PSME_00012623-RA


Description : (q8w013|comt1_catro : 272.0) Caffeic acid 3-O-methyltransferase (EC 2.1.1.68) (S-adenosysl-L-methionine:caffeic acid 3-O-methyltransferase) (COMT) (CAOMT) - Catharanthus roseus (Rosy periwinkle) (Madagascar periwinkle) & (at5g54160 : 261.0) A caffeic acid/5-hydroxyferulic acid O-methyltransferase. Interacts with 14-4-3 proteins in yeast 2 hybrid assay. AtOMT1 (At5g54160) encodes a flavonol 3í-O-methyltransferase that is highly active towards quercetin and myricetin. The substrate specificity identifies the enzyme as flavonol 3í-methyltransferase which replaces the former annotation of the gene to encode a caffeic acid/5-hydroxyferulic acid O-methyltransferase; O-methyltransferase 1 (OMT1); FUNCTIONS IN: myricetin 3'-O-methyltransferase activity, quercetin 3-O-methyltransferase activity, caffeate O-methyltransferase activity; INVOLVED IN: lignin biosynthetic process, flavonol biosynthetic process; LOCATED IN: cytosol, nucleus, plasma membrane, cytoplasm; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Winged helix-turn-helix transcription repressor DNA-binding (InterPro:IPR011991), Plant methyltransferase dimerisation (InterPro:IPR012967), O-methyltransferase, family 2 (InterPro:IPR001077), O-methyltransferase, COMT, eukaryota (InterPro:IPR016461); BEST Arabidopsis thaliana protein match is: O-methyltransferase family protein (TAIR:AT1G77520.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 490.0) & (original description: no original description)


Gene families : OG_42_0000016 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000016_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00012623-RA
Cluster HCCA clusters: Cluster_172

