 Orthogroups_2024-Update
Sopen10g031280 No alias Est1 DNA/RNA binding domain 0.04 Orthogroups_2024-Update

Type GO Term Name Evidence Source

No GO annotation available for this sequence

Type GO Term Name Evidence Source
BP GO:0000375 RNA splicing, via transesterification reactions IEP Predicted GO
BP GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile IEP Predicted GO
BP GO:0000398 mRNA splicing, via spliceosome IEP Predicted GO
MF GO:0003676 nucleic acid binding IEP Predicted GO
MF GO:0003712 transcription coregulator activity IEP Predicted GO
MF GO:0003723 RNA binding IEP Predicted GO
MF GO:0004402 histone acetyltransferase activity IEP Predicted GO
MF GO:0004652 polynucleotide adenylyltransferase activity IEP Predicted GO
MF GO:0004674 protein serine/threonine kinase activity IEP Predicted GO
MF GO:0005488 binding IEP Predicted GO
MF GO:0005515 protein binding IEP Predicted GO
CC GO:0005634 nucleus IEP Predicted GO
BP GO:0006139 nucleobase-containing compound metabolic process IEP Predicted GO
BP GO:0006325 chromatin organization IEP Predicted GO
BP GO:0006396 RNA processing IEP Predicted GO
BP GO:0006464 cellular protein modification process IEP Predicted GO
BP GO:0006473 protein acetylation IEP Predicted GO
BP GO:0006475 internal protein amino acid acetylation IEP Predicted GO
BP GO:0006479 protein methylation IEP Predicted GO
BP GO:0006725 cellular aromatic compound metabolic process IEP Predicted GO
BP GO:0006807 nitrogen compound metabolic process IEP Predicted GO
MF GO:0008080 N-acetyltransferase activity IEP Predicted GO
MF GO:0008170 N-methyltransferase activity IEP Predicted GO
BP GO:0008213 protein alkylation IEP Predicted GO
MF GO:0008234 cysteine-type peptidase activity IEP Predicted GO
MF GO:0008276 protein methyltransferase activity IEP Predicted GO
BP GO:0008380 RNA splicing IEP Predicted GO
BP GO:0009987 cellular process IEP Predicted GO
BP GO:0016070 RNA metabolic process IEP Predicted GO
MF GO:0016278 lysine N-methyltransferase activity IEP Predicted GO
MF GO:0016279 protein-lysine N-methyltransferase activity IEP Predicted GO
MF GO:0016407 acetyltransferase activity IEP Predicted GO
MF GO:0016410 N-acyltransferase activity IEP Predicted GO
BP GO:0016569 covalent chromatin modification IEP Predicted GO
BP GO:0016570 histone modification IEP Predicted GO
BP GO:0016571 histone methylation IEP Predicted GO
BP GO:0016573 histone acetylation IEP Predicted GO
BP GO:0016579 protein deubiquitination IEP Predicted GO
MF GO:0017069 snRNA binding IEP Predicted GO
MF GO:0017070 U6 snRNA binding IEP Predicted GO
BP GO:0018022 peptidyl-lysine methylation IEP Predicted GO
MF GO:0018024 histone-lysine N-methyltransferase activity IEP Predicted GO
BP GO:0018193 peptidyl-amino acid modification IEP Predicted GO
BP GO:0018205 peptidyl-lysine modification IEP Predicted GO
BP GO:0018393 internal peptidyl-lysine acetylation IEP Predicted GO
BP GO:0018394 peptidyl-lysine acetylation IEP Predicted GO
MF GO:0019783 ubiquitin-like protein-specific protease activity IEP Predicted GO
MF GO:0030623 U5 snRNA binding IEP Predicted GO
CC GO:0031011 Ino80 complex IEP Predicted GO
CC GO:0033202 DNA helicase complex IEP Predicted GO
MF GO:0034212 peptide N-acetyltransferase activity IEP Predicted GO
BP GO:0034968 histone lysine methylation IEP Predicted GO
BP GO:0036211 protein modification process IEP Predicted GO
MF GO:0036459 thiol-dependent ubiquitinyl hydrolase activity IEP Predicted GO
MF GO:0042054 histone methyltransferase activity IEP Predicted GO
BP GO:0043170 macromolecule metabolic process IEP Predicted GO
CC GO:0043227 membrane-bounded organelle IEP Predicted GO
CC GO:0043231 intracellular membrane-bounded organelle IEP Predicted GO
BP GO:0043412 macromolecule modification IEP Predicted GO
BP GO:0043543 protein acylation IEP Predicted GO
BP GO:0043631 RNA polyadenylation IEP Predicted GO
BP GO:0044237 cellular metabolic process IEP Predicted GO
BP GO:0044267 cellular protein metabolic process IEP Predicted GO
CC GO:0044428 nuclear part IEP Predicted GO
CC GO:0044454 nuclear chromosome part IEP Predicted GO
BP GO:0046483 heterocycle metabolic process IEP Predicted GO
BP GO:0048193 Golgi vesicle transport IEP Predicted GO
MF GO:0061733 peptide-lysine-N-acetyltransferase activity IEP Predicted GO
MF GO:0070566 adenylyltransferase activity IEP Predicted GO
CC GO:0070603 SWI/SNF superfamily-type complex IEP Predicted GO
BP GO:0070646 protein modification by small protein removal IEP Predicted GO
BP GO:0070647 protein modification by small protein conjugation or removal IEP Predicted GO
BP GO:0090304 nucleic acid metabolic process IEP Predicted GO
CC GO:0097346 INO80-type complex IEP Predicted GO
MF GO:0101005 ubiquitinyl hydrolase activity IEP Predicted GO
BP GO:1901360 organic cyclic compound metabolic process IEP Predicted GO
CC GO:1902494 catalytic complex IEP Predicted GO
CC GO:1904949 ATPase complex IEP Predicted GO
InterPro domains Description Start Stop
IPR018834 DNA/RNA-bd_Est1-type 249 596
IPR019458 EST1 112 236
No external refs found!