Description : (at5g04560 : 155.0) Encodes a DNA glycosylase DEMETER (DME). Responsible for endosperm maternal-allele-specific hypomethylation at the MEDEA (MEA) gene. DME can excise 5-methylcytosine in vitro and when expressed in E. coli. DME establishes MEA imprinting by removing 5-methylcytosine to activate the maternal allele.; DEMETER (DME); CONTAINS InterPro DOMAIN/s: DNA glycosylase (InterPro:IPR011257), Endonuclease III-like, iron-sulphur cluster loop motif (InterPro:IPR003651), HhH-GPD domain (InterPro:IPR003265); BEST Arabidopsis thaliana protein match is: demeter-like 1 (TAIR:AT2G36490.1); Has 3806 Blast hits to 3649 proteins in 1364 species: Archae - 237; Bacteria - 2338; Metazoa - 256; Fungi - 124; Plants - 347; Viruses - 0; Other Eukaryotes - 504 (source: NCBI BLink). & (reliability: 294.0) & (original description: no original description)
Gene families : OG_42_0001291 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0001291_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Picea release: MA_111413g0010 | |
Cluster | HCCA clusters: Cluster_108 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
Glyma.10G202150 | No alias | HhH-GPD base excision DNA repair family protein | 0.03 | Orthogroups_2024-Update | |
Kfl00179_0260 | kfl00179_0260_v1.1 | (at3g10010 : 280.0) Encodes a protein with DNA... | 0.01 | Orthogroups_2024-Update | |
Pp1s226_20V6 | No alias | dna glycosylase | 0.02 | Orthogroups_2024-Update | |
Seita.1G164500.1 | No alias | methylcytosine-specific DNA glycosylase *(ROS1) | 0.02 | Orthogroups_2024-Update |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No GO annotation available for this sequence |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
BP | GO:0000413 | protein peptidyl-prolyl isomerization | IEP | Predicted GO |
MF | GO:0003755 | peptidyl-prolyl cis-trans isomerase activity | IEP | Predicted GO |
MF | GO:0008270 | zinc ion binding | IEP | Predicted GO |
MF | GO:0016853 | isomerase activity | IEP | Predicted GO |
MF | GO:0016859 | cis-trans isomerase activity | IEP | Predicted GO |
BP | GO:0018193 | peptidyl-amino acid modification | IEP | Predicted GO |
BP | GO:0018208 | peptidyl-proline modification | IEP | Predicted GO |
MF | GO:0046914 | transition metal ion binding | IEP | Predicted GO |
No InterPro domains available for this sequence
No external refs found! |