PSME_00034486-RA


Description : (at2g17265 : 366.0) Encodes a homoserine kinase (HSK) which produces O-phospho-L-homoserine (HserP), a compound at the branching point of methionine and threonine biosynthesis. HSK is found in the stromal fraction of chloroplasts. Mutants are susceptible to downy mildew fungus Hyaloperonospora parasitica.; homoserine kinase (HSK); FUNCTIONS IN: homoserine kinase activity; INVOLVED IN: methionine biosynthetic process, threonine biosynthetic process, response to fungus, response to bacterium; LOCATED IN: chloroplast stroma, chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: GHMP kinase, ATP-binding, conserved site (InterPro:IPR006203), Ribosomal protein S5 domain 2-type fold (InterPro:IPR020568), GHMP kinase (InterPro:IPR006204), Ribosomal protein S5 domain 2-type fold, subgroup (InterPro:IPR014721), Homoserine kinase (InterPro:IPR000870), GHMP kinase, C-terminal (InterPro:IPR013750); BEST Arabidopsis thaliana protein match is: homoserine kinase, putative / HSK, putative (TAIR:AT4G35295.1); Has 6092 Blast hits to 6088 proteins in 1935 species: Archae - 296; Bacteria - 4868; Metazoa - 7; Fungi - 124; Plants - 47; Viruses - 0; Other Eukaryotes - 750 (source: NCBI BLink). & (reliability: 732.0) & (original description: no original description)


Gene families : OG_42_0005266 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0005266_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00034486-RA
Cluster HCCA clusters: Cluster_17


Type GO Term Name Evidence Source
MF GO:0005524 ATP binding IEA InterProScan predictions
Type GO Term Name Evidence Source
MF GO:0003864 3-methyl-2-oxobutanoate hydroxymethyltransferase activity IEP Predicted GO
MF GO:0003872 6-phosphofructokinase activity IEP Predicted GO
MF GO:0004812 aminoacyl-tRNA ligase activity IEP Predicted GO
BP GO:0006082 organic acid metabolic process IEP Predicted GO
BP GO:0006090 pyruvate metabolic process IEP Predicted GO
BP GO:0006096 glycolytic process IEP Predicted GO
BP GO:0006165 nucleoside diphosphate phosphorylation IEP Predicted GO
BP GO:0006418 tRNA aminoacylation for protein translation IEP Predicted GO
BP GO:0006575 cellular modified amino acid metabolic process IEP Predicted GO
BP GO:0006732 coenzyme metabolic process IEP Predicted GO
BP GO:0006733 oxidoreduction coenzyme metabolic process IEP Predicted GO
BP GO:0006757 ATP generation from ADP IEP Predicted GO
BP GO:0006766 vitamin metabolic process IEP Predicted GO
BP GO:0006767 water-soluble vitamin metabolic process IEP Predicted GO
MF GO:0008443 phosphofructokinase activity IEP Predicted GO
BP GO:0009108 coenzyme biosynthetic process IEP Predicted GO
BP GO:0009110 vitamin biosynthetic process IEP Predicted GO
BP GO:0009132 nucleoside diphosphate metabolic process IEP Predicted GO
BP GO:0009135 purine nucleoside diphosphate metabolic process IEP Predicted GO
BP GO:0009166 nucleotide catabolic process IEP Predicted GO
BP GO:0009179 purine ribonucleoside diphosphate metabolic process IEP Predicted GO
BP GO:0009185 ribonucleoside diphosphate metabolic process IEP Predicted GO
BP GO:0015939 pantothenate metabolic process IEP Predicted GO
BP GO:0015940 pantothenate biosynthetic process IEP Predicted GO
BP GO:0016053 organic acid biosynthetic process IEP Predicted GO
MF GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor IEP Predicted GO
MF GO:0016741 transferase activity, transferring one-carbon groups IEP Predicted GO
MF GO:0016742 hydroxymethyl-, formyl- and related transferase activity IEP Predicted GO
MF GO:0016875 ligase activity, forming carbon-oxygen bonds IEP Predicted GO
MF GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors IEP Predicted GO
MF GO:0019200 carbohydrate kinase activity IEP Predicted GO
BP GO:0019359 nicotinamide nucleotide biosynthetic process IEP Predicted GO
BP GO:0019362 pyridine nucleotide metabolic process IEP Predicted GO
BP GO:0019363 pyridine nucleotide biosynthetic process IEP Predicted GO
BP GO:0019752 carboxylic acid metabolic process IEP Predicted GO
BP GO:0032787 monocarboxylic acid metabolic process IEP Predicted GO
BP GO:0034641 cellular nitrogen compound metabolic process IEP Predicted GO
BP GO:0042364 water-soluble vitamin biosynthetic process IEP Predicted GO
BP GO:0042398 cellular modified amino acid biosynthetic process IEP Predicted GO
BP GO:0042866 pyruvate biosynthetic process IEP Predicted GO
BP GO:0043038 amino acid activation IEP Predicted GO
BP GO:0043039 tRNA aminoacylation IEP Predicted GO
BP GO:0043436 oxoacid metabolic process IEP Predicted GO
BP GO:0044281 small molecule metabolic process IEP Predicted GO
BP GO:0044283 small molecule biosynthetic process IEP Predicted GO
BP GO:0046031 ADP metabolic process IEP Predicted GO
BP GO:0046394 carboxylic acid biosynthetic process IEP Predicted GO
BP GO:0046434 organophosphate catabolic process IEP Predicted GO
BP GO:0046496 nicotinamide nucleotide metabolic process IEP Predicted GO
BP GO:0046939 nucleotide phosphorylation IEP Predicted GO
BP GO:0051186 cofactor metabolic process IEP Predicted GO
BP GO:0051188 cofactor biosynthetic process IEP Predicted GO
BP GO:0072330 monocarboxylic acid biosynthetic process IEP Predicted GO
BP GO:0072524 pyridine-containing compound metabolic process IEP Predicted GO
BP GO:0072525 pyridine-containing compound biosynthetic process IEP Predicted GO
BP GO:1901292 nucleoside phosphate catabolic process IEP Predicted GO
InterPro domains Description Start Stop
IPR013750 GHMP_kinase_C_dom 281 359
IPR006204 GHMP_kinase_N_dom 153 218
No external refs found!