PSME_00014296-RA


Description : (at1g15750 : 556.0) Encodes a protein with several WD40 repeats at the C-terminus and predicted protein-protein interaction domains at the N-terminus. Together with the TOPLESS-RELATED PROTEINS (TPRs), it is thought to be involved in transcriptional repression of root-promoting genes in the top help of the embryo during the transition stage of embryogenesis. The ability of IAA12 to repress transcription is diminished in a tpl-1 mutant background.; TOPLESS (TPL); FUNCTIONS IN: protein binding, transcription repressor activity, protein homodimerization activity; INVOLVED IN: xylem and phloem pattern formation, response to auxin stimulus, primary shoot apical meristem specification, jasmonic acid mediated signaling pathway; LOCATED IN: cytosol, nucleus; EXPRESSED IN: 27 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: WD40 repeat 2 (InterPro:IPR019782), WD40 repeat, conserved site (InterPro:IPR019775), WD40 repeat (InterPro:IPR001680), CTLH, C-terminal LisH motif (InterPro:IPR006595), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), LisH dimerisation motif (InterPro:IPR006594), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: TOPLESS-related 1 (TAIR:AT1G80490.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). & (reliability: 1112.0) & (original description: no original description)


Gene families : OG_42_0000373 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000373_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00014296-RA
Cluster HCCA clusters: Cluster_249

Target Alias Description ECC score Gene Family Method Actions
Bradi1g67800 No alias TOPLESS-related 1 0.04 Orthogroups_2024-Update
Bradi2g09080 No alias TOPLESS-related 2 0.03 Orthogroups_2024-Update
Glyma.08G214600 No alias Transducin family protein / WD-40 repeat family protein 0.02 Orthogroups_2024-Update
Glyma.10G150000 No alias TOPLESS-related 3 0.03 Orthogroups_2024-Update
Glyma.13G367300 No alias TOPLESS-related 1 0.03 Orthogroups_2024-Update
Glyma.15G006100 No alias TOPLESS-related 1 0.03 Orthogroups_2024-Update
Glyma.17G112500 No alias WUS-interacting protein 2 0.03 Orthogroups_2024-Update
HORVU6Hr1G036010.9 No alias Unknown function 0.04 Orthogroups_2024-Update
Kfl00881_0020 kfl00881_0020_v1.1 (at1g15750 : 1113.0) Encodes a protein with several WD40... 0.02 Orthogroups_2024-Update
MA_10430083g0010 No alias (at1g15750 : 1644.0) Encodes a protein with several WD40... 0.05 Orthogroups_2024-Update
MA_10436445g0020 No alias (at1g15750 : 1515.0) Encodes a protein with several WD40... 0.05 Orthogroups_2024-Update
MA_16979g0020 No alias (at1g15750 : 344.0) Encodes a protein with several WD40... 0.03 Orthogroups_2024-Update
Mp7g17410.1 No alias transcriptional repressor (TPL). transcriptional... 0.02 Orthogroups_2024-Update
Seita.9G466100.1 No alias auxin signalling transcriptional co-repressor *(TPL/TPR)... 0.02 Orthogroups_2024-Update
Sobic.007G051700.1 No alias auxin signalling transcriptional co-repressor *(TPL/TPR)... 0.02 Orthogroups_2024-Update

Type GO Term Name Evidence Source

No GO annotation available for this sequence

Type GO Term Name Evidence Source
MF GO:0003682 chromatin binding IEP Predicted GO
MF GO:0003712 transcription coregulator activity IEP Predicted GO
MF GO:0003714 transcription corepressor activity IEP Predicted GO
MF GO:0005085 guanyl-nucleotide exchange factor activity IEP Predicted GO
MF GO:0005086 ARF guanyl-nucleotide exchange factor activity IEP Predicted GO
MF GO:0005534 galactose binding IEP Predicted GO
BP GO:0006357 regulation of transcription by RNA polymerase II IEP Predicted GO
BP GO:0009966 regulation of signal transduction IEP Predicted GO
BP GO:0010629 negative regulation of gene expression IEP Predicted GO
BP GO:0010646 regulation of cell communication IEP Predicted GO
BP GO:0016458 gene silencing IEP Predicted GO
CC GO:0016592 mediator complex IEP Predicted GO
MF GO:0019899 enzyme binding IEP Predicted GO
BP GO:0023051 regulation of signaling IEP Predicted GO
BP GO:0031047 gene silencing by RNA IEP Predicted GO
BP GO:0032012 regulation of ARF protein signal transduction IEP Predicted GO
BP GO:0046578 regulation of Ras protein signal transduction IEP Predicted GO
MF GO:0048029 monosaccharide binding IEP Predicted GO
BP GO:0048583 regulation of response to stimulus IEP Predicted GO
MF GO:0051020 GTPase binding IEP Predicted GO
BP GO:0051056 regulation of small GTPase mediated signal transduction IEP Predicted GO
MF GO:0140110 transcription regulator activity IEP Predicted GO
BP GO:1902531 regulation of intracellular signal transduction IEP Predicted GO

No InterPro domains available for this sequence

No external refs found!