PSME_00000251-RA

Description : (at3g13090 : 785.0) member of MRP subfamily; multidrug resistance-associated protein 8 (MRP8); FUNCTIONS IN: ATPase activity, coupled to transmembrane movement of substances; INVOLVED IN: transport, transmembrane transport; LOCATED IN: plasma membrane; EXPRESSED IN: 10 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ABC transporter-like (InterPro:IPR003439), ABC transporter, transmembrane domain, type 1 (InterPro:IPR011527), ABC transporter integral membrane type 1 (InterPro:IPR017940), ABC transporter, transmembrane domain (InterPro:IPR001140), ABC transporter, conserved site (InterPro:IPR017871); BEST Arabidopsis thaliana protein match is: multidrug resistance-associated protein 7 (TAIR:AT3G13100.1); Has 618731 Blast hits to 341231 proteins in 4024 species: Archae - 11229; Bacteria - 503340; Metazoa - 11410; Fungi - 6818; Plants - 5765; Viruses - 13; Other Eukaryotes - 80156 (source: NCBI BLink). & (q6yuu5|mdr_orysa : 123.0) Putative multidrug resistance protein (P-glycoprotein) - Oryza sativa (Rice) & (reliability: 1570.0) & (original description: no original description)

Gene families : OG_42_0000076 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000076_tree

Sequence : coding (download), protein (download)

Attention: This gene has low abundance.

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pseudotsuga release: PSME_00000251-RA
Cluster	HCCA clusters: Cluster_150

