HORVU4Hr1G012850.1

Description : catalytic component *(PS) of gamma secretase complex

Gene families : OG_42_0003309 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0003309_tree

Sequence : coding (download), protein (download)

Attention: This gene has low abundance.

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Hordeum vulgare: HORVU4Hr1G012850.1
Cluster	HCAA Clusters: Cluster_268

Target	Alias	Description	ECC score	Gene Family Method	Actions
LOC_Os01g16930	No alias	presenilin, putative, expressed	0.03	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004175	endopeptidase activity	None	Extended
MF	GO:0004190	aspartic-type endopeptidase activity	IEA	16Dec
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0006508	proteolysis	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0008233	peptidase activity	None	Extended
CC	GO:0016020	membrane	IEA	16Dec
BP	GO:0016485	protein processing	IEA	16Dec
MF	GO:0016787	hydrolase activity	None	Extended
BP	GO:0019538	protein metabolic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0051604	protein maturation	None	Extended
MF	GO:0070001	aspartic-type peptidase activity	None	Extended
MF	GO:0070011	peptidase activity, acting on L-amino acid peptides	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
MF	GO:0140096	catalytic activity, acting on a protein	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000062	fatty-acyl-CoA binding	IEP	Predicted GO
CC	GO:0000145	exocyst	IEP	Predicted GO
CC	GO:0000151	ubiquitin ligase complex	IEP	Predicted GO
CC	GO:0000152	nuclear ubiquitin ligase complex	IEP	Predicted GO
MF	GO:0004525	ribonuclease III activity	IEP	Predicted GO
MF	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	IEP	Predicted GO
CC	GO:0005680	anaphase-promoting complex	IEP	Predicted GO
CC	GO:0005839	proteasome core complex	IEP	Predicted GO
BP	GO:0006511	ubiquitin-dependent protein catabolic process	IEP	Predicted GO
BP	GO:0006887	exocytosis	IEP	Predicted GO
BP	GO:0009056	catabolic process	IEP	Predicted GO
BP	GO:0009057	macromolecule catabolic process	IEP	Predicted GO
BP	GO:0010498	proteasomal protein catabolic process	IEP	Predicted GO
MF	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	IEP	Predicted GO
MF	GO:0016891	endoribonuclease activity, producing 5'-phosphomonoesters	IEP	Predicted GO
MF	GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	IEP	Predicted GO
CC	GO:0019773	proteasome core complex, alpha-subunit complex	IEP	Predicted GO
BP	GO:0019941	modification-dependent protein catabolic process	IEP	Predicted GO
BP	GO:0030163	protein catabolic process	IEP	Predicted GO
BP	GO:0031145	anaphase-promoting complex-dependent catabolic process	IEP	Predicted GO
CC	GO:0031461	cullin-RING ubiquitin ligase complex	IEP	Predicted GO
MF	GO:0032296	double-stranded RNA-specific ribonuclease activity	IEP	Predicted GO
BP	GO:0032940	secretion by cell	IEP	Predicted GO
MF	GO:0033218	amide binding	IEP	Predicted GO
BP	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	IEP	Predicted GO
BP	GO:0043632	modification-dependent macromolecule catabolic process	IEP	Predicted GO
BP	GO:0044248	cellular catabolic process	IEP	Predicted GO
BP	GO:0044265	cellular macromolecule catabolic process	IEP	Predicted GO
CC	GO:0044448	cell cortex part	IEP	Predicted GO
BP	GO:0046903	secretion	IEP	Predicted GO
BP	GO:0051603	proteolysis involved in cellular protein catabolic process	IEP	Predicted GO
MF	GO:0061630	ubiquitin protein ligase activity	IEP	Predicted GO
MF	GO:0061659	ubiquitin-like protein ligase activity	IEP	Predicted GO
MF	GO:0097602	cullin family protein binding	IEP	Predicted GO
CC	GO:0099023	tethering complex	IEP	Predicted GO
BP	GO:1901565	organonitrogen compound catabolic process	IEP	Predicted GO
MF	GO:1901567	fatty acid derivative binding	IEP	Predicted GO
BP	GO:1901575	organic substance catabolic process	IEP	Predicted GO
MF	GO:1901681	sulfur compound binding	IEP	Predicted GO
MF	GO:1901981	phosphatidylinositol phosphate binding	IEP	Predicted GO
MF	GO:1902936	phosphatidylinositol bisphosphate binding	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR001108	Peptidase_A22A	40	467

External Links

No external refs found!

HORVU4Hr1G012850.1

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation