evm.model.contig_3416.8

Description : (at1g08700 : 121.0) Encodes a protein similar to animal presenilin whose expression is increased in response to potassium (K+) deprivation.; Presenilin-1 (PS1); INVOLVED IN: intracellular signaling pathway; LOCATED IN: endomembrane system, integral to membrane, membrane; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Peptidase A22, presenilin signal peptide (InterPro:IPR006639), Peptidase A22A, presenilin (InterPro:IPR001108); BEST Arabidopsis thaliana protein match is: Presenilin-2 (TAIR:AT2G29900.1); Has 596 Blast hits to 445 proteins in 109 species: Archae - 4; Bacteria - 0; Metazoa - 417; Fungi - 0; Plants - 68; Viruses - 0; Other Eukaryotes - 107 (source: NCBI BLink). & (reliability: 242.0) & (original description: no original description)

Gene families : OG_42_0003309 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0003309_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Porphyridium release: evm.model.contig_3416.8
Cluster	HCCA clusters: Cluster_79

Target	Alias	Description	ECC score	Gene Family Method	Actions
Seita.5G041900.1	No alias	catalytic component *(PS) of gamma secretase complex	0.02	Orthogroups_2024-Update

1.0	Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004175	endopeptidase activity	None	Extended
MF	GO:0004190	aspartic-type endopeptidase activity	IEA	InterProScan predictions
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0006508	proteolysis	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0008233	peptidase activity	None	Extended
CC	GO:0016021	integral component of membrane	IEA	InterProScan predictions
BP	GO:0016485	protein processing	IEA	InterProScan predictions
MF	GO:0016787	hydrolase activity	None	Extended
BP	GO:0019538	protein metabolic process	None	Extended
CC	GO:0031224	intrinsic component of membrane	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
CC	GO:0044425	membrane part	None	Extended
BP	GO:0051604	protein maturation	None	Extended
MF	GO:0070001	aspartic-type peptidase activity	None	Extended
MF	GO:0070011	peptidase activity, acting on L-amino acid peptides	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
MF	GO:0140096	catalytic activity, acting on a protein	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000075	cell cycle checkpoint	IEP	Predicted GO
BP	GO:0000077	DNA damage checkpoint	IEP	Predicted GO
CC	GO:0000123	histone acetyltransferase complex	IEP	Predicted GO
CC	GO:0000124	SAGA complex	IEP	Predicted GO
CC	GO:0000813	ESCRT I complex	IEP	Predicted GO
MF	GO:0003712	transcription coregulator activity	IEP	Predicted GO
MF	GO:0003713	transcription coactivator activity	IEP	Predicted GO
MF	GO:0004518	nuclease activity	IEP	Predicted GO
MF	GO:0004519	endonuclease activity	IEP	Predicted GO
MF	GO:0004521	endoribonuclease activity	IEP	Predicted GO
MF	GO:0004525	ribonuclease III activity	IEP	Predicted GO
MF	GO:0004540	ribonuclease activity	IEP	Predicted GO
CC	GO:0005643	nuclear pore	IEP	Predicted GO
CC	GO:0005681	spliceosomal complex	IEP	Predicted GO
BP	GO:0006396	RNA processing	IEP	Predicted GO
BP	GO:0006405	RNA export from nucleus	IEP	Predicted GO
BP	GO:0006406	mRNA export from nucleus	IEP	Predicted GO
BP	GO:0006643	membrane lipid metabolic process	IEP	Predicted GO
BP	GO:0006664	glycolipid metabolic process	IEP	Predicted GO
BP	GO:0006913	nucleocytoplasmic transport	IEP	Predicted GO
BP	GO:0009247	glycolipid biosynthetic process	IEP	Predicted GO
BP	GO:0009891	positive regulation of biosynthetic process	IEP	Predicted GO