Target	Alias	Description	ECC score	Gene Family Method
A4A49_01671	No alias	abc transporter c family member 9	0.02	Orthogroups_2024-Update
A4A49_10152	No alias	abc transporter c family member 14	0.02	Orthogroups_2024-Update
A4A49_42365	No alias	abc transporter c family member 14	0.02	Orthogroups_2024-Update
At2g34660	No alias	ABC transporter C family member 2...	0.04	Orthogroups_2024-Update
At3g21250	No alias	Multidrug resistance-associated protein 6...	0.04	Orthogroups_2024-Update
At3g59140	No alias	ABC transporter C family member 10...	0.03	Orthogroups_2024-Update
Brara.A02781.1	No alias	subfamily ABCC transporter	0.03	Orthogroups_2024-Update
Brara.G01873.1	No alias	subfamily ABCC transporter	0.04	Orthogroups_2024-Update
Brara.I04331.1	No alias	subfamily ABCC transporter	0.02	Orthogroups_2024-Update
Cre02.g103250	No alias	multidrug resistance-associated protein 2	0.02	Orthogroups_2024-Update
Cre08.g369720	No alias	multidrug resistance-associated protein 2	0.01	Orthogroups_2024-Update
Glyma.05G145000	No alias	multidrug resistance-associated protein 3	0.03	Orthogroups_2024-Update
Glyma.07G121900	No alias	multidrug resistance-associated protein 9	0.04	Orthogroups_2024-Update
Glyma.08G190700	No alias	multidrug resistance-associated protein 6	0.03	Orthogroups_2024-Update
Glyma.10G019000	No alias	multidrug resistance-associated protein 4	0.03	Orthogroups_2024-Update
Glyma.13G127500	No alias	multidrug resistance-associated protein 5	0.03	Orthogroups_2024-Update
Glyma.19G169000	No alias	multidrug resistance-associated protein 5	0.03	Orthogroups_2024-Update
LOC_Os01g07870	No alias	ABC transporter family protein, putative, expressed	0.03	Orthogroups_2024-Update
LOC_Os03g04920	No alias	multidrug resistance-associated protein, putative, expressed	0.02	Orthogroups_2024-Update
LOC_Os06g08560	No alias	multidrug resistance-associated protein 11, putative, expressed	0.03	Orthogroups_2024-Update
Mp5g02230.1	No alias	subfamily ABCC transporter	0.02	Orthogroups_2024-Update
Mp5g13190.1	No alias	subfamily ABCC transporter	0.02	Orthogroups_2024-Update
Mp7g13400.1	No alias	subfamily ABCC transporter	0.02	Orthogroups_2024-Update
Potri.003G197200	No alias	multidrug resistance-associated protein 3	0.04	Orthogroups_2024-Update
Potri.004G034700	No alias	multidrug resistance-associated protein 2	0.02	Orthogroups_2024-Update
Potri.014G180100	No alias	multidrug resistance-associated protein 9	0.03	Orthogroups_2024-Update
Pp1s224_120V6	No alias	multidrug resistance protein abc transporter family	0.02	Orthogroups_2024-Update
Seita.7G216700.1	No alias	subfamily ABCC transporter	0.03	Orthogroups_2024-Update
Sopen08g002840	No alias	ABC transporter transmembrane region	0.02	Orthogroups_2024-Update
Sopen12g023190	No alias	ABC transporter	0.03	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0005215	transporter activity	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	InterProScan predictions
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0006810	transport	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
MF	GO:0015399	primary active transmembrane transporter activity	None	Extended
MF	GO:0015405	P-P-bond-hydrolysis-driven transmembrane transporter activity	None	Extended
CC	GO:0016021	integral component of membrane	IEA	InterProScan predictions
MF	GO:0016462	pyrophosphatase activity	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	None	Extended
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	None	Extended
MF	GO:0016887	ATPase activity	IEA	InterProScan predictions
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0017111	nucleoside-triphosphatase activity	None	Extended
MF	GO:0022804	active transmembrane transporter activity	None	Extended
MF	GO:0022857	transmembrane transporter activity	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
CC	GO:0031224	intrinsic component of membrane	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0042623	ATPase activity, coupled	None	Extended
MF	GO:0042626	ATPase activity, coupled to transmembrane movement of substances	IEA	InterProScan predictions
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
MF	GO:0043492	ATPase activity, coupled to movement of substances	None	Extended
CC	GO:0044425	membrane part	None	Extended
BP	GO:0051179	localization	None	Extended
BP	GO:0051234	establishment of localization	None	Extended
BP	GO:0055085	transmembrane transport	IEA	InterProScan predictions
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0003849	3-deoxy-7-phosphoheptulonate synthase activity	IEP	Predicted GO
MF	GO:0004180	carboxypeptidase activity	IEP	Predicted GO
MF	GO:0004185	serine-type carboxypeptidase activity	IEP	Predicted GO
MF	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity	IEP	Predicted GO
MF	GO:0005086	ARF guanyl-nucleotide exchange factor activity	IEP	Predicted GO
BP	GO:0006072	glycerol-3-phosphate metabolic process	IEP	Predicted GO
BP	GO:0006605	protein targeting	IEP	Predicted GO
BP	GO:0006612	protein targeting to membrane	IEP	Predicted GO
BP	GO:0006613	cotranslational protein targeting to membrane	IEP	Predicted GO
BP	GO:0006614	SRP-dependent cotranslational protein targeting to membrane	IEP	Predicted GO
BP	GO:0006766	vitamin metabolic process	IEP	Predicted GO
BP	GO:0006767	water-soluble vitamin metabolic process	IEP	Predicted GO
BP	GO:0006772	thiamine metabolic process	IEP	Predicted GO
BP	GO:0006790	sulfur compound metabolic process	IEP	Predicted GO
MF	GO:0008236	serine-type peptidase activity	IEP	Predicted GO
MF	GO:0008312	7S RNA binding	IEP	Predicted GO
BP	GO:0008652	cellular amino acid biosynthetic process	IEP	Predicted GO
BP	GO:0009110	vitamin biosynthetic process	IEP	Predicted GO
BP	GO:0009228	thiamine biosynthetic process	IEP	Predicted GO
MF	GO:0009916	alternative oxidase activity	IEP	Predicted GO
BP	GO:0009966	regulation of signal transduction	IEP	Predicted GO
BP	GO:0010646	regulation of cell communication	IEP	Predicted GO
MF	GO:0015035	protein disulfide oxidoreductase activity	IEP	Predicted GO
MF	GO:0015036	disulfide oxidoreductase activity	IEP	Predicted GO
MF	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	IEP	Predicted GO
MF	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	IEP	Predicted GO
MF	GO:0016679	oxidoreductase activity, acting on diphenols and related substances as donors	IEP	Predicted GO
MF	GO:0016682	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor	IEP	Predicted GO
MF	GO:0017171	serine hydrolase activity	IEP	Predicted GO
BP	GO:0022613	ribonucleoprotein complex biogenesis	IEP	Predicted GO
BP	GO:0023051	regulation of signaling	IEP	Predicted GO
CC	GO:0030684	preribosome	IEP	Predicted GO
CC	GO:0030688	preribosome, small subunit precursor	IEP	Predicted GO
BP	GO:0032012	regulation of ARF protein signal transduction	IEP	Predicted GO
BP	GO:0042254	ribosome biogenesis	IEP	Predicted GO
BP	GO:0042364	water-soluble vitamin biosynthetic process	IEP	Predicted GO
BP	GO:0042723	thiamine-containing compound metabolic process	IEP	Predicted GO
BP	GO:0042724	thiamine-containing compound biosynthetic process	IEP	Predicted GO
BP	GO:0044085	cellular component biogenesis	IEP	Predicted GO
BP	GO:0044272	sulfur compound biosynthetic process	IEP	Predicted GO
BP	GO:0044283	small molecule biosynthetic process	IEP	Predicted GO
BP	GO:0045047	protein targeting to ER	IEP	Predicted GO
BP	GO:0046168	glycerol-3-phosphate catabolic process	IEP	Predicted GO
BP	GO:0046578	regulation of Ras protein signal transduction	IEP	Predicted GO
MF	GO:0048037	cofactor binding	IEP	Predicted GO
CC	GO:0048500	signal recognition particle	IEP	Predicted GO
BP	GO:0048583	regulation of response to stimulus	IEP	Predicted GO
BP	GO:0051056	regulation of small GTPase mediated signal transduction	IEP	Predicted GO
MF	GO:0051287	NAD binding	IEP	Predicted GO
BP	GO:0052646	alditol phosphate metabolic process	IEP	Predicted GO
BP	GO:0070972	protein localization to endoplasmic reticulum	IEP	Predicted GO
BP	GO:0072527	pyrimidine-containing compound metabolic process	IEP	Predicted GO
BP	GO:0072528	pyrimidine-containing compound biosynthetic process	IEP	Predicted GO
BP	GO:0072599	establishment of protein localization to endoplasmic reticulum	IEP	Predicted GO
BP	GO:0072657	protein localization to membrane	IEP	Predicted GO
BP	GO:0090150	establishment of protein localization to membrane	IEP	Predicted GO
BP	GO:1902531	regulation of intracellular signal transduction	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR003439	ABC_transporter-like	1130	1170
IPR011527	ABC1_TM_dom	297	564
IPR011527	ABC1_TM_dom	846	1032
IPR003439	ABC_transporter-like	629	763

External Links

No external refs found!

PSME_00000251-RA

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation