PSME_00008309-RA


Description : (at3g21640 : 302.0) encodes a 42 kDa FK506-binding protein (AtFKBP42) that possesses similarity to multidomain peptidyl-prolyl cis/trans isomerases (PPIases, EC 5.2.1.8), which are known to be components of mammalian steroid hormone receptor complexes. The protein appears to be localized to the plasma membrane by electron microscopy and binds to HSP90.1 and calmodulin in vitro. It also aggregates citrate synthase in vitro but does NOT show PPIase activity in vivo. Mutants are reduced in size and exhibit disoriented growth in all organs.; TWISTED DWARF 1 (TWD1); CONTAINS InterPro DOMAIN/s: Tetratricopeptide-like helical (InterPro:IPR011990), Tetratricopeptide TPR2 (InterPro:IPR013105), Tetratricopeptide repeat-containing (InterPro:IPR013026), Tetratricopeptide repeat (InterPro:IPR019734), Peptidyl-prolyl cis-trans isomerase, FKBP-type (InterPro:IPR001179); BEST Arabidopsis thaliana protein match is: rotamase FKBP 1 (TAIR:AT3G25230.2); Has 6043 Blast hits to 5631 proteins in 871 species: Archae - 12; Bacteria - 1331; Metazoa - 2461; Fungi - 414; Plants - 774; Viruses - 0; Other Eukaryotes - 1051 (source: NCBI BLink). & (q43207|fkb70_wheat : 86.3) 70 kDa peptidyl-prolyl isomerase (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) - Triticum aestivum (Wheat) & (reliability: 604.0) & (original description: no original description)


Gene families : OG_42_0005483 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0005483_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00008309-RA
Cluster HCCA clusters: Cluster_16


Type GO Term Name Evidence Source
MF GO:0005515 protein binding IEA InterProScan predictions
Type GO Term Name Evidence Source
MF GO:0003916 DNA topoisomerase activity IEP Predicted GO
MF GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity IEP Predicted GO
MF GO:0004298 threonine-type endopeptidase activity IEP Predicted GO
CC GO:0005730 nucleolus IEP Predicted GO
CC GO:0005839 proteasome core complex IEP Predicted GO
BP GO:0006265 DNA topological change IEP Predicted GO
BP GO:0006418 tRNA aminoacylation for protein translation IEP Predicted GO
BP GO:0006488 dolichol-linked oligosaccharide biosynthetic process IEP Predicted GO
BP GO:0006490 oligosaccharide-lipid intermediate biosynthetic process IEP Predicted GO
BP GO:0006508 proteolysis IEP Predicted GO
MF GO:0008094 DNA-dependent ATPase activity IEP Predicted GO
MF GO:0008233 peptidase activity IEP Predicted GO
BP GO:0016579 protein deubiquitination IEP Predicted GO
MF GO:0019783 ubiquitin-like protein-specific protease activity IEP Predicted GO
MF GO:0036459 thiol-dependent ubiquitinyl hydrolase activity IEP Predicted GO
BP GO:0051603 proteolysis involved in cellular protein catabolic process IEP Predicted GO
MF GO:0061505 DNA topoisomerase II activity IEP Predicted GO
MF GO:0070003 threonine-type peptidase activity IEP Predicted GO
MF GO:0070011 peptidase activity, acting on L-amino acid peptides IEP Predicted GO
BP GO:0070646 protein modification by small protein removal IEP Predicted GO
BP GO:0071103 DNA conformation change IEP Predicted GO
MF GO:0101005 ubiquitinyl hydrolase activity IEP Predicted GO
MF GO:0140097 catalytic activity, acting on DNA IEP Predicted GO
InterPro domains Description Start Stop
IPR019734 TPR_repeat 126 152
IPR001179 PPIase_FKBP_dom 7 57
No external refs found!