evm.model.tig00000042.125

Description : (at4g00450 : 87.8) Encodes the Arabidopsis homolog of the transcriptional regulator MED12, is dynamically expressed during embryogenesis and regulates both developmental timing and the radial pattern formation. Involved in flowering time. The mutant enhances the expression of the flowering time (FT) gene. A knockout mutant of this gene showed late-flowering phenotype.; CENTER CITY (CCT); FUNCTIONS IN: RNA polymerase II transcription mediator activity; INVOLVED IN: photoperiodism, flowering, regulation of development, heterochronic, regulation of radial pattern formation; LOCATED IN: mediator complex, chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Mediator complex, subunit Med12 (InterPro:IPR019035); Has 216 Blast hits to 184 proteins in 75 species: Archae - 0; Bacteria - 0; Metazoa - 42; Fungi - 65; Plants - 86; Viruses - 0; Other Eukaryotes - 23 (source: NCBI BLink). & (reliability: 175.6) & (original description: no original description)

Gene families : OG_42_0004166 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0004166_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Cyanophora release: evm.model.tig00000042.125
Cluster	HCCA clusters: Cluster_119

Target	Alias	Description	ECC score	Gene Family Method
Bradi1g21177	No alias	RNA polymerase II transcription mediators	0.01	Orthogroups_2024-Update
Cre12.g543850	No alias	Function unknown	0.01	Orthogroups_2024-Update
GRMZM2G114459	No alias	RNA polymerase II transcription mediators	0.03	Orthogroups_2024-Update
Glyma.07G070700	No alias	RNA polymerase II transcription mediators	0.01	Orthogroups_2024-Update
Kfl00777_0030	kfl00777_0030_v1.1	(at4g00450 : 130.0) Encodes the Arabidopsis homolog of...	0.01	Orthogroups_2024-Update
Seita.9G576200.1	No alias	component *(MED12) of kinase module of MEDIATOR...	0.01	Orthogroups_2024-Update
Sobic.001G540400.2	No alias	component *(MED12) of kinase module of MEDIATOR...	0.02	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003712	transcription coregulator activity	IEA	InterProScan predictions
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0006355	regulation of transcription, DNA-templated	None	Extended
BP	GO:0006357	regulation of transcription by RNA polymerase II	IEA	InterProScan predictions
BP	GO:0008150	biological_process	None	Extended
BP	GO:0009889	regulation of biosynthetic process	None	Extended
BP	GO:0010468	regulation of gene expression	None	Extended
BP	GO:0010556	regulation of macromolecule biosynthetic process	None	Extended
CC	GO:0016592	mediator complex	IEA	InterProScan predictions
BP	GO:0019219	regulation of nucleobase-containing compound metabolic process	None	Extended
BP	GO:0019222	regulation of metabolic process	None	Extended
BP	GO:0031323	regulation of cellular metabolic process	None	Extended
BP	GO:0031326	regulation of cellular biosynthetic process	None	Extended
CC	GO:0032991	protein-containing complex	None	Extended
CC	GO:0044422	organelle part	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044428	nuclear part	None	Extended
CC	GO:0044446	intracellular organelle part	None	Extended
CC	GO:0044451	nucleoplasm part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0050789	regulation of biological process	None	Extended
BP	GO:0050794	regulation of cellular process	None	Extended
BP	GO:0051171	regulation of nitrogen compound metabolic process	None	Extended
BP	GO:0051252	regulation of RNA metabolic process	None	Extended
BP	GO:0060255	regulation of macromolecule metabolic process	None	Extended
BP	GO:0065007	biological regulation	None	Extended
BP	GO:0080090	regulation of primary metabolic process	None	Extended
MF	GO:0140110	transcription regulator activity	None	Extended
BP	GO:1903506	regulation of nucleic acid-templated transcription	None	Extended
BP	GO:2000112	regulation of cellular macromolecule biosynthetic process	None	Extended
BP	GO:2001141	regulation of RNA biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000155	phosphorelay sensor kinase activity	IEP	Predicted GO
BP	GO:0000160	phosphorelay signal transduction system	IEP	Predicted GO
MF	GO:0004525	ribonuclease III activity	IEP	Predicted GO
MF	GO:0004559	alpha-mannosidase activity	IEP	Predicted GO
MF	GO:0004672	protein kinase activity	IEP	Predicted GO
MF	GO:0004673	protein histidine kinase activity	IEP	Predicted GO
MF	GO:0005315	inorganic phosphate transmembrane transporter activity	IEP	Predicted GO
MF	GO:0005543	phospholipid binding	IEP	Predicted GO
BP	GO:0006013	mannose metabolic process	IEP	Predicted GO
BP	GO:0006323	DNA packaging	IEP	Predicted GO
BP	GO:0006468	protein phosphorylation	IEP	Predicted GO
BP	GO:0006793	phosphorus metabolic process	IEP	Predicted GO
BP	GO:0006796	phosphate-containing compound metabolic process	IEP	Predicted GO
BP	GO:0006817	phosphate ion transport	IEP	Predicted GO
BP	GO:0007165	signal transduction	IEP	Predicted GO
BP	GO:0009165	nucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0009187	cyclic nucleotide metabolic process	IEP	Predicted GO
BP	GO:0009190	cyclic nucleotide biosynthetic process	IEP	Predicted GO
MF	GO:0015923	mannosidase activity	IEP	Predicted GO
MF	GO:0016301	kinase activity	IEP	Predicted GO
MF	GO:0016772	transferase activity, transferring phosphorus-containing groups	IEP	Predicted GO
MF	GO:0016773	phosphotransferase activity, alcohol group as acceptor	IEP	Predicted GO
MF	GO:0016775	phosphotransferase activity, nitrogenous group as acceptor	IEP	Predicted GO
MF	GO:0016829	lyase activity	IEP	Predicted GO
MF	GO:0016849	phosphorus-oxygen lyase activity	IEP	Predicted GO
BP	GO:0019318	hexose metabolic process	IEP	Predicted GO
BP	GO:0030261	chromosome condensation	IEP	Predicted GO
MF	GO:0032296	double-stranded RNA-specific ribonuclease activity	IEP	Predicted GO
BP	GO:0035556	intracellular signal transduction	IEP	Predicted GO
MF	GO:0140096	catalytic activity, acting on a protein	IEP	Predicted GO
BP	GO:1901293	nucleoside phosphate biosynthetic process	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR019035	Mediator_Med12	166	203

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evm.model.tig00000042.125

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation