Description : (at3g11750 : 155.0) Encodes an enzyme that can act as a aldolase or an epimerase for 7,8-dihydroneopterin and 7,8-dihydromonapterin in vitro. It is likely to act in tetrahydrofolate biosynthesis in vivo.; FOLB1; FUNCTIONS IN: dihydroneopterin aldolase activity; INVOLVED IN: folic acid and derivative metabolic process; EXPRESSED IN: 19 plant structures; EXPRESSED DURING: 10 growth stages; CONTAINS InterPro DOMAIN/s: Dihydroneopterin aldolase (InterPro:IPR006157), Dihydroneopterin aldolase subgroup (InterPro:IPR006156); BEST Arabidopsis thaliana protein match is: Dihydroneopterin aldolase (TAIR:AT5G62980.1); Has 3723 Blast hits to 3723 proteins in 1537 species: Archae - 4; Bacteria - 2961; Metazoa - 0; Fungi - 2; Plants - 88; Viruses - 0; Other Eukaryotes - 668 (source: NCBI BLink). & (reliability: 310.0) & (original description: no original description)
Gene families : OG_42_0003430 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0003430_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Pseudotsuga release: PSME_00051949-RA | |
Cluster | HCCA clusters: Cluster_169 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
At5g62980 | No alias | Dihydroneopterin aldolase 2... | 0.02 | Orthogroups_2024-Update |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0004150 | dihydroneopterin aldolase activity | IEA | InterProScan predictions |
BP | GO:0006760 | folic acid-containing compound metabolic process | IEA | InterProScan predictions |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0001882 | nucleoside binding | IEP | Predicted GO |
MF | GO:0001883 | purine nucleoside binding | IEP | Predicted GO |
MF | GO:0003723 | RNA binding | IEP | Predicted GO |
MF | GO:0003729 | mRNA binding | IEP | Predicted GO |
MF | GO:0004665 | prephenate dehydrogenase (NADP+) activity | IEP | Predicted GO |
MF | GO:0004743 | pyruvate kinase activity | IEP | Predicted GO |
MF | GO:0004843 | thiol-dependent ubiquitin-specific protease activity | IEP | Predicted GO |
MF | GO:0005525 | GTP binding | IEP | Predicted GO |
CC | GO:0005622 | intracellular | IEP | Predicted GO |
CC | GO:0005849 | mRNA cleavage factor complex | IEP | Predicted GO |
BP | GO:0006357 | regulation of transcription by RNA polymerase II | IEP | Predicted GO |
BP | GO:0006378 | mRNA polyadenylation | IEP | Predicted GO |
BP | GO:0006570 | tyrosine metabolic process | IEP | Predicted GO |
BP | GO:0006571 | tyrosine biosynthetic process | IEP | Predicted GO |
MF | GO:0008234 | cysteine-type peptidase activity | IEP | Predicted GO |
MF | GO:0008977 | prephenate dehydrogenase (NAD+) activity | IEP | Predicted GO |
BP | GO:0009095 | aromatic amino acid family biosynthetic process, prephenate pathway | IEP | Predicted GO |
CC | GO:0016592 | mediator complex | IEP | Predicted GO |
MF | GO:0016628 | oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor | IEP | Predicted GO |
MF | GO:0019001 | guanyl nucleotide binding | IEP | Predicted GO |
MF | GO:0030955 | potassium ion binding | IEP | Predicted GO |
BP | GO:0031123 | RNA 3'-end processing | IEP | Predicted GO |
BP | GO:0031124 | mRNA 3'-end processing | IEP | Predicted GO |
MF | GO:0031420 | alkali metal ion binding | IEP | Predicted GO |
BP | GO:0032259 | methylation | IEP | Predicted GO |
MF | GO:0032549 | ribonucleoside binding | IEP | Predicted GO |
MF | GO:0032550 | purine ribonucleoside binding | IEP | Predicted GO |
MF | GO:0032561 | guanyl ribonucleotide binding | IEP | Predicted GO |
BP | GO:0043631 | RNA polyadenylation | IEP | Predicted GO |
CC | GO:0044428 | nuclear part | IEP | Predicted GO |
CC | GO:0044451 | nucleoplasm part | IEP | Predicted GO |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR006157 | FolB_dom | 13 | 123 |
No external refs found! |