Description : (at1g63440 : 247.0) The Arabidopsis P-type ATPase HMA5 is involved in Cu detoxification. hma5 mutant plants exhibit Cu hypersensitivity, which is especially dramatic in roots where HMA5 is mostly expressed.; heavy metal atpase 5 (HMA5); FUNCTIONS IN: ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism; INVOLVED IN: detoxification of copper ion, response to copper ion; LOCATED IN: integral to membrane, membrane; EXPRESSED IN: 8 plant structures; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage, 4 anthesis, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Heavy metal transport/detoxification protein (InterPro:IPR006121), ATPase, P type, cation/copper-transporter (InterPro:IPR006403), ATPase, P-type, ATPase-associated domain (InterPro:IPR008250), Heavy-metal-associated, conserved site (InterPro:IPR017969), Haloacid dehalogenase-like hydrolase (InterPro:IPR005834), ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter (InterPro:IPR001757), ATPase, P-type, heavy metal translocating (InterPro:IPR006416), ATPase, P-type phosphorylation site (InterPro:IPR018303); BEST Arabidopsis thaliana protein match is: copper-exporting ATPase / responsive-to-antagonist 1 / copper-transporting ATPase (RAN1) (TAIR:AT5G44790.1); Has 47061 Blast hits to 34034 proteins in 3459 species: Archae - 1020; Bacteria - 31793; Metazoa - 4958; Fungi - 2589; Plants - 1873; Viruses - 3; Other Eukaryotes - 4825 (source: NCBI BLink). & (reliability: 494.0) & (original description: no original description)
Gene families : OG_42_0000805 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000805_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Picea release: MA_98746g0010 | |
Cluster | HCCA clusters: Cluster_146 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
A4A49_08243 | No alias | putative copper-transporting atpase hma5 | 0.03 | Orthogroups_2024-Update | |
Brara.J00792.1 | No alias | P1B-type heavy metal cation-transporting ATPase *(HMA) | 0.03 | Orthogroups_2024-Update | |
MA_253979g0010 | No alias | (at5g44790 : 162.0) ATP dependent copper transporter... | 0.04 | Orthogroups_2024-Update | |
MA_35653g0010 | No alias | (at5g44790 : 168.0) ATP dependent copper transporter... | 0.04 | Orthogroups_2024-Update | |
Potri.001G158900 | No alias | copper-exporting ATPase / responsive-to-antagonist 1 /... | 0.03 | Orthogroups_2024-Update | |
Seita.4G185100.1 | No alias | P1B-type heavy metal cation-transporting ATPase *(HMA) | 0.03 | Orthogroups_2024-Update |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No GO annotation available for this sequence |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0004356 | glutamate-ammonia ligase activity | IEP | Predicted GO |
CC | GO:0005787 | signal peptidase complex | IEP | Predicted GO |
BP | GO:0006082 | organic acid metabolic process | IEP | Predicted GO |
BP | GO:0006465 | signal peptide processing | IEP | Predicted GO |
BP | GO:0006541 | glutamine metabolic process | IEP | Predicted GO |
BP | GO:0006542 | glutamine biosynthetic process | IEP | Predicted GO |
BP | GO:0006650 | glycerophospholipid metabolic process | IEP | Predicted GO |
MF | GO:0008061 | chitin binding | IEP | Predicted GO |
BP | GO:0009064 | glutamine family amino acid metabolic process | IEP | Predicted GO |
BP | GO:0009084 | glutamine family amino acid biosynthetic process | IEP | Predicted GO |
MF | GO:0016211 | ammonia ligase activity | IEP | Predicted GO |
BP | GO:0016485 | protein processing | IEP | Predicted GO |
MF | GO:0016705 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | IEP | Predicted GO |
MF | GO:0016717 | oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water | IEP | Predicted GO |
MF | GO:0016879 | ligase activity, forming carbon-nitrogen bonds | IEP | Predicted GO |
MF | GO:0016880 | acid-ammonia (or amide) ligase activity | IEP | Predicted GO |
BP | GO:0019752 | carboxylic acid metabolic process | IEP | Predicted GO |
BP | GO:0030258 | lipid modification | IEP | Predicted GO |
BP | GO:0043436 | oxoacid metabolic process | IEP | Predicted GO |
BP | GO:0044255 | cellular lipid metabolic process | IEP | Predicted GO |
CC | GO:0044432 | endoplasmic reticulum part | IEP | Predicted GO |
MF | GO:0045300 | acyl-[acyl-carrier-protein] desaturase activity | IEP | Predicted GO |
BP | GO:0046488 | phosphatidylinositol metabolic process | IEP | Predicted GO |
BP | GO:0046834 | lipid phosphorylation | IEP | Predicted GO |
BP | GO:0046854 | phosphatidylinositol phosphorylation | IEP | Predicted GO |
BP | GO:0051604 | protein maturation | IEP | Predicted GO |
CC | GO:1905368 | peptidase complex | IEP | Predicted GO |
No InterPro domains available for this sequence
No external refs found! |