PSME_00023484-RA

Description : (at2g36910 : 1766.0) Belongs to the family of ATP-binding cassette (ABC) transporters. Also known as AtMDR1.Possibly regulates auxin-dependent responses by influencing basipetal auxin transport in the root. Exerts nonredundant, partially overlapping functions with the ABC transporter encoded by AT3G28860. PGP1 mediates cellular efflux of IAA and interacts with PIN genes that may confer an accelerated vectoral component to PGP-mediated transport. The non-polar localization of PGP1 at root and shoot apices, where IAA gradient-driven transport is impaired, may be required to confer directionality to auxin transport in those tissues.; ATP binding cassette subfamily B1 (ABCB1); FUNCTIONS IN: ATPase activity, coupled to transmembrane movement of substances, calmodulin binding, auxin efflux transmembrane transporter activity; INVOLVED IN: in 10 processes; LOCATED IN: plasma membrane; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ABC transporter-like (InterPro:IPR003439), ABC transporter, transmembrane domain, type 1 (InterPro:IPR011527), ABC transporter integral membrane type 1 (InterPro:IPR017940), ABC transporter, transmembrane domain (InterPro:IPR001140), ABC transporter, conserved site (InterPro:IPR017871); BEST Arabidopsis thaliana protein match is: ATP binding cassette subfamily B19 (TAIR:AT3G28860.1); Has 825599 Blast hits to 386427 proteins in 4134 species: Archae - 14573; Bacteria - 644325; Metazoa - 17752; Fungi - 12077; Plants - 9020; Viruses - 35; Other Eukaryotes - 127817 (source: NCBI BLink). & (q6yuu5|mdr_orysa : 1067.0) Putative multidrug resistance protein (P-glycoprotein) - Oryza sativa (Rice) & (reliability: 3532.0) & (original description: no original description)

Gene families : OG_42_0000040 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000040_tree

Sequence : coding (download), protein (download)

Attention: This gene has low abundance.

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pseudotsuga release: PSME_00023484-RA
Cluster	HCCA clusters: Cluster_10