BP	GO:0009893	positive regulation of metabolic process	IEP	Predicted GO
BP	GO:0010557	positive regulation of macromolecule biosynthetic process	IEP	Predicted GO
BP	GO:0010604	positive regulation of macromolecule metabolic process	IEP	Predicted GO
BP	GO:0010628	positive regulation of gene expression	IEP	Predicted GO
BP	GO:0015931	nucleobase-containing compound transport	IEP	Predicted GO
BP	GO:0016197	endosomal transport	IEP	Predicted GO
MF	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	IEP	Predicted GO
MF	GO:0016891	endoribonuclease activity, producing 5'-phosphomonoesters	IEP	Predicted GO
MF	GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	IEP	Predicted GO
CC	GO:0030896	checkpoint clamp complex	IEP	Predicted GO
CC	GO:0031248	protein acetyltransferase complex	IEP	Predicted GO
BP	GO:0031325	positive regulation of cellular metabolic process	IEP	Predicted GO
BP	GO:0031328	positive regulation of cellular biosynthetic process	IEP	Predicted GO
BP	GO:0031570	DNA integrity checkpoint	IEP	Predicted GO
MF	GO:0032296	double-stranded RNA-specific ribonuclease activity	IEP	Predicted GO
BP	GO:0032509	endosome transport via multivesicular body sorting pathway	IEP	Predicted GO
CC	GO:0032991	protein-containing complex	IEP	Predicted GO
CC	GO:0036452	ESCRT complex	IEP	Predicted GO
CC	GO:0044422	organelle part	IEP	Predicted GO
CC	GO:0044428	nuclear part	IEP	Predicted GO
CC	GO:0044440	endosomal part	IEP	Predicted GO
CC	GO:0044446	intracellular organelle part	IEP	Predicted GO
CC	GO:0044451	nucleoplasm part	IEP	Predicted GO
CC	GO:0044454	nuclear chromosome part	IEP	Predicted GO
BP	GO:0045786	negative regulation of cell cycle	IEP	Predicted GO
BP	GO:0045893	positive regulation of transcription, DNA-templated	IEP	Predicted GO
BP	GO:0045935	positive regulation of nucleobase-containing compound metabolic process	IEP	Predicted GO
BP	GO:0046467	membrane lipid biosynthetic process	IEP	Predicted GO
BP	GO:0046907	intracellular transport	IEP	Predicted GO
BP	GO:0048518	positive regulation of biological process	IEP	Predicted GO
BP	GO:0048522	positive regulation of cellular process	IEP	Predicted GO
BP	GO:0050657	nucleic acid transport	IEP	Predicted GO
BP	GO:0050658	RNA transport	IEP	Predicted GO
BP	GO:0051028	mRNA transport	IEP	Predicted GO
BP	GO:0051168	nuclear export	IEP	Predicted GO
BP	GO:0051169	nuclear transport	IEP	Predicted GO
BP	GO:0051173	positive regulation of nitrogen compound metabolic process	IEP	Predicted GO
BP	GO:0051236	establishment of RNA localization	IEP	Predicted GO
BP	GO:0051254	positive regulation of RNA metabolic process	IEP	Predicted GO
BP	GO:0051259	protein complex oligomerization	IEP	Predicted GO
BP	GO:0051260	protein homooligomerization	IEP	Predicted GO
BP	GO:0051649	establishment of localization in cell	IEP	Predicted GO
MF	GO:0070403	NAD+ binding	IEP	Predicted GO
CC	GO:0070461	SAGA-type complex	IEP	Predicted GO
BP	GO:0071985	multivesicular body sorting pathway	IEP	Predicted GO
MF	GO:0140110	transcription regulator activity	IEP	Predicted GO
CC	GO:1902493	acetyltransferase complex	IEP	Predicted GO
BP	GO:1902680	positive regulation of RNA biosynthetic process	IEP	Predicted GO
BP	GO:1903508	positive regulation of nucleic acid-templated transcription	IEP	Predicted GO
BP	GO:1903509	liposaccharide metabolic process	IEP	Predicted GO
CC	GO:1905368	peptidase complex	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR001108	Peptidase_A22A	88	435

External Links

No external refs found!

evm.model.contig_3416.8

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation