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Description : (q8w013|comt1_catro : 214.0) Caffeic acid 3-O-methyltransferase (EC 2.1.1.68) (S-adenosysl-L-methionine:caffeic acid 3-O-methyltransferase) (COMT) (CAOMT) - Catharanthus roseus (Rosy periwinkle) (Madagascar periwinkle) & (at5g54160 : 210.0) A caffeic acid/5-hydroxyferulic acid O-methyltransferase. Interacts with 14-4-3 proteins in yeast 2 hybrid assay. AtOMT1 (At5g54160) encodes a flavonol 3Ã-O-methyltransferase that is highly active towards quercetin and myricetin. The substrate specificity identifies the enzyme as flavonol 3Ã-methyltransferase which replaces the former annotation of the gene to encode a caffeic acid/5-hydroxyferulic acid O-methyltransferase; O-methyltransferase 1 (OMT1); FUNCTIONS IN: myricetin 3'-O-methyltransferase activity, quercetin 3-O-methyltransferase activity, caffeate O-methyltransferase activity; INVOLVED IN: lignin biosynthetic process, flavonol biosynthetic process; LOCATED IN: cytosol, nucleus, plasma membrane, cytoplasm; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Winged helix-turn-helix transcription repressor DNA-binding (InterPro:IPR011991), Plant methyltransferase dimerisation (InterPro:IPR012967), O-methyltransferase, family 2 (InterPro:IPR001077), O-methyltransferase, COMT, eukaryota (InterPro:IPR016461); BEST Arabidopsis thaliana protein match is: O-methyltransferase family protein (TAIR:AT1G77520.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 420.0) & (original description: no original description)
Gene families : OG_42_0000016 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000016_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
| Type | Description | Actions |
|---|---|---|
| Neighborhood | Picea release: MA_392462g0010 | |
| Cluster | HCCA clusters: Cluster_103 |
| Target | Alias | Description | ECC score | Gene Family Method | Actions |
|---|---|---|---|---|---|
| Bradi2g50111 | No alias | O-methyltransferase family protein | 0.02 | Orthogroups_2024-Update | |
| Brara.B01423.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.03 | Orthogroups_2024-Update | |
| Brara.G02146.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.03 | Orthogroups_2024-Update | |
| Glyma.13G173300 | No alias | O-methyltransferase family protein | 0.03 | Orthogroups_2024-Update | |
| Glyma.14G201100 | No alias | O-methyltransferase family protein | 0.03 | Orthogroups_2024-Update | |
| LOC_Os08g06100 | No alias | O-methyltransferase, putative, expressed | 0.03 | Orthogroups_2024-Update | |
| LOC_Os11g12760 | No alias | O-methyltransferase, putative, expressed | 0.02 | Orthogroups_2024-Update | |
| PSME_00034122-RA | No alias | (at5g54160 : 196.0) A caffeic acid/5-hydroxyferulic acid... | 0.03 | Orthogroups_2024-Update | |
| Seita.6G174800.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.03 | Orthogroups_2024-Update | |
| Sobic.001G346800.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.02 | Orthogroups_2024-Update | |
| Sobic.004G128400.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.03 | Orthogroups_2024-Update | |
| Sobic.007G058600.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.05 | Orthogroups_2024-Update | |
| Sobic.007G059100.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.03 | Orthogroups_2024-Update | |
| Sobic.007G170500.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.04 | Orthogroups_2024-Update | |
| Sobic.010G230800.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.02 | Orthogroups_2024-Update | |
| Sobic.010G231000.2 | No alias | EC_2.1 transferase transferring one-carbon group | 0.02 | Orthogroups_2024-Update | |
| Solyc03g097700 | No alias | O-methyltransferase (AHRD V3.3 *** F6M2M1_VITPS) | 0.03 | Orthogroups_2024-Update | |
| Sopen01g053940 | No alias | O-methyltransferase | 0.02 | Orthogroups_2024-Update |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
| MF | GO:0008171 | O-methyltransferase activity | IEA | InterProScan predictions |
| MF | GO:0046983 | protein dimerization activity | IEA | InterProScan predictions |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
| MF | GO:0004144 | diacylglycerol O-acyltransferase activity | IEP | Predicted GO |
| BP | GO:0006457 | protein folding | IEP | Predicted GO |
| BP | GO:0006766 | vitamin metabolic process | IEP | Predicted GO |
| BP | GO:0006767 | water-soluble vitamin metabolic process | IEP | Predicted GO |
| BP | GO:0006771 | riboflavin metabolic process | IEP | Predicted GO |
| MF | GO:0008703 | 5-amino-6-(5-phosphoribosylamino)uracil reductase activity | IEP | Predicted GO |
| BP | GO:0009110 | vitamin biosynthetic process | IEP | Predicted GO |
| BP | GO:0009231 | riboflavin biosynthetic process | IEP | Predicted GO |
| MF | GO:0016411 | acylglycerol O-acyltransferase activity | IEP | Predicted GO |
| BP | GO:0042364 | water-soluble vitamin biosynthetic process | IEP | Predicted GO |
| BP | GO:0042726 | flavin-containing compound metabolic process | IEP | Predicted GO |
| BP | GO:0042727 | flavin-containing compound biosynthetic process | IEP | Predicted GO |
| CC | GO:0044451 | nucleoplasm part | IEP | Predicted GO |
| BP | GO:0045017 | glycerolipid biosynthetic process | IEP | Predicted GO |
| MF | GO:0051082 | unfolded protein binding | IEP | Predicted GO |
| CC | GO:0071821 | FANCM-MHF complex | IEP | Predicted GO |
| No external refs found! |