1. Home
  2. GO
  3. GO:0000178

GO:0000178: exosome (RNase complex) (Cellular component)

"A ribonuclease complex that has 3-prime to 5-prime exoribonuclease activity and possibly endoribonuclease activity, producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured." [PMID:17174896, PMID:20531386, PMID:26726035]


There are 1456 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_143 Solanum pennellii 1.59 % 0.0028 0.034263
Cluster_8 Arabidopsis thaliana 0.79 % 0.009115 0.036334
Cluster_72 Arabidopsis thaliana 0.99 % 0.00731 0.034668
Cluster_99 Chlamydomonas reinhardtii 0.94 % 0.005975 0.028769
Cluster_59 Brachypodium distachyon 0.58 % 0.010059 0.039061
Cluster_342 Glycine max 1.3 % 0.007261 0.046389
Cluster_155 Cyanophora paradoxa 1.37 % 0.002955 0.036448
Cluster_10 Zea mays 0.68 % 0.009168 0.037397
Cluster_225 Zea mays 2.22 % 0.002833 0.012747
Cluster_259 Sorghum bicolor 2.0 % 0.001465 0.043951
Cluster_265 Setaria italica 2.22 % 0.001301 0.004684
Sequences (1456) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro Domains

Family Terms