Description : (at1g15750 : 556.0) Encodes a protein with several WD40 repeats at the C-terminus and predicted protein-protein interaction domains at the N-terminus. Together with the TOPLESS-RELATED PROTEINS (TPRs), it is thought to be involved in transcriptional repression of root-promoting genes in the top help of the embryo during the transition stage of embryogenesis. The ability of IAA12 to repress transcription is diminished in a tpl-1 mutant background.; TOPLESS (TPL); FUNCTIONS IN: protein binding, transcription repressor activity, protein homodimerization activity; INVOLVED IN: xylem and phloem pattern formation, response to auxin stimulus, primary shoot apical meristem specification, jasmonic acid mediated signaling pathway; LOCATED IN: cytosol, nucleus; EXPRESSED IN: 27 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: WD40 repeat 2 (InterPro:IPR019782), WD40 repeat, conserved site (InterPro:IPR019775), WD40 repeat (InterPro:IPR001680), CTLH, C-terminal LisH motif (InterPro:IPR006595), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), LisH dimerisation motif (InterPro:IPR006594), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: TOPLESS-related 1 (TAIR:AT1G80490.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). & (reliability: 1112.0) & (original description: no original description)
Gene families : OG_42_0000373 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000373_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Pseudotsuga release: PSME_00014296-RA | |
Cluster | HCCA clusters: Cluster_249 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
Bradi1g67800 | No alias | TOPLESS-related 1 | 0.04 | Orthogroups_2024-Update | |
Bradi2g09080 | No alias | TOPLESS-related 2 | 0.03 | Orthogroups_2024-Update | |
Glyma.08G214600 | No alias | Transducin family protein / WD-40 repeat family protein | 0.02 | Orthogroups_2024-Update | |
Glyma.10G150000 | No alias | TOPLESS-related 3 | 0.03 | Orthogroups_2024-Update | |
Glyma.13G367300 | No alias | TOPLESS-related 1 | 0.03 | Orthogroups_2024-Update | |
Glyma.15G006100 | No alias | TOPLESS-related 1 | 0.03 | Orthogroups_2024-Update | |
Glyma.17G112500 | No alias | WUS-interacting protein 2 | 0.03 | Orthogroups_2024-Update | |
HORVU6Hr1G036010.9 | No alias | Unknown function | 0.04 | Orthogroups_2024-Update | |
Kfl00881_0020 | kfl00881_0020_v1.1 | (at1g15750 : 1113.0) Encodes a protein with several WD40... | 0.02 | Orthogroups_2024-Update | |
MA_10430083g0010 | No alias | (at1g15750 : 1644.0) Encodes a protein with several WD40... | 0.05 | Orthogroups_2024-Update | |
MA_10436445g0020 | No alias | (at1g15750 : 1515.0) Encodes a protein with several WD40... | 0.05 | Orthogroups_2024-Update | |
MA_16979g0020 | No alias | (at1g15750 : 344.0) Encodes a protein with several WD40... | 0.03 | Orthogroups_2024-Update | |
Mp7g17410.1 | No alias | transcriptional repressor (TPL). transcriptional... | 0.02 | Orthogroups_2024-Update | |
Seita.9G466100.1 | No alias | auxin signalling transcriptional co-repressor *(TPL/TPR)... | 0.02 | Orthogroups_2024-Update | |
Sobic.007G051700.1 | No alias | auxin signalling transcriptional co-repressor *(TPL/TPR)... | 0.02 | Orthogroups_2024-Update |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No GO annotation available for this sequence |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0003682 | chromatin binding | IEP | Predicted GO |
MF | GO:0003712 | transcription coregulator activity | IEP | Predicted GO |
MF | GO:0003714 | transcription corepressor activity | IEP | Predicted GO |
MF | GO:0005085 | guanyl-nucleotide exchange factor activity | IEP | Predicted GO |
MF | GO:0005086 | ARF guanyl-nucleotide exchange factor activity | IEP | Predicted GO |
MF | GO:0005534 | galactose binding | IEP | Predicted GO |
BP | GO:0006357 | regulation of transcription by RNA polymerase II | IEP | Predicted GO |
BP | GO:0009966 | regulation of signal transduction | IEP | Predicted GO |
BP | GO:0010629 | negative regulation of gene expression | IEP | Predicted GO |
BP | GO:0010646 | regulation of cell communication | IEP | Predicted GO |
BP | GO:0016458 | gene silencing | IEP | Predicted GO |
CC | GO:0016592 | mediator complex | IEP | Predicted GO |
MF | GO:0019899 | enzyme binding | IEP | Predicted GO |
BP | GO:0023051 | regulation of signaling | IEP | Predicted GO |
BP | GO:0031047 | gene silencing by RNA | IEP | Predicted GO |
BP | GO:0032012 | regulation of ARF protein signal transduction | IEP | Predicted GO |
BP | GO:0046578 | regulation of Ras protein signal transduction | IEP | Predicted GO |
MF | GO:0048029 | monosaccharide binding | IEP | Predicted GO |
BP | GO:0048583 | regulation of response to stimulus | IEP | Predicted GO |
MF | GO:0051020 | GTPase binding | IEP | Predicted GO |
BP | GO:0051056 | regulation of small GTPase mediated signal transduction | IEP | Predicted GO |
MF | GO:0140110 | transcription regulator activity | IEP | Predicted GO |
BP | GO:1902531 | regulation of intracellular signal transduction | IEP | Predicted GO |
No InterPro domains available for this sequence
No external refs found! |