Description : (at3g21640 : 302.0) encodes a 42 kDa FK506-binding protein (AtFKBP42) that possesses similarity to multidomain peptidyl-prolyl cis/trans isomerases (PPIases, EC 5.2.1.8), which are known to be components of mammalian steroid hormone receptor complexes. The protein appears to be localized to the plasma membrane by electron microscopy and binds to HSP90.1 and calmodulin in vitro. It also aggregates citrate synthase in vitro but does NOT show PPIase activity in vivo. Mutants are reduced in size and exhibit disoriented growth in all organs.; TWISTED DWARF 1 (TWD1); CONTAINS InterPro DOMAIN/s: Tetratricopeptide-like helical (InterPro:IPR011990), Tetratricopeptide TPR2 (InterPro:IPR013105), Tetratricopeptide repeat-containing (InterPro:IPR013026), Tetratricopeptide repeat (InterPro:IPR019734), Peptidyl-prolyl cis-trans isomerase, FKBP-type (InterPro:IPR001179); BEST Arabidopsis thaliana protein match is: rotamase FKBP 1 (TAIR:AT3G25230.2); Has 6043 Blast hits to 5631 proteins in 871 species: Archae - 12; Bacteria - 1331; Metazoa - 2461; Fungi - 414; Plants - 774; Viruses - 0; Other Eukaryotes - 1051 (source: NCBI BLink). & (q43207|fkb70_wheat : 86.3) 70 kDa peptidyl-prolyl isomerase (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) - Triticum aestivum (Wheat) & (reliability: 604.0) & (original description: no original description)
Gene families : OG_42_0005483 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0005483_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Pseudotsuga release: PSME_00008309-RA | |
Cluster | HCCA clusters: Cluster_16 |
Type | GO Term | Name | Evidence | Source |
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MF | GO:0005515 | protein binding | IEA | InterProScan predictions |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0003916 | DNA topoisomerase activity | IEP | Predicted GO |
MF | GO:0003918 | DNA topoisomerase type II (ATP-hydrolyzing) activity | IEP | Predicted GO |
MF | GO:0004298 | threonine-type endopeptidase activity | IEP | Predicted GO |
CC | GO:0005730 | nucleolus | IEP | Predicted GO |
CC | GO:0005839 | proteasome core complex | IEP | Predicted GO |
BP | GO:0006265 | DNA topological change | IEP | Predicted GO |
BP | GO:0006418 | tRNA aminoacylation for protein translation | IEP | Predicted GO |
BP | GO:0006488 | dolichol-linked oligosaccharide biosynthetic process | IEP | Predicted GO |
BP | GO:0006490 | oligosaccharide-lipid intermediate biosynthetic process | IEP | Predicted GO |
BP | GO:0006508 | proteolysis | IEP | Predicted GO |
MF | GO:0008094 | DNA-dependent ATPase activity | IEP | Predicted GO |
MF | GO:0008233 | peptidase activity | IEP | Predicted GO |
BP | GO:0016579 | protein deubiquitination | IEP | Predicted GO |
MF | GO:0019783 | ubiquitin-like protein-specific protease activity | IEP | Predicted GO |
MF | GO:0036459 | thiol-dependent ubiquitinyl hydrolase activity | IEP | Predicted GO |
BP | GO:0051603 | proteolysis involved in cellular protein catabolic process | IEP | Predicted GO |
MF | GO:0061505 | DNA topoisomerase II activity | IEP | Predicted GO |
MF | GO:0070003 | threonine-type peptidase activity | IEP | Predicted GO |
MF | GO:0070011 | peptidase activity, acting on L-amino acid peptides | IEP | Predicted GO |
BP | GO:0070646 | protein modification by small protein removal | IEP | Predicted GO |
BP | GO:0071103 | DNA conformation change | IEP | Predicted GO |
MF | GO:0101005 | ubiquitinyl hydrolase activity | IEP | Predicted GO |
MF | GO:0140097 | catalytic activity, acting on DNA | IEP | Predicted GO |
No external refs found! |