Description : (at3g06483 : 182.0) Pyruvate dehydrogenase kinase (PDK) specifically phosphorylates the E1α subunit of the pyruvate dehydrogenase complex (PDC) on a Ser residue using ATP as a phosphate donor. PDK is a unique type of protein kinase having a His-kinase-like sequence but Ser-kinase activity. Site-directed mutagenesis and structural analysis indicate that PDK belongs to the GHKL superfamily.; pyruvate dehydrogenase kinase (PDK); FUNCTIONS IN: ATP binding, pyruvate dehydrogenase (acetyl-transferring) kinase activity, histidine phosphotransfer kinase activity; INVOLVED IN: signal transduction, peptidyl-histidine phosphorylation, phosphorylation; LOCATED IN: mitochondrion; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Signal transduction histidine kinase, core (InterPro:IPR005467), Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, mitochondrial (InterPro:IPR018955), ATPase-like, ATP-binding domain (InterPro:IPR003594), Signal transduction histidine kinase-related protein, C-terminal (InterPro:IPR004358); Has 1925 Blast hits to 1799 proteins in 531 species: Archae - 0; Bacteria - 712; Metazoa - 467; Fungi - 468; Plants - 102; Viruses - 0; Other Eukaryotes - 176 (source: NCBI BLink). & (reliability: 364.0) & (original description: no original description)
Gene families : OG_42_0143829 (Orthogroups_2024-Update) Phylogenetic Tree(s): No tree available for this family
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Porphyridium release: evm.model.contig_2072.5 | |
Cluster | HCCA clusters: Cluster_46 |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No GO annotation available for this sequence |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
BP | GO:0000075 | cell cycle checkpoint | IEP | Predicted GO |
BP | GO:0000077 | DNA damage checkpoint | IEP | Predicted GO |
MF | GO:0003725 | double-stranded RNA binding | IEP | Predicted GO |
MF | GO:0003989 | acetyl-CoA carboxylase activity | IEP | Predicted GO |
MF | GO:0004109 | coproporphyrinogen oxidase activity | IEP | Predicted GO |
MF | GO:0004751 | ribose-5-phosphate isomerase activity | IEP | Predicted GO |
BP | GO:0006081 | cellular aldehyde metabolic process | IEP | Predicted GO |
BP | GO:0006298 | mismatch repair | IEP | Predicted GO |
BP | GO:0006631 | fatty acid metabolic process | IEP | Predicted GO |
BP | GO:0006633 | fatty acid biosynthetic process | IEP | Predicted GO |
BP | GO:0006778 | porphyrin-containing compound metabolic process | IEP | Predicted GO |
BP | GO:0006779 | porphyrin-containing compound biosynthetic process | IEP | Predicted GO |
BP | GO:0006950 | response to stress | IEP | Predicted GO |
BP | GO:0006974 | cellular response to DNA damage stimulus | IEP | Predicted GO |
BP | GO:0009052 | pentose-phosphate shunt, non-oxidative branch | IEP | Predicted GO |
CC | GO:0009521 | photosystem | IEP | Predicted GO |
CC | GO:0009523 | photosystem II | IEP | Predicted GO |
CC | GO:0009654 | photosystem II oxygen evolving complex | IEP | Predicted GO |
MF | GO:0016421 | CoA carboxylase activity | IEP | Predicted GO |
MF | GO:0016634 | oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor | IEP | Predicted GO |
MF | GO:0016851 | magnesium chelatase activity | IEP | Predicted GO |
MF | GO:0016860 | intramolecular oxidoreductase activity | IEP | Predicted GO |
MF | GO:0016861 | intramolecular oxidoreductase activity, interconverting aldoses and ketoses | IEP | Predicted GO |
MF | GO:0016874 | ligase activity | IEP | Predicted GO |
MF | GO:0016885 | ligase activity, forming carbon-carbon bonds | IEP | Predicted GO |
BP | GO:0019682 | glyceraldehyde-3-phosphate metabolic process | IEP | Predicted GO |
CC | GO:0019898 | extrinsic component of membrane | IEP | Predicted GO |
CC | GO:0030896 | checkpoint clamp complex | IEP | Predicted GO |
MF | GO:0030983 | mismatched DNA binding | IEP | Predicted GO |
BP | GO:0031570 | DNA integrity checkpoint | IEP | Predicted GO |
BP | GO:0033554 | cellular response to stress | IEP | Predicted GO |
CC | GO:0044454 | nuclear chromosome part | IEP | Predicted GO |
BP | GO:0045786 | negative regulation of cell cycle | IEP | Predicted GO |
BP | GO:0048523 | negative regulation of cellular process | IEP | Predicted GO |
BP | GO:0050896 | response to stimulus | IEP | Predicted GO |
MF | GO:0051002 | ligase activity, forming nitrogen-metal bonds | IEP | Predicted GO |
MF | GO:0051003 | ligase activity, forming nitrogen-metal bonds, forming coordination complexes | IEP | Predicted GO |
BP | GO:0051716 | cellular response to stimulus | IEP | Predicted GO |
CC | GO:1990204 | oxidoreductase complex | IEP | Predicted GO |
No external refs found! |