Target Alias Description ECC score Gene Family Method Actions
412283 No alias O-methyltransferase family protein 0.02 Orthogroups_2024-Update
At1g76790 No alias Indole glucosinolate O-methyltransferase 5... 0.03 Orthogroups_2024-Update
GRMZM2G140996 No alias O-methyltransferase family protein 0.03 Orthogroups_2024-Update
Glyma.09G281900 No alias O-methyltransferase 1 0.03 Orthogroups_2024-Update
HORVU6Hr1G092780.2 No alias EC_2.1 transferase transferring one-carbon group 0.04 Orthogroups_2024-Update
HORVU7Hr1G018880.1 No alias EC_2.1 transferase transferring one-carbon group 0.02 Orthogroups_2024-Update
LOC_Os11g20160 No alias O-methyltransferase, putative, expressed 0.02 Orthogroups_2024-Update
MA_1665780g0010 No alias no hits & (original description: no original description) 0.03 Orthogroups_2024-Update
MA_5226589g0010 No alias no hits & (original description: no original description) 0.03 Orthogroups_2024-Update
MA_8664817g0010 No alias no hits & (original description: no original description) 0.04 Orthogroups_2024-Update
MA_9153751g0010 No alias (q8w013|comt1_catro : 164.0) Caffeic acid... 0.03 Orthogroups_2024-Update
PSME_00009782-RA No alias (q9fqy8|comt1_capan : 433.0) Caffeic acid... 0.04 Orthogroups_2024-Update
PSME_00021108-RA No alias (p28002|comt1_medsa : 130.0) Caffeic acid... 0.04 Orthogroups_2024-Update
Potri.012G006400 No alias O-methyltransferase 1 0.04 Orthogroups_2024-Update
Sobic.009G197000.1 No alias EC_2.1 transferase transferring one-carbon group 0.03 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0008171 O-methyltransferase activity IEA InterProScan predictions
MF GO:0046983 protein dimerization activity IEA InterProScan predictions
Type GO Term Name Evidence Source
BP GO:0000096 sulfur amino acid metabolic process IEP Predicted GO
BP GO:0000097 sulfur amino acid biosynthetic process IEP Predicted GO
CC GO:0000123 histone acetyltransferase complex IEP Predicted GO
CC GO:0000124 SAGA complex IEP Predicted GO
MF GO:0003712 transcription coregulator activity IEP Predicted GO
MF GO:0003713 transcription coactivator activity IEP Predicted GO
MF GO:0004126 cytidine deaminase activity IEP Predicted GO
MF GO:0004527 exonuclease activity IEP Predicted GO
MF GO:0005516 calmodulin binding IEP Predicted GO
CC GO:0005643 nuclear pore IEP Predicted GO
BP GO:0006213 pyrimidine nucleoside metabolic process IEP Predicted GO
BP GO:0006216 cytidine catabolic process IEP Predicted GO
BP GO:0006405 RNA export from nucleus IEP Predicted GO
BP GO:0006406 mRNA export from nucleus IEP Predicted GO
BP GO:0006534 cysteine metabolic process IEP Predicted GO
BP GO:0006535 cysteine biosynthetic process from serine IEP Predicted GO
BP GO:0006563 L-serine metabolic process IEP Predicted GO
BP GO:0006790 sulfur compound metabolic process IEP Predicted GO
BP GO:0006811 ion transport IEP Predicted GO
BP GO:0006812 cation transport IEP Predicted GO
BP GO:0008037 cell recognition IEP Predicted GO
MF GO:0008270 zinc ion binding IEP Predicted GO
MF GO:0008324 cation transmembrane transporter activity IEP Predicted GO
MF GO:0008519 ammonium transmembrane transporter activity IEP Predicted GO
MF GO:0009001 serine O-acetyltransferase activity IEP Predicted GO
BP GO:0009069 serine family amino acid metabolic process IEP Predicted GO
BP GO:0009070 serine family amino acid biosynthetic process IEP Predicted GO
BP GO:0009119 ribonucleoside metabolic process IEP Predicted GO
BP GO:0009164 nucleoside catabolic process IEP Predicted GO
BP GO:0009891 positive regulation of biosynthetic process IEP Predicted GO
BP GO:0009893 positive regulation of metabolic process IEP Predicted GO
BP GO:0009972 cytidine deamination IEP Predicted GO
BP GO:0010557 positive regulation of macromolecule biosynthetic process IEP Predicted GO
BP GO:0010604 positive regulation of macromolecule metabolic process IEP Predicted GO
BP GO:0010628 positive regulation of gene expression IEP Predicted GO
MF GO:0015075 ion transmembrane transporter activity IEP Predicted GO
BP GO:0015696 ammonium transport IEP Predicted GO
BP GO:0015931 nucleobase-containing compound transport IEP Predicted GO
BP GO:0015985 energy coupled proton transport, down electrochemical gradient IEP Predicted GO
BP GO:0015986 ATP synthesis coupled proton transport IEP Predicted GO
BP GO:0016226 iron-sulfur cluster assembly IEP Predicted GO
MF GO:0016407 acetyltransferase activity IEP Predicted GO
MF GO:0016412 serine O-acyltransferase activity IEP Predicted GO
MF GO:0016413 O-acetyltransferase activity IEP Predicted GO
MF GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds IEP Predicted GO
MF GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines IEP Predicted GO
MF GO:0019239 deaminase activity IEP Predicted GO
BP GO:0019344 cysteine biosynthetic process IEP Predicted GO
BP GO:0022414 reproductive process IEP Predicted GO
BP GO:0031163 metallo-sulfur cluster assembly IEP Predicted GO
CC GO:0031248 protein acetyltransferase complex IEP Predicted GO
BP GO:0031325 positive regulation of cellular metabolic process IEP Predicted GO
BP GO:0031328 positive regulation of cellular biosynthetic process IEP Predicted GO
CC GO:0033177 proton-transporting two-sector ATPase complex, proton-transporting domain IEP Predicted GO
BP GO:0034656 nucleobase-containing small molecule catabolic process IEP Predicted GO
BP GO:0042454 ribonucleoside catabolic process IEP Predicted GO
BP GO:0044281 small molecule metabolic process IEP Predicted GO
BP GO:0044282 small molecule catabolic process IEP Predicted GO
CC GO:0044451 nucleoplasm part IEP Predicted GO
CC GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o) IEP Predicted GO
BP GO:0045893 positive regulation of transcription, DNA-templated IEP Predicted GO
BP GO:0045935 positive regulation of nucleobase-containing compound metabolic process IEP Predicted GO
BP GO:0046087 cytidine metabolic process IEP Predicted GO
BP GO:0046131 pyrimidine ribonucleoside metabolic process IEP Predicted GO
BP GO:0046133 pyrimidine ribonucleoside catabolic process IEP Predicted GO
BP GO:0046135 pyrimidine nucleoside catabolic process IEP Predicted GO
BP GO:0048518 positive regulation of biological process IEP Predicted GO
BP GO:0048522 positive regulation of cellular process IEP Predicted GO
BP GO:0048544 recognition of pollen IEP Predicted GO
BP GO:0050657 nucleic acid transport IEP Predicted GO
BP GO:0050658 RNA transport IEP Predicted GO
BP GO:0051028 mRNA transport IEP Predicted GO
BP GO:0051168 nuclear export IEP Predicted GO
BP GO:0051173 positive regulation of nitrogen compound metabolic process IEP Predicted GO
BP GO:0051236 establishment of RNA localization IEP Predicted GO
BP GO:0051254 positive regulation of RNA metabolic process IEP Predicted GO
BP GO:0055086 nucleobase-containing small molecule metabolic process IEP Predicted GO
CC GO:0070461 SAGA-type complex IEP Predicted GO
BP GO:0072527 pyrimidine-containing compound metabolic process IEP Predicted GO
BP GO:0072529 pyrimidine-containing compound catabolic process IEP Predicted GO
BP GO:1901135 carbohydrate derivative metabolic process IEP Predicted GO
BP GO:1901564 organonitrogen compound metabolic process IEP Predicted GO
BP GO:1901658 glycosyl compound catabolic process IEP Predicted GO
CC GO:1902493 acetyltransferase complex IEP Predicted GO
BP GO:1902680 positive regulation of RNA biosynthetic process IEP Predicted GO
BP GO:1903508 positive regulation of nucleic acid-templated transcription IEP Predicted GO
CC GO:1905368 peptidase complex IEP Predicted GO
InterPro domains Description Start Stop
IPR001077 O_MeTrfase_2 143 352
IPR012967 Plant_MeTrfase_dimerisation 37 87
No external refs found!