Target	Alias	Description	ECC score	Gene Family Method
123915	No alias	P-glycoprotein 11	0.03	Orthogroups_2024-Update
139408	No alias	P-glycoprotein 20	0.02	Orthogroups_2024-Update
231714	No alias	P-glycoprotein 17	0.03	Orthogroups_2024-Update
92485	No alias	ATP binding cassette subfamily B19	0.02	Orthogroups_2024-Update
A4A49_00814	No alias	abc transporter b family member 4	0.04	Orthogroups_2024-Update
A4A49_01823	No alias	putative abc transporter b family member 8	0.02	Orthogroups_2024-Update
A4A49_25017	No alias	abc transporter b family member 9	0.03	Orthogroups_2024-Update
At1g28010	No alias	ABC transporter B family member 14...	0.03	Orthogroups_2024-Update
At3g28860	No alias	ABC transporter B family member 19...	0.02	Orthogroups_2024-Update
Bradi1g72517	No alias	ATP binding cassette subfamily B19	0.03	Orthogroups_2024-Update
Bradi2g47400	No alias	ATP binding cassette subfamily B4	0.02	Orthogroups_2024-Update
Brara.I01830.1	No alias	subfamily ABCB transporter	0.04	Orthogroups_2024-Update
Brara.I02993.1	No alias	subfamily ABCB transporter	0.04	Orthogroups_2024-Update
Brara.K00467.1	No alias	subfamily ABCB transporter	0.03	Orthogroups_2024-Update
GRMZM2G004748	No alias	P-glycoprotein 2	0.03	Orthogroups_2024-Update
GRMZM2G315375	No alias	ATP binding cassette subfamily B1	0.03	Orthogroups_2024-Update
Glyma.10G137600	No alias	ATP binding cassette subfamily B4	0.03	Orthogroups_2024-Update
Glyma.14G220200	No alias	P-glycoprotein 13	0.03	Orthogroups_2024-Update
Glyma.15G090200	No alias	P-glycoprotein 9	0.03	Orthogroups_2024-Update
Glyma.18G012700	No alias	P-glycoprotein 18	0.02	Orthogroups_2024-Update
Glyma.19G016600	No alias	ABC transporter family protein	0.03	Orthogroups_2024-Update
Glyma.19G016700	No alias	ABC transporter family protein	0.02	Orthogroups_2024-Update
HORVU7Hr1G063020.3	No alias	subfamily ABCB transporter	0.03	Orthogroups_2024-Update
Kfl00008_0360	kfl00008_0360_v1.1	(at1g02520 : 1200.0) P-glycoprotein 11 (PGP11);...	0.02	Orthogroups_2024-Update
Kfl00461_0020	kfl00461_0020_v1.1	(at3g28860 : 1090.0) Belongs to the family of...	0.02	Orthogroups_2024-Update
MA_111099g0010	No alias	(at3g28345 : 1122.0) ABC transporter family protein;...	0.04	Orthogroups_2024-Update
PSME_00046830-RA	No alias	(at3g28345 : 1028.0) ABC transporter family protein;...	0.04	Orthogroups_2024-Update
Potri.011G133800	No alias	P-glycoprotein 18	0.03	Orthogroups_2024-Update
Potri.017G085000	No alias	ABC transporter family protein	0.03	Orthogroups_2024-Update
Potri.018G141400	No alias	ABC transporter family protein	0.03	Orthogroups_2024-Update
Pp1s391_45V6	No alias	multidrug pheromone mdr abc transporter family	0.03	Orthogroups_2024-Update
Seita.1G055700.1	No alias	subfamily ABCB transporter	0.02	Orthogroups_2024-Update
Seita.1G280600.1	No alias	subfamily ABCB transporter	0.03	Orthogroups_2024-Update
Seita.5G302200.1	No alias	subfamily ABCB transporter	0.05	Orthogroups_2024-Update
Sobic.003G180400.1	No alias	subfamily ABCB transporter	0.04	Orthogroups_2024-Update
Sobic.004G073400.1	No alias	subfamily ABCB transporter	0.03	Orthogroups_2024-Update
Sobic.007G042600.1	No alias	subfamily ABCB transporter	0.02	Orthogroups_2024-Update
Sobic.007G163800.1	No alias	subfamily ABCB transporter	0.03	Orthogroups_2024-Update
Solyc03g005860	No alias	ABC transporter B family protein (AHRD V3.3 *** G7ILW7_MEDTR)	0.04	Orthogroups_2024-Update
Solyc06g072960	No alias	No description available	0.06	Orthogroups_2024-Update
Solyc08g076720	No alias	ABC transporter B family-like protein (AHRD V3.3 ***...	0.03	Orthogroups_2024-Update
Sopen02g032160	No alias	ABC transporter transmembrane region	0.05	Orthogroups_2024-Update
Sopen02g032590	No alias	ABC transporter transmembrane region	0.03	Orthogroups_2024-Update
Sopen06g004020	No alias	ABC transporter transmembrane region	0.02	Orthogroups_2024-Update
Sopen12g033620	No alias	ABC transporter transmembrane region	0.02	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0005215	transporter activity	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	InterProScan predictions
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0006810	transport	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
MF	GO:0015399	primary active transmembrane transporter activity	None	Extended
MF	GO:0015405	P-P-bond-hydrolysis-driven transmembrane transporter activity	None	Extended
CC	GO:0016021	integral component of membrane	IEA	InterProScan predictions
MF	GO:0016462	pyrophosphatase activity	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	None	Extended
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	None	Extended
MF	GO:0016887	ATPase activity	IEA	InterProScan predictions
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0017111	nucleoside-triphosphatase activity	None	Extended
MF	GO:0022804	active transmembrane transporter activity	None	Extended
MF	GO:0022857	transmembrane transporter activity	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
CC	GO:0031224	intrinsic component of membrane	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0042623	ATPase activity, coupled	None	Extended
MF	GO:0042626	ATPase activity, coupled to transmembrane movement of substances	IEA	InterProScan predictions
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
MF	GO:0043492	ATPase activity, coupled to movement of substances	None	Extended
CC	GO:0044425	membrane part	None	Extended
BP	GO:0051179	localization	None	Extended
BP	GO:0051234	establishment of localization	None	Extended
BP	GO:0055085	transmembrane transport	IEA	InterProScan predictions
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0003968	RNA-directed 5'-3' RNA polymerase activity	IEP	Predicted GO
MF	GO:0003993	acid phosphatase activity	IEP	Predicted GO
MF	GO:0004175	endopeptidase activity	IEP	Predicted GO
MF	GO:0004252	serine-type endopeptidase activity	IEP	Predicted GO
MF	GO:0004478	methionine adenosyltransferase activity	IEP	Predicted GO
MF	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity	IEP	Predicted GO
MF	GO:0005506	iron ion binding	IEP	Predicted GO
BP	GO:0006081	cellular aldehyde metabolic process	IEP	Predicted GO
BP	GO:0006098	pentose-phosphate shunt	IEP	Predicted GO
BP	GO:0006508	proteolysis	IEP	Predicted GO
BP	GO:0006556	S-adenosylmethionine biosynthetic process	IEP	Predicted GO
BP	GO:0006694	steroid biosynthetic process	IEP	Predicted GO
BP	GO:0006732	coenzyme metabolic process	IEP	Predicted GO
BP	GO:0006739	NADP metabolic process	IEP	Predicted GO
BP	GO:0008202	steroid metabolic process	IEP	Predicted GO
MF	GO:0008233	peptidase activity	IEP	Predicted GO
MF	GO:0016491	oxidoreductase activity	IEP	Predicted GO
MF	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	IEP	Predicted GO
MF	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	IEP	Predicted GO
MF	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	IEP	Predicted GO
BP	GO:0019682	glyceraldehyde-3-phosphate metabolic process	IEP	Predicted GO
MF	GO:0020037	heme binding	IEP	Predicted GO
MF	GO:0030246	carbohydrate binding	IEP	Predicted GO
MF	GO:0030976	thiamine pyrophosphate binding	IEP	Predicted GO
MF	GO:0043169	cation binding	IEP	Predicted GO
BP	GO:0046500	S-adenosylmethionine metabolic process	IEP	Predicted GO
MF	GO:0046872	metal ion binding	IEP	Predicted GO
MF	GO:0046906	tetrapyrrole binding	IEP	Predicted GO
MF	GO:0046914	transition metal ion binding	IEP	Predicted GO
MF	GO:0048037	cofactor binding	IEP	Predicted GO
MF	GO:0050662	coenzyme binding	IEP	Predicted GO
BP	GO:0051156	glucose 6-phosphate metabolic process	IEP	Predicted GO
BP	GO:0051186	cofactor metabolic process	IEP	Predicted GO
BP	GO:0055114	oxidation-reduction process	IEP	Predicted GO
MF	GO:0061630	ubiquitin protein ligase activity	IEP	Predicted GO
MF	GO:0061659	ubiquitin-like protein ligase activity	IEP	Predicted GO
MF	GO:0070011	peptidase activity, acting on L-amino acid peptides	IEP	Predicted GO
MF	GO:1901681	sulfur compound binding	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR011527	ABC1_TM_dom	787	1056
IPR011527	ABC1_TM_dom	111	384
IPR003439	ABC_transporter-like	1127	1275
IPR003439	ABC_transporter-like	475	623

External Links

No external refs found!

PSME_00023484-RA

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation